KEGG   Oryctolagus cuniculus (rabbit): 100342863
Entry
100342863         CDS       T03373                                 
Name
(RefSeq) cytochrome P450 11B2, mitochondrial isoform X1
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00140  Steroid hormone biosynthesis
ocu01100  Metabolic pathways
ocu04927  Cortisol synthesis and secretion
ocu04934  Cushing syndrome
Module
ocu_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100342863
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    100342863
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100342863
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ocu00199]
    100342863
Enzymes [BR:ocu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     100342863
Cytochrome P450 [BR:ocu00199]
 Cytochrome P450, animal type
  CYP11 family
   100342863
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 100342863
NCBI-ProteinID: XP_051686984
LinkDB
Position
Unknown
AA seq 502 aa
MTFRARTAVWTAGPWLSLRDTRTLSTRAALSPKAALPFEAIPQCPSSQWMRMLQIWREKG
YENIHLEMHRTFQELGPIFRHDLGGRQFVSVMLPEDVERLQQVESRHPQRVHPEPWAAYR
QHRGQKCGVFLLNGPEWRSNRLKLNPVILSPKAVEKFIPMVDVVAREFLQVLQEKVQQNA
RGSLTMDVRPRILSYTIEASNFALFGERLGLLGQKITPVSLNFMHALEAMFRSTVELMFL
PRSLSRWTSAKAWKEHFEAWDHISQYAEQRIENISQELAGDCSGHYGGIVAELLRHADLS
PEAIKANSLELTAGSVDTTSLPLLMTLFELARNPDLQQALRQETRAAAASISAHPQRVIS
DLPLLRAALKETLRLYPVGLNLERIVSSDLVLQNHHIPAGTHVQVFLYALGRNPAVFPRP
ERYFPQRWLDRGPHQSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHVLKCFLLETLSPEDV
NMVYCFVMKPTNYPLLTFRPVN
NT seq 1509 nt   +upstreamnt  +downstreamnt
atgacattcagggcaaggacagctgtgtggacggcagggccttggctgtctctgcgagac
accaggacgctgagcaccagggcggctctgtctcccaaggctgcgctgccctttgaagcc
atcccccagtgtcccagctcccagtggatgaggatgctgcagatctggagagagaagggg
tatgagaacatccacctggagatgcatcgcaccttccaggagctggggcccattttcagg
catgacctggggggacgacaattcgtgtctgtgatgctgccggaggacgtggagaggctg
cagcaggtggagagccggcacccccagcgtgtgcacccagagccctgggcggcctacaga
cagcatcgtggacagaaatgtggcgtgttcttgctgaatggacctgaatggcgaagcaat
cgtttgaagctgaacccagtcatactgtcaccaaaggccgtggagaagttcatccccatg
gtggacgtggtggccagggaattcttacaggtcctgcaggagaaggtgcagcagaacgca
cgtgggagcctcaccatggacgtccggcccagaatcttgagctacaccatagaagccagc
aactttgcactttttggggagcgtctgggcctccttggccagaaaataacccctgtcagc
ctgaacttcatgcatgccctggaggccatgttcagatccactgtggagctcatgttcctg
cccagaagcctgtctcgctggaccagcgccaaggcgtggaaggagcactttgaggcctgg
gaccacatttcccagtatgccgaacagcgcattgagaacatctcccaggagctggcagga
gactgctctgggcactacggtggcatcgtggccgagctgctgaggcatgcggacttgtca
cctgaggccatcaaggccaactctcttgaactcacagcaggcagcgtggacacgacttct
ctccccttgctgatgacgctctttgagctggctcgcaaccccgacttgcagcaggccctg
cgccaggagactcgggcagctgcagccagcatctctgcccatccccagagggtcatctca
gacctgcccctgctgcgggctgccctcaaggagaccttgaggctctatcctgtgggtttg
aatttggagcggatagtcagctcagacctggtgctgcagaaccaccacatcccagctggg
acacacgtccaggtgttcctctacgcgctgggtcgcaatccggccgtattcccgaggcct
gagcgctatttcccccagcgctggcttgacaggggcccacatcagagcttccagcacctg
gcgtttggctttggggtgcgccagtgcctggggcgtcgcctggcagaagtggagatgctg
ctcctgctgcaccacgtgctgaaatgcttcctgctggagacgctatccccggaggatgtg
aacatggtgtactgctttgtcatgaagcccaccaactaccccctcctcacctttcggcct
gtcaactag

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