Otolemur garnettii (small-eared galago): 100964949 Help Entry 100964949         CDS       T07855                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism oga  Otolemur garnettii (small-eared galago) Pathway oga04064   NF-kappa B signaling pathway oga04380   Osteoclast differentiation oga04650   Natural killer cell mediated cytotoxicity oga04658   Th1 and Th2 cell differentiation oga04659   Th17 cell differentiation oga04660   T cell receptor signaling pathway oga05135   Yersinia infection oga05166   Human T-cell leukemia virus 1 infection oga05235   PD-L1 expression and PD-1 checkpoint pathway in cancer oga05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:oga00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100964949 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100964949 (LCK)    04660 T cell receptor signaling pathway     100964949 (LCK)    04658 Th1 and Th2 cell differentiation     100964949 (LCK)    04659 Th17 cell differentiation     100964949 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     100964949 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100964949 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100964949 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     100964949 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     100964949 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oga01001]     100964949 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oga03036]     100964949 (LCK) Enzymes [BR:oga01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100964949 (LCK) Protein kinases [BR:oga01001]  Non-receptor tyrosine kinases   SRC family    100964949 (LCK) Chromosome and associated proteins [BR:oga03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     100964949 (LCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH3_16 SH3_3 Haspin_kinase Motif Other DBs NCBI-GeneID:  100964949 NCBI-ProteinID:  XP_012667841 Ensembl:  ENSOGAG00000005705 UniProt:  H0WSN1 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCGCSSNPEDDWMESIDVCENCHYPIVPLDGKATLPMRNGSDVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFQKGEQLRILEQSGEWWKAQSLTTGLEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDKGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGFYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTISKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSGTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYDLMMLCWKEH PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtggctgcagctcaaaccctgaagacgactggatggaaagcatcgatgtttgt gagaactgccattatcccatagtcccactggatggcaaggccacgctgcccatgcgaaat ggctctgacgtgcgggacccactggtcacctatgagggctccaatccaccagcctcccca ctgcaagacaacctggttattgctctgcacagctatgagccctctcatgatggagacctg ggcttccaaaagggtgaacagctccggatcctggagcagagcggcgagtggtggaaggcg cagtccctgaccaccggcctggaaggcttcatccccttcaactttgtggccaaagccaac agcctggagcctgaaccctggttctttaaaaacctgagccgcaaggatgcagagcgacag ctcctagcgcctgggaacacacatggctctttcctgatccgggagagcgagagcactgcg ggatcgttttcactatcggtccgggacttcgaccagaaccagggagaggtggtaaaacat tacaagatccgtaacctggataaaggcggcttctacatctcccctcgcatcacctttccc ggcctgcatgaactggtccgccattacaccaatgcttcagatgggctgtgcacccggttg agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt cccagagagacgctgaaattggttgagcggctgggggctggccagttcggggaagtgtgg atggggttctacaatgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg tcccctgatgccttcctggctgaggccaacctcatgaagcagctgcaacaccagcggctg gtccggctctatgcagtggtcacccaggagcccatctatatcatcactgaatacatggag aatgggagtctggtggattttctcaagaccccaccaggtatcaagttgaccatcagtaaa ctcctggacatggcagcccaaatcgcagagggcatggcattcattgaagagcggaattat atccaccgtgaccttcgggctgccaacattctggtgtctggcaccctgagctgcaagatt gcagactttggcttagcacgcctcattgaagacaacgaatatacagccagggagggagcc aagtttcccattaagtggacagcaccagaagccattaactatgggacattcaccatcaag tcggatgtgtggtctttcgggattctgctgacagagattgtcactcatgggcgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgtatggtg cgacctgataactgtcccgaggaactgtacgacctcatgatgctgtgctggaaggagcac ccagaggaccggcccacctttgactacttgcgcagtgtactggaggacttcttcacagcc acagagggccaataccagcctcagccttga

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