Onychostoma macrolepis: 131526069
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Entry
131526069 CDS
T09350
Symbol
hsd17b8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
omc
Onychostoma macrolepis
Pathway
omc00061
Fatty acid biosynthesis
omc00140
Steroid hormone biosynthesis
omc01100
Metabolic pathways
omc01212
Fatty acid metabolism
Module
omc_M00873
Fatty acid biosynthesis in mitochondria, animals
omc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
omc00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
131526069 (hsd17b8)
00140 Steroid hormone biosynthesis
131526069 (hsd17b8)
Enzymes [BR:
omc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
131526069 (hsd17b8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
131526069 (hsd17b8)
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GFIT
Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
Polysacc_synt_2
3Beta_HSD
RmlD_sub_bind
3HCDH_N
GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID:
131526069
NCBI-ProteinID:
XP_058610145
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Position
19:complement(28597613..28600536)
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AA seq
256 aa
AA seq
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MAASSRLISRLTLVTGGGSGIGRAVCQRFASEGASVIVADLNEESANQTLELLSHDLRGQ
QHMALGVDVSSKDSVEKLVTSVQRRYFQPPSVCVNAAGITQDDFLLKMEEDDFDKVIKIN
LKGTFLVTQAVSKALVSAGAVKGSIITVGSIVGKVGNIGQVNYSASKAGVEGLTRTAAKE
LSKFGIRCNCVLPGFITTPMTDKVPEKVIDKLTAIIPVGRMGEPAEVADACAFLASDDSR
YITGISIEVAGGLFIG
NT seq
771 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgtcctcgcgactcatatccaggctgacattagtgacaggaggcggcagtggc
attggcagggctgtgtgtcagaggttcgcctctgaaggagcttctgtaatagtggctgac
ctcaatgaagaatcagccaatcagacgctggagctgctgtcacatgacctcagaggtcag
cagcacatggccctgggggtggatgtgtcatctaaggacagtgtggagaaactagtgaca
agtgtacagcgccgctacttccagcctccgtctgtgtgtgtgaatgcagccgggatcacg
caagatgacttccttctcaagatggaagaagatgattttgacaaagtaatcaagattaat
ctcaagggcacgtttctcgtgactcaggccgtctcgaaggctttagtttctgcaggagct
gtgaagggctccatcatcactgtgggcagcatcgtgggcaaggttgggaatatcgggcag
gtgaactactccgcttctaaagccggagtggagggactcactcgaaccgctgccaaagag
ctgagcaaatttggcattcgctgcaactgtgtcctgcccgggttcatcactacacccatg
acagataaagtaccagagaaagtcatcgataaactcacagccatcattccagtgggaaga
atgggagaacctgctgaagtagctgatgcatgtgcatttctggcttctgatgacagtcga
tatattactggaatcagcattgaagttgctggtggactcttcattggctga
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