KEGG   Oryctolagus cuniculus (rabbit): 100009528
Entry
100009528         CDS       T03373                                 
Symbol
CBR1
Name
(RefSeq) carbonyl reductase [NADPH] 1
  KO
K00079  carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00590  Arachidonic acid metabolism
ocu00790  Folate biosynthesis
ocu00980  Metabolism of xenobiotics by cytochrome P450
ocu01100  Metabolic pathways
ocu05204  Chemical carcinogenesis - DNA adducts
ocu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    100009528 (CBR1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100009528 (CBR1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100009528 (CBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100009528 (CBR1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100009528 (CBR1)
Enzymes [BR:ocu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.184  carbonyl reductase (NADPH)
     100009528 (CBR1)
    1.1.1.189  prostaglandin-E2 9-reductase
     100009528 (CBR1)
    1.1.1.197  15-hydroxyprostaglandin dehydrogenase (NADP+)
     100009528 (CBR1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase
Other DBs
NCBI-GeneID: 100009528
NCBI-ProteinID: NP_001076218
Ensembl: ENSOCUG00000027184
UniProt: P47844
LinkDB
AA seq 277 aa
MPSDRRVALVTGANKGVGFAITRALCRLFSGDVLLTAQDEAQGQAAVQQLQAEGLSPRFH
QLDITDLQSIRALRDFLRRAYGGLNVLVNNAVIAFKMEDTTPFHIQAEVTMKTNFDGTRD
VCTELLPLMRPGGRVVNVSSMTCLRALKSCSPELQQKFRSETITEEELVGLMKKFVEDTK
KGVHQTEGWPDTAYGVTKMGVTVLSRIQARHLSEHRGGDKILVNACCPGWVRTDMGGPNA
TKSPEEGAETPVYLALLPPDAEGPHGQFVMDKKVEQW
NT seq 834 nt   +upstreamnt  +downstreamnt
atgccgagtgaccgccgcgtggcgctggtgaccggcgccaacaagggcgtcggcttcgcc
atcacacgcgccctgtgccggctcttctcaggggacgtgcttctcacggcgcaggacgag
gcgcagggccaggccgccgtgcagcagctgcaggccgagggcctgagcccgcgcttccac
cagctggacatcacggacctgcagagcatccgcgccctgcgcgacttcctgcgccgggcg
tacgggggcctcaacgtgctggtcaacaacgcggtcatcgccttcaaaatggaggatacc
acgccctttcatattcaagcggaagtgactatgaagacaaactttgatggtacccgagat
gtctgcacagagctgctgcctctcatgaggcccggaggcagagtggtgaacgtgtccagc
atgacatgtctcagagcccttaaatcctgcagcccggagctgcagcagaagtttcgcagt
gagaccatcacggaggaggagctggtggggctcatgaagaagttcgtggaagacacgaag
aagggggtgcaccagacagaaggctggcctgacactgcctatggagtgaccaagatgggc
gtcactgtcttgtccagaatccaggccaggcacctgagtgagcacaggggaggggacaag
atcctcgtgaatgcttgctgcccagggtgggtgagaactgacatggggggacccaacgcc
accaagagcccagaagaaggagcagagacccccgtgtacttggcccttttgcctccagat
gccgagggccctcatgggcagtttgtcatggacaaaaaagttgaacagtggtga

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