Oncorhynchus keta (chum salmon): 118402761
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Entry
118402761 CDS
T09424
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
oke
Oncorhynchus keta (chum salmon)
Pathway
oke00270
Cysteine and methionine metabolism
oke00480
Glutathione metabolism
oke01100
Metabolic pathways
oke01240
Biosynthesis of cofactors
oke04216
Ferroptosis
Module
oke_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
oke00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
118402761 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
118402761 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
118402761 (gclc)
Enzymes [BR:
oke01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
118402761 (gclc)
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Gene cluster
GFIT
Motif
Pfam:
GCS
GCS2
DUF2811
HasA
Motif
Other DBs
NCBI-GeneID:
118402761
NCBI-ProteinID:
XP_035656874
EnsemblRapid:
ENSOKEG00005008829
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All DBs
Position
24:complement(16204084..16212125)
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AA seq
630 aa
AA seq
DB search
MGLLSKGSPLNWEETKKYADHVRKHGIVQFLNIYNKVKERQKDVLLWGDEVEYMLIEMDE
KNGKVRLVLNGGEVLETLQDKGENTNPNHPTLWRPEYGGYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSVLNKNETLATITSFPRLGCPGFTQPEYKPTPVEKGVSKSLFFPDEAI
SQHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEKFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIEEARYLYDQLATFCPIMMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTGEERGLEPLKTNKFRILKSRYDSIDSYLSSCGDRYNDIDLTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSIFEEKIYMDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAFVVFIVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDIYKGCNPALDSSSSAAQNGLDSEGDNEYTLMSIDTIINGKEGIFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKRRASGELMTMAKWMREFVDKHPQYKQDSVITDRI
NYDLLRKCDSITKGEERCPELIGDPVNRGK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcaaaagggtcaccgctcaactgggaagaaaccaaaaagtatgcagac
catgttcggaaacatggcatcgttcagtttctcaacatctataacaaggtgaaagaacga
cagaaagatgtcttattatggggcgatgaggtggaatacatgttgatcgaaatggatgag
aaaaatggaaaggtacgtcttgttctcaatggtggggaggttttggaaacccttcaagac
aaaggagaaaacaccaaccccaaccatcctaccctttggaggccagagtatggcggctac
atgatcgaagggactccggggcagccctatggtgggacgatgtcagagttcaacacagtg
gaggacaacatggggaagcgaaggcgagaggcctcatctgtgctgaataagaatgaaacg
cttgccaccatcacgtcattcccaaggttaggctgcccaggcttcacacagccagaatac
aagccaacacctgttgaaaagggagtgtcaaaatcactgttcttcccagatgaagccata
agccaacacccaagattcagcaccctgaccagaaacattcgtcacagaagaggagagaag
gtggtgatcaacgtacccatctttaaagacaaatgcaccccatctccatttgtggagaag
tttccggaagacgatggggaggctgccagggcagctctacctgatcacatctacatggat
gccatgggatttggaatgggcaactgctgtcttcaggtgacattccaagcttgcagcatt
gaagaggcgaggtacctttatgaccaactagcaacattctgccctataatgatggccctc
agtgctgcttcgccattctacagaggctatgtgtcagacattgattgtcgctggggagtt
atttctgcctcggtagatgacaggaccggggaagagagggggctggagcctttgaaaacc
aacaaatttcgaatcttgaaatccagatatgattcaatcgacagctacctctccagctgt
ggcgataggtacaatgacatagatctgacaatagacgaggagatcaacaaacagctgctg
gatgcagggatcgacaaactgctggcccaacacatagcccatctcttcattcgggatccg
ctctcaatatttgaagagaaaatttacatggatgatgaaaacgagtctgatcactttgag
aatctgcagtcaaccaattggcagacaatgaggttcaaacctcctcctccaaactcggac
atcggatggcgagttgagttccgtcccatggaggtgcaacttaccgattttgaaaactct
gcattcgttgttttcatcgtcctgctcaccagggttatactgtcctataaactggacttt
ctcatccccttgtcaaaggttgacgaaaacatgaaagttgcccagaaaagaaatgcagtc
caagagggcatgttttacttccgtaaggacatctataaaggctgcaaccctgccctcgat
agctcctcatcggctgcccagaatggcttggacagtgagggtgacaatgagtacacactg
atgagcattgacacaatcatcaatggaaaggaaggaatttttcaagggttgataccaatc
ctcaactgctacctagaaaacatggaggtggatgttgatacaagatgcaccatcctgaac
tacctgaagctcatcaagagacgtgcctccggtgaactgatgaccatggctaaatggatg
agggagtttgtggacaagcacccccaatacaagcaagacagtgtcataactgacagaatc
aactacgacctactccgcaagtgtgacagcatcacaaaaggagaggagcgatgcccagaa
cttattggtgacccagtcaatcggggcaaatga
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