Otolemur garnettii (small-eared galago): 100955472 Help Entry 100955472         CDS       T07855                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism oga  Otolemur garnettii (small-eared galago) Pathway oga00230   Purine metabolism oga01100   Metabolic pathways oga01522   Endocrine resistance oga04015   Rap1 signaling pathway oga04020   Calcium signaling pathway oga04022   cGMP-PKG signaling pathway oga04024   cAMP signaling pathway oga04062   Chemokine signaling pathway oga04072   Phospholipase D signaling pathway oga04114   Oocyte meiosis oga04211   Longevity regulating pathway oga04213   Longevity regulating pathway - multiple species oga04261   Adrenergic signaling in cardiomyocytes oga04270   Vascular smooth muscle contraction oga04371   Apelin signaling pathway oga04540   Gap junction oga04611   Platelet activation oga04713   Circadian entrainment oga04714   Thermogenesis oga04720   Long-term potentiation oga04723   Retrograde endocannabinoid signaling oga04724   Glutamatergic synapse oga04725   Cholinergic synapse oga04727   GABAergic synapse oga04750   Inflammatory mediator regulation of TRP channels oga04911   Insulin secretion oga04912   GnRH signaling pathway oga04913   Ovarian steroidogenesis oga04914   Progesterone-mediated oocyte maturation oga04915   Estrogen signaling pathway oga04916   Melanogenesis oga04918   Thyroid hormone synthesis oga04921   Oxytocin signaling pathway oga04923   Regulation of lipolysis in adipocytes oga04925   Aldosterone synthesis and secretion oga04926   Relaxin signaling pathway oga04927   Cortisol synthesis and secretion oga04928   Parathyroid hormone synthesis, secretion and action oga04934   Cushing syndrome oga04935   Growth hormone synthesis, secretion and action oga04970   Salivary secretion oga04971   Gastric acid secretion oga04972   Pancreatic secretion oga04976   Bile secretion oga05032   Morphine addiction oga05142   Chagas disease oga05146   Amoebiasis oga05163   Human cytomegalovirus infection oga05166   Human T-cell leukemia virus 1 infection oga05200   Pathways in cancer oga05207   Chemical carcinogenesis - receptor activation oga05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oga00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100955472 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100955472 (ADCY1)    04371 Apelin signaling pathway     100955472 (ADCY1)    04020 Calcium signaling pathway     100955472 (ADCY1)    04072 Phospholipase D signaling pathway     100955472 (ADCY1)    04024 cAMP signaling pathway     100955472 (ADCY1)    04022 cGMP-PKG signaling pathway     100955472 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100955472 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     100955472 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100955472 (ADCY1)    04062 Chemokine signaling pathway     100955472 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     100955472 (ADCY1)    04923 Regulation of lipolysis in adipocytes     100955472 (ADCY1)    04912 GnRH signaling pathway     100955472 (ADCY1)    04913 Ovarian steroidogenesis     100955472 (ADCY1)    04915 Estrogen signaling pathway     100955472 (ADCY1)    04914 Progesterone-mediated oocyte maturation     100955472 (ADCY1)    04921 Oxytocin signaling pathway     100955472 (ADCY1)    04926 Relaxin signaling pathway     100955472 (ADCY1)    04935 Growth hormone synthesis, secretion and action     100955472 (ADCY1)    04918 Thyroid hormone synthesis     100955472 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     100955472 (ADCY1)    04916 Melanogenesis     100955472 (ADCY1)    04925 Aldosterone synthesis and secretion     100955472 (ADCY1)    04927 Cortisol synthesis and secretion     100955472 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100955472 (ADCY1)    04270 Vascular smooth muscle contraction     100955472 (ADCY1)   09154 Digestive system    04970 Salivary secretion     100955472 (ADCY1)    04971 Gastric acid secretion     100955472 (ADCY1)    04972 Pancreatic secretion     100955472 (ADCY1)    04976 Bile secretion     100955472 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     100955472 (ADCY1)    04727 GABAergic synapse     100955472 (ADCY1)    04725 Cholinergic synapse     100955472 (ADCY1)    04720 Long-term potentiation     100955472 (ADCY1)    04723 Retrograde endocannabinoid signaling     100955472 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100955472 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     100955472 (ADCY1)    04213 Longevity regulating pathway - multiple species     100955472 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     100955472 (ADCY1)    04714 Thermogenesis     100955472 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100955472 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     100955472 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100955472 (ADCY1)    05163 Human cytomegalovirus infection     100955472 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     100955472 (ADCY1)    05142 Chagas disease     100955472 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     100955472 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100955472 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100955472 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100955472 (ADCY1) Enzymes [BR:oga01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100955472 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 HNOBA Motif Other DBs NCBI-GeneID:  100955472 NCBI-ProteinID:  XP_012665511 Ensembl:  ENSOGAG00000004687 LinkDB All DBs Position Unknown AA seq 893 aa AA seqDB search MYGVFVRILTERSQRKAFLQARSYIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSF LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADL NFFTLKYKHAEREQKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNS TLVVFSSGGRRTALPALPCESAYHALLCCLVGTLPLAIFLRVSSLPKMILLCGLTMSYIL VLELSGYTRAGGSTISGRSYEPIMAILLFSCALALHARQVDVRLRLDYLWAAQAEEERED MERVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELD GNNMGVECLRLLNEIIADFDKLMDKDFYKDLEKIKTIGSTYMAAVGLAPTSGTKAKKSIS AHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNV ASRMDSTGVQGRIQVTEEVHRLLRRCSYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGAQT RPLGLERKMCPYGRASLQARHPTVCPSGLPVRAGLPPHPPSQCVPSTASGREA NT seq 2682 nt NT seq  +upstreamnt  +downstreamnt atgtacggggtctttgtgaggatcctgacggagcgctcccagaggaaggcattcctgcag gcccggagctacattgaggatcggctgaggctggaggatgagaacgagaagcaggagcga ctcctcatgagcctcctgccacggaatgttgccatggagatgaaggaagactttctgaag ccccctgagaggattttccacaagatttacatccagaggcatgacaatgtgagcatcctg tttgcagacatcgtgggcttcacaggcctggcctcccagtgcactgcccaggagctggtg aaactcctcaatgagctctttggcaagttcgacgaattagccacagagaaccactgtcgc cgcatcaagatcctcggggactgttactactgtgtgtcaggcctcacccaacccaagacc gaccacgcccactgctgtgtggagatggggctggacatgatcgacaccatcacgtctgta gctgaggccactgaagtggatttgaacatgcgtgtgggtctgcacacgggcagggtcctc tgtggcgtcctgggcctgcgcaaatggcaatatgatgtgtggtccaacgatgtgaccttg gccaatgtgatggaagctgcgggcctaccggggaaggttcacatcacaaagacgaccctg gcgtgcttgaatggggactatgaggtagaaccaggctatgggcatgagaggaacagtttc ctgaaaactcataatatcgagaccttttttattgtgccatcccatcgcagaaagatattt ccaggcctgattctgtcagatataaaaccggcaaaaaggatgaagttcaagacagtgtgc tacctgctggtgcagctcatgcactgccggaagatgttcaaggctgagatccccttctcc aacgtcatgacctgcgaggacgatgacaagcggagggcattgagaacagcctcagaaaag ctcagaaaccgttcatccttctctaccaacgtcgtctacaccaccccaggcactcgtgtc aacaggtacatcagccgcctcttagaagcacgccagacagagctggagatggcggacctg aacttctttaccctgaagtacaaacatgctgagcgggagcaaaagtaccaccagcttcag gacgagtatttcaccagcgctgttgtccttgccctcatcctggctgccttatttggcctt gtctaccttctaataatcccacagagtgtggccgtcctgctcctgctagtgttctgcatt tgtttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccaggg tgcctgacgattcagattcgcaccgtcttgtgtattttcatagtggtcttaatctattca gtagcccaaggatgtgtggtgggctgcctgccctgggcctggagctccaagcccaacagt accctggtggtcttctcatccgggggccggcgcacagcactgcccgccctgccctgcgag tctgcataccacgcccttctctgctgcctggtgggcaccctcccgctagccatattcctg cgggtgtcctccttgccaaaaatgatcctgctgtgtgggctcaccatgtcctacatcctc gtcctagagctcagtggatacaccagagccgggggcagcaccatctctgggcgcagctac gagccgatcatggccatcctgctgttctcctgtgcgctggccctgcacgccaggcaggtg gacgtcaggctgcggctggactacctctgggctgcacaggcagaagaggagcgcgaggac atggagagggtgaagctggacaacaggagaatcctcttcaacctcctgcctgcccatgtc gcccagcacttcctcatgtccaacccccggaacatggacctctactaccagtcctactct caggtgggtgtcatgttcgcctccatccccaacttcaacgacttctacatcgagctggac ggcaacaacatgggggtggagtgcctgcggctgctcaacgagatcatcgccgacttcgac aagctcatggacaaagacttttacaaggacctagagaagattaaaaccattgggagcacc tacatggccgcggtggggctggcgcccacctcggggaccaaggctaagaagtccatctct gcccacctgagcacgctggcagactttgccattgagatgtttgacgtcctggatgaaatc aactaccagtcttacaacgacttcgtcctccgagttggcatcaacgtcggccctgtggtg gccggagtgattggggcccgcaggccccagtacgacatctggggaaacacagtcaacgtg gcaagtcgaatggacagcactggagtccagggcagaatccaggtgactgaagaagtgcac cgactactgagaaggtgttcctaccacttcgtgtgccgaggcaaagtcagtgtcaagggc aagggtgagatgttgacatactttttggaaggcaggactgatggaaatggtgcccagact aggcccctaggcttggagcggaaaatgtgtccttatgggagagccagccttcaggccaga caccccactgtgtgccccagtgggctccctgtcagggctgggctccccccacacccccct agccagtgtgtgccctccacggcatctgggagggaggcttaa

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