Oncorhynchus mykiss (rainbow trout): 110508583 Help Entry 110508583         CDS       T07259                                  Symbol obscnb Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism omy  Oncorhynchus mykiss (rainbow trout) Pathway omy04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:omy00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     110508583 (obscnb)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:omy01001]     110508583 (obscnb)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:omy04131]     110508583 (obscnb) Enzymes [BR:omy01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      110508583 (obscnb) Protein kinases [BR:omy01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    110508583 (obscnb) Membrane trafficking [BR:omy04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     110508583 (obscnb) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_5 Ig_4 Izumo-Ig Ig_6 V-set_CD47 C1-set fn3 BiPBP_C RhoGEF C2-set_2 PH SH3_2 PapD_C Motif Other DBs NCBI-GeneID:  110508583 NCBI-ProteinID:  XP_036822859 LinkDB All DBs Position 28:complement(13104078..13208077) Genome browser AA seq 6712 aa AA seqDB search MDQNLFGGAPRFLTRPKAFAVCVGKDATLSCTIVGNPTLLITWEKEKLRLTSGGRFKTVD DGNVYRLTIYDLTLEDSGQYMCRAKNNVGEAYACVTLHVGLPQEMVDRAPVFMVKPTSAR VGLGGDVVFHCRVAAYPEPKFDWDKDGRYLAETNRIKVSSDGDSSSLRIQSVRSLDSGTY TCRAQNSVGRSNSAAALVIDTQDSRHLGQDKSTSLLSHMQKRKEGISIYRTAETRSSSHN STTTSSTATTMVTDGLSALGLDHGSAALVSQLPKSVFTRTCTVTEGKHAKLSCFVTGHPK PHIIWRKDGGNIGEGRRHIMYEDQAENFILKILYCKQSDNGLYTCNASNMAGQTYSAVLV IVKEPKVPFRRKLQDVEVQEKMTAMLLCEVPVSASQASWFMEETRLEDSSKYCMEEEGTM RRLTIRNVTTNDDAVYICEMKEGSRTVAELTVLGNITKKLPRRTVVSVSDTVIFCVELEH PCSDAYWTRNGERLKPDTRISIACTLRQYTLTISHCQADDSGEVAFVAGDCKTSTRFSVT AARKHPPDPPIDVVVRNKTDSSITLHWSPPDSDRPVPIKGYMVERRKVGAQTWQRCNGME VSPFTEITIQNITEEASYQFRISAVNDYGQSQYVEVPGTFYLEPSAEVKTGLMNSTAISG EEASLSVDLSAVCSGSWSINGRLLRSGADYLITRQKTTHTLTIRTVSMEMNGAAVKFVGG GSESSCILHVKAPAVRFTSKSAHTEVVTCSAQSSAQLTTEVSDYDAQVVWMKNGRELKVG KKYECISTDRKRILMVHNVTGEDTGIYECVLNEDRMSLQLSLKDEAKFLNKPRGPMEVAP ALSGDLELNCEVSSASAVVVWRKDQTLVTEDQRTTVVSKGTQRRLVIKNAKKSDEGHYSC ETVEDKVTFQVKIKEAQQAVFYNKESVQKEVKVTLSQKATLSCEVSDPKTEVKWYKDGKL LTSTETVSTETKGRSRLLVVDKIEKKDAGEYTCEARAEKLVFKIHVSETQQSAFTNKESV QKEVKATLSQKATLSCEVSDTETEVKWYKDGKLLTSSKTVHMETKGKTRQLVIEKAEKKD AGEYTCEVGVEKLVYKIQVTEAQAVFTNKESVQKEVKATLSQKATLSCEVSDTKTEVKWY KDGKLLTSSKTVQMETKGKTRQLVIEKVEKKDAGEYTCEVGVEKLVYKIQVAEAQQSAFT NKDSVQKEVKATLSQKATLSCEVSDTKAEVKWYKDGKLLTSSKTVSMETKGKTRQLVIEK VEKKDAGEYTCEVGVEKLVYKIQVAEAQQSAFTNKDSVQKEVKATLSQKATLSCEVSDTK AEVKWYKDGKLLTSSKTVSMETKGKTRQLVIEKVEKKDGGEYTCEVGTEKLAYKIHVTGE TQAAFYNKESVQKEVKATLSQKATLSCEVSDTKTEVKWYKDGKLLTSSETVHMETNGKTR QLVIEKVEKKDAGEYTCEVGAEKLAFRIQTAETQAAFSNKESVQKEVKATLSQKATLSCE VSDTKTEVKWYKGGKLLTTSKTVHMETKDKTRQLVLDIVEKKDAGEYTCEVGAEKVAFKI QVAEVQAAFNNKESVQKEVKATLSQKATLSCEVSDTKTEVKWYKDGKLLTSSKTVQMETK GKTRQLVIEKVEKKDAGEYTCEVGAEKLAFRIQVAETTFSNKESVQKEVKATLSQKATLS CEVSDTETEVKWYKDGKLLTSSKTVSLETKGKTRQLVIEKVEKKDAGEYTCEVGAEKLAF KIEVAESSAKFKKTAVKSACSVQASEKIVLTTELTSESASVKWFRDGVELKESSKYDMKR EGHSHTLIVKSTEVKDSGTYSCHTADDKLEFKVQVKDSPLKFVVQLQPVATELGGTLTLT CEMNRALGDVLWRHNSCEVKPGGRFCVSTDGPKRVLTVTGMAKEDEGEYSCECKDDKTSA KVSTKAPRLVKLTSKLSNVAAVEGKEAIFKCSVTPADVNVKWFCNNVPITAGPKYKIEHG GTSHSLTVTSVSQDDAQEISIDAEGKTCSATLQVQLEPVMFKKKLENVMAVEEQKEVKLE VELSKPSKEVRWMKNSVVLQPGGNMEIRVDGAKQTLVFKSVTTADRGYYSCETLDDKTQA KLTVDVKKIEVVNGLLPEVKAHEKETVTLEVELSQADVEGSWTRDSVKLKAGSHCRITAL GKKHALTLSQIKMEDAGTIAFQAEGVKTSAKLIVTEPAAMISKPMEDVKAPEKEKATLEC EVSRTNAEVKWFKGDLELKPGKNFRIHSQGRTRSLLIHKCSQEDEGTYVCQTSDDNTSAK LTIHARDIKIVKRLEDVEVMEKESASFFCEISHDEVDCQWFKGDTKLKVGDNIKMRQEGK IYVLLFKSVTPEDIAEIKFTAEKASSTAKLTVKELPVQFVKKLRDKLALYTHRGFLECQV SRASAKVKWYKNKKEIKPSKKHEISSEGIYRKLTINDVGSDDEDTYTCDAIDDKTSCKLL VEEQAISVVRELSAVEVTEPFAAFFEVEINIDSVKPPKWTLNGVAVQESADVEMEKEGSM HRLTFKKTKASMTGPVQFMAGKSKSVAQLTVKERPLEVVEPIKDVTVKEKGSATLSCKFS ATPKEVSWFKGQTLLGASDKYSLKQDAVRAQLTIQKLTGEDTGDYRCQSAAAETKATLTV EVRKVEITKHLVDTEVDEDSDAVFICEINYTDEEVQWLLNEKALFSNEVNTITHVGKVHT LTLKNLAPEDGGTIIFKVREIKEGVTLKVKEKRAVFLKSLDDVVGEVKGMITLACEASKP RVSPTWRKDGTLLTTDSKYEVLHTGKSLGLIIKDVTKEDAGEYSCDLGTELSKSKVTVRD LSIGITKQLKSVEAMEGETCSFQCILSRESTDECSWTLNGQTVANGGRFQVSSTGRKYML VIKDVTPADAGEVVFNIKNLNSKTTLAVEGKAQSVSRELQSISVVSGEDAVFICEVTQTR ATVQWAKDGKDIRKSEKYEISKEERVMKLTVHSVTVQDSGEYSCEVIGGATTKAKLEIKE PVHKFTKELKDSEVEEEGSVTLQCETAQPASKATWSKDGVELKAGGRYEMSQKETVLTLT IKQLEEKDSGTYTCDVGTATMMAKVTVKALPASFEQKLKNQQAKEGESVTLCSVLSKPGA KVQWKKGTEHLKAGDKYEMKQKDASCELQIKHLNVEDSGEYSCECGDQRTTATINVNALP VTFKHKLESQEAEEGGNVTLHCELSKPGVPVEWRKGTQVLKSGEKYQLKQKESVSELLIS KVVPEDSGDYSCVCGDQKTTASLKIKAQLVTFKHKLESQEAEEGGSVTLHCELSKPGVPV EWRKGTQVLKSGEKYQLKQKESVSELLISKVVPEDSGDYSCVCGDQKTTASLEIKAQPVT FKQKLGSQEAEEGGNVTLHCELSKHGVPVEWRKGTQVLKSGEKYQLKQKESVSELLISKV VPEDSGDYSCVCGDQKTTASLKIKAQLVTFKHKLERQEAEEGGSVTLHCELSKPGVPVEW RKGTQVLKSGEKYQLKQKESVSELLISKVVPEDSGDYSCVCGDQKTTASLKIKAQPVTFK QKLGSQEAEEGGNVTLHCELSKPGVPVEWRKGTQVLKSGEKYQLKQKESVSELLISKVVP EDSGDYSCVCGDQKTTASLKIKALPVIFKQDLQSQEAEEGGSVTLHCELSKPGVPVEWRK GTQVLKSGEKYQMKQKDCSVDLQVCDLKPEDTGSYQCRTGDTESSACLKVNALPVIFTKE LQSQQAEEGGSVTLHCELSKPGVPVEWRKGEVGLCLCAKYNIIQEGHSARLVIQNLDPED SGSYTCDSGDRKTTAHLSVKALPVYFKTRLQNLEWDAGEIAILRCEITKPGASVVWSRGD RVLESNNKYQLKQEGAIVKLIIYSLQGADSGEYICDTGYQKTTSVLTVQEVEVTIVKVLN SCSVHEGEDVHFECHLSHDDAREVQWKLADVPLQNNEMNLIRAQGKVHSLTLRGVTQADS GTVTFTVGHHTSTASLTVRGAPVVFKKELESQEAVEGGSVSLTCEISADGKVTWRRGSVL LTQGEKYSMEHTGSTYILMVHKLKAEDAGEYTCDAGDKQSTATLTVKESVRITRELHDIT VTTGQDAVFACELSQEGVTNGEWWLGDNLLQNNDLNQMACQGRVHRLTLQMVTPDESGDV AFVVGEEKTVACLLVEDKPKALILEKPHDTVALEGETVTLSCTVSDPTATVTWSRNDVAI KAGLKYDLRKNGALLQLRIHNLEMEDSGTYCCDTGDAQCTVTLIVEGAPAFFQKELKNQE AQEGDDITLHCELSKAGTHVEWRKGGAILQAGKKYEMRQEGCVQELHIRNLEPEDNGYYT CDAGDQLTTALVAVQEPTVEVVSEMQDLRVAEDQPAEFICQYSRPVQAQWKRNGRPLEPD GRRVVVEQDWTVARLYISHVSTEDRGTYSCEAEGTCVVASLEVEAKPIEILQGLENMDTI DGGEALFECSISRCEIKDSCWLIDGKPVKDSPTTEIVSFESGRRHLLLLKDLHVGDNCKV TFQAGTAATSAMLNVKGWQLDVVRGLEDKVAVVGEKVEFSCVLTEPVPEAEVAWYSNGAE LKNDNTWAMQADGCFYQLVLRQAPAMPPQEITFAARDAISMAKLTVITFPDPPEDPELVS KHKQGVTLSWFTPLSDGGSPILGYRVEMRLADSALWLPCHAEPVCNTEFSVDNLIPGSGY RFRVAAINRAGTGEPVQLPQTVQLEAPITVIQQLACPGLQEGKMARVECQLSAEGSSVTW LRDNKELEFGVKYQVTIEGKTQVLLIKDFESADQGVYTCVASDEAESSINLNLPTGADGV KLEGAQPSLPPEAASEGDVHALWEALAKKRRMSREPTLDSISELPDEEDKEPKTPKEPVK EKKVPEKVNEKEKEKVVEPVIITKKKELDTNLHTSSEDESRVPTLVSYLKKSSKSSLSAS DQTESISTEKFYAQTSVQQTSVQQTTVLQTSSSGQQITAQTTEITGCGNEEDEEKGLLDA AVKIQAAFKGYKSCKDMCPVFKDVFKDQTKEPNGTIHLECVVEGKPDKVRWLKDGEPLVD SKHHHIDIYNDGTCSLVITAVTTKDTGIYTCEVTNKFGVTIHSGKVTVGSAREASGRRPL TMGYSADSEAESSSAESEMDESLRQASKRLRRLLRTRLPATSEEESFVSCDDEAELKAPE PKSYREDERYLYIRFDTRSEAQVASLHFQEMFTAQGMPVETTIQEAGPLKVELRIMKMGY TQDGSATPTQEKQLPAFMTGASAAPVFLTELQSQDVPEGYPVSFDCVVIGKPTPSMRWFK DGKLLEENDHYMINEEHEGCHQLIITTVLPSDMGVYRCMAENTSGIASTKAELRVDMSCS SDYDTAADATETGSYISAKGYMSRETEAFESMAEDEQIPQVLDELHDVHVSPGSPIAKMQ LKVKGFPAPRVYWFKDGIPLRSSDRILLLDKRGVHSLEVLEVKREDAGEYSAYISNAAGS AYSSARILVLGPGELTPVEEHDPKVPLVPPRFLEKFSNRKVKQGASVTLSVRVEGSPIPM VTWLKEESAEDVLWIKPDTKGYKVARSGRQHSLILMDAGSEHAGTYTCIATNRAGQSICT AHFEVEDAPRPKEETKIPLGITISPPVEDAGRRMPYLGEVGTEEFLMKLTSQITEMVSAK ISQDSAQNHQVLQWIEAWPKASTSLRVPGGDSDDETKTPSASPHHGRSRPSSILADSSSE SDDPDARGEMFDIYVATADYNPTIPNKETISLKEGQYVEVLDSAHPLKWLVRTKPTKTTP SRQGWVSPAYLDKKLKLSADAGDVPETGGEEVSEGEYKRRLLQLIQDMINSEAEFVKEMD FFTSHHVKQVESPDAPSDVTSQKEAIFRNIHEIKAFHSEFMFPKLRECDTDDDVAMRFLR SGEGFEKYLQYLVGQQKAEAAISDKTVHHFFKKYTDKQQASADPAEGPVLSINAYLQKPL DRIQKYKASLKELIRNKARNGQNCCLLEEAYAMVSSLPQRSENTHHVSMIENYPATLDVL GEPIRQGPFMMWEGAPGVRSSSRGHRRHAFLFKNYVVICKSKRDSNTDTQGYVFKNMMKL NNIDVNETVEGDDRAFEIWHEREDSVRKYTLQARTVIIKNSWLRDLRDLQQRYTMPGWSM PDFDELLADCTVELGQTVKLACKVTGVPKPVVTWYKDGHAVEADPHHIIIEDPDGSCTLI LDNMTADDSGQYMCFATSTAGNASTLGKITVQVPPRFVNKMRNAVFTVGEDAQFSCTIQS APSPKIRWFKEGRLLTDQERYQTYSESRSGVLVLVIKGPTERDLGHYECELSNRLGSARC AADLCLPSAVTRRGEQAITIEVTEQETKIPKKTIIIEETITTVVKNTRMKRRGLSPSGFN RSQTSTPDHQTTPTTRQRRQASTNRKTTIPTLYVTEPEGAAGARAAENKWVEVEEIIEYK VNKSPRPSRRGVSPAGSERAHTPSSTRPQRSANPNANNSNNNLVELQNHSELQGAQPLYW DDEEEDDDVAVDGSEVTPGISREAYEVSSLLIPNDHEHEEDEAWLEEQQEAFITEPDDNT PRKLEPKILTEGSRVLTLEDLEDYVPKEGETYGSSNTRSSPPERPCEISVLQREIGGSAV GQPVLLNVGRPVGMPRERPRPGFFSRFRDHLSGSMFSPAGPHHNYNHHPSGGQSRREIPI QVSHAKLEVKPLYCSEVQRVEGVQQSYKTKVYTSVGKSVTLQISKNNPYQNQ NT seq 20139 nt NT seq  +upstreamnt  +downstreamnt atggaccagaacctgtttggaggggcccccagattcctcacgcggcccaaagcgttcgca gtgtgcgtgggcaaggatgccactctaagctgcaccatcgtgggcaaccccaccctactg attacctgggaaaaggagaagctacgtctgacctccgggggccgcttcaagacggtggat gatggtaatgtctaccgcctcaccatctacgatctaaccctggaagacagcggtcagtac atgtgccgggccaagaacaacgtcggggaggcatacgcatgtgtaacccttcatgtaggc cttccacaggagatggtggacagggcccccgtcttcatggtcaagcctacctctgcacgt gtgggcctggggggcgatgtggtcttccactgccgggttgctgcttacccagagcccaaa tttgactgggataaggacgggcgttacctagccgagacaaaccgcatcaaggtgtcctcg gacggcgacagcagctccctgaggatccagagcgtgcgcagcctagacagcggcacttat acctgccgcgcccagaactcggtgggccgctcgaactctgccgctgccttggtcatagac acccaggactcccgtcacctgggccaggacaagagcacctccctcctctcccacatgcag aagcgtaaagaagggatctccatctaccgcacagcagagacccgcagctcctctcacaac tccaccaccacctcgtccacggccaccactatggtcacagacgggctgagcgctctgggt ctggaccacggcagcgcagcactggtcagccagctacccaaaagcgtcttcacccgcacc tgcacggtgactgagggcaagcatgccaagctcagctgcttcgtgacgggtcaccccaag cctcatatcatctggaggaaggatggggggaacatcggcgagggacgtaggcacatcatg tatgaggaccaggctgagaatttcatcctcaagatcctgtactgcaagcagagcgacaac ggcctgtacacctgtaatgcctccaacatggctggacaaacctacagcgctgtgctggtg attgttaaagagcccaaggtgccgttcaggaggaagctgcaggatgtggaggtccaggag aagatgacggcgatgctgctgtgtgaggtgcccgtttcggctagccaggccagctggttc atggaggagacacgtctggaggacagctccaagtactgcatggaggaggaggggaccatg cgtcgcctcaccatccgcaatgtcaccactaatgatgatgccgtctacatctgcgagatg aaggaggggagccgcaccgtagccgagctcactgtgctggggaacatcactaagaagctt cccaggaggactgtagtgtcggtgagtgatacagtgatcttctgcgtggagctggagcac ccctgttctgacgcctactggacgcgcaacggcgagcgcctgaagccggacacacggata tccattgcgtgcaccctcagacagtacacgctaaccatcagccactgccaggccgacgac tcaggagaggtggcttttgtggctggagactgcaagacctccacacgattctcagtcacg gctgccagaaagcaccctccagatccccctatcgacgtggtggtgcgtaacaagaccgac tcgtccatcaccctccactggtcccccccagacagtgaccgccccgtgcccatcaaaggg tacatggtagagaggaggaaggtgggtgcccagacctggcagaggtgcaacggcatggaa gtcagcccctttactgagatcacgatccagaatatcacagaggaggccagctaccagttc cgcatctccgcagtcaacgactacggccagagccagtatgtggaggtgcctgggaccttc tacctcgagccctctgcagaggtgaagacaggcctgatgaacagcacagccatctcaggc gaggaggcctccctctccgtggacctgtctgccgtgtgctctggctcctggtctatcaac ggccgcctcctgcggagtggggctgactacctcatcacacgccaaaagaccacacatacg ctgacgatccgaaccgtctcgatggagatgaatggagccgcggtcaaatttgtgggcggt ggctccgagagctcttgtatactccacgtgaaggctccagctgtccggttcaccagtaag tccgctcacaccgaggtggtgacctgcagcgcccagtcctccgcccagctgaccacagag gtgtccgattatgatgctcaggtggtctggatgaagaatggacgggagctgaaggtgggc aagaagtatgagtgcataagcaccgaccgcaagaggatcctgatggtgcacaacgtcacc ggagaggacacgggcatctatgagtgtgtcttaaacgaagaccgaatgtccctgcagctt tctctaaaagatgaagccaagttcctgaacaagcccaggggtcccatggaggtggcgcct gccctcagcggggacctggagttgaactgcgaggtgtcgtctgcaagcgcggtggtggtg tggaggaaggatcagacactggtcaccgaggaccaaagaaccaccgtcgtctccaaaggg acacagaggagactggtcatcaagaatgccaagaagagtgacgagggacactactcctgc gagacagtcgaggacaaagtcacattccaggtcaagatcaaagaagcccaacaggcagta ttctacaacaaggagtctgtacagaaggaggtgaaagttactctctcccagaaagccact ctgagctgtgaagtgtccgacccaaagactgaggtgaaatggtacaaggacggcaagctg ctgacttccactgagacagtctccacggagacaaagggcaggagtcgtctgttggtagta gacaaaattgagaagaaggatgctggagaatacacctgtgaggctagagcagagaagctg gtctttaaaatacatgtttcagaaacccaacagtctgctttcaccaacaaggagtctgta cagaaggaggtgaaagctactctctcccagaaagccactctgagctgtgaggtgtctgat accgagacagaggtgaaatggtacaaggatggcaagctgctgacttccagtaagacagtc cacatggagacaaagggcaagactcgtcagctggtgatagagaaggcggagaagaaggat gctggagagtacacctgtgaggttggagtggagaaactggtctataagattcaggtgaca gaagcccaggctgtcttcaccaacaaagagtctgtacagaaggaggtgaaagctactctc tcccagaaagccactctgagctgtgaggtgtctgataccaagacagaggtgaaatggtac aaggatggcaagctgctgacttccagtaagacagtccagatggagacaaagggcaagact cgtcagctggtgatagagaaggtggagaagaaggatgctggagagtacacctgtgaggtt ggagtggagaaactggtctataagattcaggtggcagaagcacaacagtctgccttcacc aacaaggactctgtacagaaagaggtgaaagctactctctcccagaaagccactctgagc tgtgaggtgtctgataccaaggcagaggtgaaatggtacaaggatggcaagctgctgact tccagtaagaccgtctccatggagacaaagggcaagactcgtcagctggtgatagagaag gtggagaagaaggatgctggagagtacacctgtgaggttggagtggagaaactggtctat aagattcaggtggcagaagcacaacagtctgccttcaccaacaaggactctgtacagaaa gaggtgaaagctactctctcccagaaagccactctgagctgtgaggtgtctgataccaag gcagaggtgaaatggtacaaggatggcaagctgctgacttccagtaagaccgtctccatg gagacaaagggcaagactcgtcagctggtgatagagaaggtggagaagaaggatggtgga gagtacacctgtgaggtgggaacagaaaagctggcctacaagatacacgtgactggagaa actcaggctgccttctataacaaggagtctgtacagaaggaggtgaaagctactctctcc cagaaagccactctgagctgtgaggtgtctgataccaagacagaggtgaaatggtacaag gatggcaagctgctgacttccagtgagacagtccacatggaaactaatggcaagactcgt cagctggtgatagagaaggtggagaagaaggatgctggagagtacacatgtgaggttgga gcagagaaactggccttcaggattcagacggcagaaactcaagcggctttctccaacaag gagtctgtacagaaggaggtgaaagctactctctcccagaaagccactctgagctgtgag gtgtccgacaccaagacggaggtgaaatggtacaagggcggcaagctgctgacaaccagc aagacagtccacatggagacaaaggacaagactcgtcagctggtgttggacattgtggag aagaaggatgctggcgagtacacctgtgaggttggagcagagaaagtggcctttaagata caggtggcagaggtccaggcagccttcaacaacaaggagtctgtacagaaggaggtgaaa gctactctttcccagaaagccactctgagctgtgaggtgtctgataccaagacagaggtg aaatggtacaaggatggcaagctgctgacttccagtaagaccgtccagatggaaactaag ggcaagactcgtcagctggtgatagagaaggtggagaagaaggatgctggagagtacacc tgtgaggttggagcagagaaactggccttcaggatacaggtggcagagactaccttctcc aacaaggagtctgtacagaaggaggtgaaagctactctctcccagaaagccactctgagc tgtgaggtgtctgataccgagacagaggtgaaatggtacaaggatggcaagctgctgact tccagtaagacagtctccttggagacaaagggcaagactcgtcagctggtgatagagaag gtggagaagaaggatgctggagagtacacctgtgaggttggagcggagaagttggccttc aagatagaggtggcagaatcctctgccaagtttaaaaaaactgcagtgaagagtgcatgc agtgttcaagcaagtgagaagattgttttgaccactgagttgacttcggagagtgccagc gttaagtggttcagggacggtgtggagttgaaggagagctctaagtatgacatgaagaga gagggacattctcataccctgattgtgaagtccactgaagtcaaagacagtggcacctac tcttgccacactgctgacgacaagcttgagttcaaagttcaagtcaaagactcaccgctg aagtttgtggtgcagttgcagcctgtagccacagagctgggtggtacactgacactgacc tgtgaaatgaaccgagccttaggggacgtgctctggcgccacaacagctgtgaggtcaaa cccggcggcaggttctgtgtcagcactgatggtcccaagcgggtccttactgtgacagga atggcaaaagaggatgagggagaatacagctgtgaatgcaaagatgataagacctccgcc aaggtctccaccaaagcacccagactggtgaagctgacttccaagctgagcaacgtcgct gctgtggaggggaaggaggccatcttcaagtgtagtgtcaccccagctgacgtcaacgtg aaatggttctgcaacaacgtgcccatcactgctgggcccaaatataagattgagcatggg ggcaccagccactccctcaccgtcacctcagtcagtcaggatgatgctcaagagatcagc attgatgcagagggcaaaacctgcagtgctaccctccaagtgcaactggagccggtgatg ttcaagaagaagctggagaatgtgatggcggtggaggaacagaaggaggtgaagctggag gtagagctgagtaagccctctaaagaggtcaggtggatgaagaacagcgtggtgctacag cctggaggcaacatggagatcagggtggacggagccaagcagaccctggtctttaagagt gtgactacggcagaccgtggttactactcctgtgagaccctggacgacaagacccaggcc aaactcacagtggatgtgaagaagattgaggtggtgaacggcctgctgccggaggtcaag gcccatgagaaggagacagtgacccttgaggtggagctcagccaggctgacgtggagggc tcctggaccagggacagcgtcaagctcaaggcagggtcacactgccgcatcacggccctg ggaaagaagcacgccctcacactatcccaaattaagatggaggacgcaggaacaattgct ttccaagcagagggagtcaaaacttctgccaaactcattgttacagaacctgcggctatg atctctaaacccatggaggatgtcaaagccccagagaaggagaaggctacgcttgagtgt gaggtgtccagaactaatgctgaggtcaagtggttcaagggtgacttggaactgaaacca ggaaagaactttcgcatccactcccaggggcgcacacgcagcctgctaatccacaaatgt tcccaagaggatgagggcacatacgtctgccaaacgtctgatgacaacacatcagctaaa ctcactattcacgcccgagacattaaaatagtgaagaggcttgaggacgtggaggtgatg gagaaggagagcgcttcgttcttctgtgagatctctcacgatgaagtggactgccagtgg ttcaaaggcgacaccaaactcaaagtcggtgacaacatcaagatgagacaagagggtaaa atctatgtgctgctgtttaagtcggtgaccccagaagacattgctgagattaaattcaca gctgaaaaggcttcttcaacagccaaactgacagtgaaagagctccctgtccagtttgtg aagaagctcagggataagttagccttgtatacacaccgtgggttcttggaatgccaagtg tcccgggccagcgccaaggtcaagtggtacaagaacaagaaggagatcaagcccagcaag aagcacgagatcagcagcgagggtatataccgcaaactcaccataaacgacgtgggctcg gatgatgaggatacttacacctgtgacgccatcgacgacaagacatcctgtaaacttctt gtggaagagcaggccatcagcgtcgtacgggagctaagtgccgtggaagtgaccgagccc tttgccgccttcttcgaggtggagatcaacatcgactcagtcaagccccccaagtggacc ctgaatggtgtggccgtgcaggagagcgctgacgtggagatggagaaggagggctccatg caccgcctcaccttcaagaagaccaaggcctccatgacaggacctgtccagttcatggct ggcaagagcaagtctgtggcccagcttactgtcaaagagcgtcctcttgaggtggtagag cccattaaagatgtgacagtcaaggagaagggctcagccactctgagctgcaagttctcc gccacacccaaagaggtgagctggttcaaagggcaaaccctcctgggtgcttcagacaag tacagcctgaaacaggacgctgtgagggctcagctgaccatccagaagctgactggggaa gacactggggactaccgctgtcagtcggctgctgccgagaccaaagccactctcactgta gaggttcggaaagtggagatcaccaaacacctggtggacacagaggtggacgaggacagt gatgcagtgttcatttgtgagatcaactacactgatgaggaggtgcaatggctactcaat gaaaaagcactcttctccaacgaggtcaacaccatcacacacgtgggcaaagtgcacacg ctcacactcaagaatctggcacctgaggatgggggcaccatcatcttcaaggtcagggaa atcaaggagggcgtgaccctaaaagtcaaagagaagcgtgcagtgttcctcaagtctctg gatgacgtggtgggagaggtgaaaggtatgatcaccctggcgtgtgaggcctccaagccc agggtctcccccacctggaggaaagatggtacgctcctgaccactgactctaagtatgag gtcctgcacacaggcaagtccctgggtctgatcatcaaggatgttaccaaggaagacgca ggggagtacagctgcgacctgggtactgagctttccaagtcaaaggtcactgtgagagac ctgagcataggtatcaccaaacagttgaagtccgtggaggcgatggagggagagacatgt agctttcagtgtattctgtcacgggaaagcactgacgagtgttcctggaccttgaatggc cagaccgtggctaacggaggacgcttccaggtctccagtacaggtcgcaagtacatgctg gttatcaaggatgtgacgccagccgatgctggtgaggtggtcttcaacataaagaacctg aactccaagactaccttagctgttgaaggcaaagctcaatctgtatcacgggagctgcag agcattagtgtagtttcaggggaggatgctgtgttcatctgtgaggtcacacagaccagg gccaccgtccagtgggccaaagatgggaaggacatcaggaagagtgagaagtatgagatc agtaaagaggagagggtcatgaagttgaccgtccacagtgtcactgttcaggactctggg gaatatagctgtgaggtcatcggaggggccactaccaaggccaagctggagatcaaagag ccagtccacaagtttaccaaggagcttaaggacagcgaggtggaggaggagggctcagtg accctgcagtgtgagacggcccagcctgcctccaaggccacctggtccaaggatggcgtg gagctgaaggccgggggacgctatgagatgagtcagaaggagaccgtcctcaccctcact atcaaacagctggaggagaaagacagcggcacttacacctgtgacgtgggcactgccacg atgatggcgaaggtgacagtcaaagccttgcctgccagctttgaacaaaagctgaagaac cagcaggccaaggaaggggagagtgtcactctctgctctgtgttatccaaacctggggcc aaggttcagtggaagaaaggcactgagcatctcaaagctggagacaaatatgagatgaaa caaaaagatgcctcctgcgagcttcagataaagcatctgaatgttgaggacagtggggag tactcctgtgagtgtggagaccagaggaccacagcgactataaacgtcaatgcgttacct gtgaccttcaaacacaagctggagagccaggaggctgaggaggggggcaatgttaccctg cactgtgagctctctaaacctggagtccctgtggaatggaggaagggaacacaggtgctg aagtctggagaaaagtaccagctgaagcagaaagaatctgtgagtgaactcctgatcagc aaagtagtaccagaggacagtggagactacagctgtgtgtgtggagaccagaagactaca gccagtctcaagattaaggcccaacttgtgaccttcaaacacaaactggagagccaggag gctgaggaggggggcagtgttaccctgcactgtgagctctctaaacctggagtccctgtg gaatggaggaagggaacacaggtgctgaagtctggagaaaagtaccagctgaagcagaaa gaatctgtgagtgaactcctgatcagcaaagtagtaccagaggacagtggagactacagc tgtgtgtgtggagaccagaagactacagccagcctcgagattaaggcccaacctgttaca ttcaaacaaaagctagggagccaggaggctgaggaggggggaaatgttaccctgcactgt gagctctctaaacatggagtccctgtggaatggaggaagggaacacaggtgctgaagtct ggagaaaagtaccagctgaagcagaaagaatctgtgagtgaactcctgatcagcaaagta gtaccagaggacagtggagattacagctgtgtgtgtggagaccagaagactacagccagt ctcaagattaaggcccaacttgtgaccttcaaacacaaactggagagacaagaggctgag gaggggggcagtgttaccctgcactgtgagctctctaaacctggagtccctgtggaatgg aggaagggaacacaggtgctgaagtctggagaaaagtaccagctgaagcagaaagaatct gtgagtgaactcctgatcagcaaagtagtaccagaggacagtggagactacagctgtgtg tgtggagaccagaagactacagccagtctcaagattaaggcccaacctgttacattcaaa caaaagctagggagccaggaggctgaggaggggggaaatgttaccctgcactgtgagctc tctaaacctggagtccctgtggaatggaggaagggaacacaggtgctgaagtctggagaa aagtaccagctgaagcagaaagaatctgtgagtgaactcctgatcagcaaagtagtacca gaggacagtggagactacagctgtgtgtgtggagaccagaagactacagccagtctcaaa attaaggctctcccagtcatattcaaacaagatctgcagagtcaggaggctgaagagggg ggcagtgttaccctgcactgtgagctctctaaacctggagtccctgtggaatggaggaag ggaacacaggtgctgaagtctggagaaaagtaccagatgaagcagaaagattgcagtgtg gacctccaagtctgtgatttgaaacccgaagacacagggagctaccagtgcaggactgga gacacagagagctcagcatgcctgaaagtcaatgctctcccagtaattttcactaaagag ctgcagagccaacaggctgaggaggggggcagtgttaccctgcactgtgagctttctaaa cctggagtccctgtggaatggaggaagggggaggtgggtctttgcctctgtgccaagtat aacatcatccaggaagggcacagcgctaggctagtcatccaaaacctagacccagaagac tcaggcagctacacctgtgacagtggtgaccggaaaaccacagcacacctttctgtgaag gccctgcccgtttacttcaaaactcgactacagaatctagagtgggacgcaggtgagatc gccatcctccgctgtgagatcaccaagcctggggccagcgttgtctggagccggggcgac agggtcctggagtctaacaacaagtatcagctgaaacaggaaggggccattgtgaagctt atcatctatagcctacaaggggctgactctggggagtatatctgtgacacaggttaccag aagaccacctccgtgctcactgtacaggaggtggaggtgaccatagtgaaggtcttgaac agctgttcggtgcacgagggggaggatgtccactttgagtgccatctgtcccacgatgac gccagggaggtccagtggaagcttgcggacgtccctctgcagaacaatgaaatgaacctg atccgtgcccagggcaaggtgcacagcctcaccctcaggggggtcacccaggccgactcg ggcacagtcaccttcaccgtgggtcaccatacctccaccgcaagcctgaccgtccgaggg gcccctgtggtgttcaagaaggagctggagagccaggaagcagtggagggaggcagtgtt tctctgacctgtgagatcagtgctgatggcaaggtgacctggagaaggggctccgtgctc ctcacccagggggagaagtattccatggagcacacaggttctacctacatcctgatggtt cacaagttaaaggctgaagatgctggagagtacacctgcgatgccggggataagcagagc acagccaccctgacagtcaaagagtctgtgcgcatcactcgggagctgcacgacatcaca gtgaccaccgggcaggatgctgtctttgcgtgtgagttgtcccaggagggcgtgaccaac ggagagtggtggctgggcgataacctcctccagaacaacgacctgaaccagatggcctgc cagggccgggtacaccggctgacactacagatggtcacccccgatgaatcaggggacgtg gcgtttgtggtgggcgaggagaagaccgttgcttgcctactggtggaagataagcccaaa gccttaatccttgagaagcctcacgatacagtggccttggagggcgagacagtcaccctg tcctgcactgtctccgaccccacggccaccgtcacctggagcaggaatgatgtggccatc aaagcaggactcaagtacgacctgcggaagaatggagctctcctgcagctgcgcatccac aacctggagatggaggactctggaacttactgctgcgataccggggatgcacagtgcacc gtcaccttgattgtggaaggtgccccggcattctttcagaaggagctgaagaaccaggaa gcccaggagggtgatgatatcactctgcactgtgagctctccaaggcgggcactcacgtg gagtggaggaagggaggcgcaatcctccaggctggtaagaagtacgagatgaggcaggag ggctgcgttcaggagctccacattcgcaacctggagccagaggacaacggctactacacc tgtgatgctggagaccagctcaccacggcattagtggcagtgcaagaacccacagtagag gtggtgagtgagatgcaggacctccgtgtggctgaggaccagccggctgagttcatctgc cagtactcccggccggtccaggcccagtggaaaagaaacgggagaccgttggagcctgac ggcaggagggtggtagtggagcaggactggaccgtggcccgcttgtacattagccacgtg tccactgaggacagggggacgtactcctgtgaggcagaggggacctgcgtggtcgcctcc ctggaggtggaagccaaacccattgaaatcctccagggcctggagaacatggacaccatc gacggcggcgaggccctgttcgagtgctcgatctctcgttgcgagatcaaagacagctgc tggctcattgacggcaagccggtgaaggattcgccaaccactgagattgtgtccttcgag agtggccgccgccacctgctgctgctaaaggacctgcacgtcggggacaactgcaaagtg accttccaggcgggcaccgcagcgacctccgccatgctcaacgtcaaaggctggcagctg gatgtggtgaggggtctggaggataaggtagctgtggtgggagagaaagtagagttcagc tgcgtgctgaccgagcctgtgcctgaggcggaggtagcctggtactctaacggagccgag ctaaagaatgataacacctgggccatgcaggctgacggttgcttctaccaactggtgctg agacaggccccagccatgccaccacaggagatcacctttgctgccagggacgccatttcc atggccaagctcactgtcatcacctttccagaccccccggaggacccagagctggtcagt aagcataaacagggggtgaccctgtcctggttcacacctctcagcgatggaggcagcccc attctgggttacagggtggagatgaggctggcagacagcgccctctggcttccgtgccat gcagagcctgtgtgtaacacagagttctctgtggataacctcatcccagggagcggctac aggtttagggtggcagccatcaacagagctgggactggagaacctgtccagctgcctcag accgttcagctggaggctccgatcacagtgatccagcagttggcctgtccaggcttgcag gagggtaagatggcccgtgtagagtgccagctctctgctgagggcagctcggtcacctgg ctcagagacaacaaggagctggagtttggggtcaaataccaggtcaccatcgagggcaag acacaagtgctgctgatcaaagactttgagtctgctgaccagggagtgtacacctgtgta gcctcagacgaggcagaaagctccattaatctcaatttaccaacaggtgctgatggggtt aagttggagggggcccagcccagcctgcctcctgaggctgcctccgagggagatgtccat gcgctgtgggaggccctggccaagaaacgccgcatgagccgagagcccaccctcgactcc atctctgagctgcctgatgaggaggacaaggagcccaaaacacccaaggagccagtcaag gagaagaaagtcccagagaaggtgaacgaaaaggaaaaggagaaggttgtggagcctgtc atcatcacaaagaagaaggagttggataccaatctacacaccagctctgaggatgagtcc agggttccaacgctggtgtcctacctgaagaagagcagcaagtcctccctctctgcatcc gaccagacagagtccatctcaactgagaagttctatgcacagacctcagtgcaacagacc tcagtgcaacagaccacagtcctacagacctcatcttcaggacagcagatcacagcacag accacagagatcactgggtgcggaaatgaggaggatgaagaaaaggggctgctggatgct gctgtcaagatccaggctgcgttcaagggctacaagtcctgcaaggacatgtgtccagtc ttcaaggacgtcttcaaggaccagaccaaggagcccaatggcaccatccacctggagtgt gtggttgagggaaagcccgacaaggtgcgctggctgaaggacggcgagccccttgtggac agcaaacaccaccacatcgacatctacaacgatggcacctgctctctggtaatcaccgcc gttaccaccaaggacacaggcatctacacatgtgaggtcaccaacaagttcggcgtgacc atccacagcggcaaggtgacagtaggctcggcacgggaggcatctggaaggaggcccctg accatgggctacagcgccgacagcgaggcggagagctcgtctgcagaaagcgagatggac gagtctttgaggcaggccagcaaacggctgcgccgcctcctccgcacacggctgccggcc acgtcggaggaggagtcgttcgtcagctgtgacgatgaggctgagctgaaggcccccgag cccaaatcgtaccgtgaggacgagcgctacctctacatccgctttgacacgcggtctgag gcccaggtggcgtcgctgcactttcaggagatgttcacggcccaggggatgcctgtggag accaccatccaggaggctggacctctcaaagtggagctgcgcatcatgaagatgggatac acccaagatggctctgcaacacccacacaggaaaagcagctgcccgcgttcatgacagga gcctccgcggccccagtcttcctgaccgaactccagagccaggacgtgcctgaaggttac ccggtcagctttgactgcgtggtgatcggaaagcctacacccagcatgcgttggttcaag gacgggaagctcctggaggagaatgaccactacatgatcaacgaggaacacgagggatgc caccagctcatcatcaccaccgtgctgccttctgacatgggtgtctaccgctgcatggct gagaacaccagtggcatcgcttccactaaggctgagctcagggttgacatgtcttgcagc tcagactacgatactgcagctgatgccactgagacaggctcctacatcagcgccaagggc tacatgtctagggaaaccgaagcgtttgagtctatggcagaggatgagcagataccacaa gtactggatgagctccatgatgtgcacgtcagcccaggctcacccatcgctaagatgcag ctgaaagtcaaaggtttccccgcgcccagagtgtactggttcaaggacggtatcccgctg cgttcctcagacaggatcctgctgctggacaagagaggcgtccacagtctggaggtcctg gaggtgaagagggaggatgcaggagagtactctgcctacatcagcaacgctgctggatca gcatactcctctgctaggatactggttctgggtccaggagagctcacacctgtagaagag cacgatcccaaggtgcctctggtgccgccacggttcctggagaagtttagcaacaggaag gtgaaacagggagccagtgtcaccctgtcagtcagagtggaaggttctcccatccccatg gtgacgtggctgaaagaggagtctgctgaggacgtgttgtggatcaagccagacactaag ggatataaggtggccaggtctgggcgccaacacagcctcatcctcatggatgcgggttct gagcacgccggcacctacacctgcatagccaccaacagggccggccagtccatctgcact gcccactttgaagtagaggatgcaccacgaccaaaggaagagaccaaaatccctctgggt attactatcagccctccagtggaggatgctggcagaagaatgccttatctaggtgaagtt ggaacagaagagtttcttatgaaactcacctctcagatcacagagatggtatctgccaag atcagccaagacagcgcacagaaccatcaagtgctccagtggattgaagcatggcccaaa gcctccacctcactacgtgtcccgggaggcgatagcgacgatgagaccaaaacaccctcc gcctcgccccatcacggccgctctcgccccagctccattctcgcagattcctcctctgag tctgacgaccctgatgccaggggagagatgtttgacatctatgtggctacggctgactac aaccccaccatccccaacaaagagaccatttccctgaaggagggccagtatgtggaggtt ctggactcggcacatccactcaaatggctggtccggaccaaaccaaccaaaaccacccca tcccgccagggctgggtgtcacctgcatacctggacaagaaactcaagctgtctgctgat gctggtgatgtcccagagacgggtggagaagaggtctcagaaggagagtacaaaagaaga ctactccaactgatccaggacatgatcaacagcgaggcagagtttgtcaaagagatggac ttcttcacctcccaccacgtcaagcaggtggagagccctgacgccccatctgacgtcacc agccagaaggaggccatattcaggaacatccatgagatcaaggccttccatagcgagttc atgttccctaagttgcgcgagtgcgacactgatgacgacgtggccatgcgcttcctgagg agcggggagggctttgagaaatacctccagtacctcgtaggccagcaaaaggcagaggcc gctatcagtgacaagaccgtacaccatttcttcaagaagtacacagacaaacagcaggcc agtgccgaccctgctgaagggcctgtattgagcattaatgcctacctacagaaacccctg gacagaatccagaagtacaaggcctcgctcaaggagctgatcaggaacaaggcccggaac ggtcagaactgctgcctgctggaggaggcctatgccatggtttcatcactgcctcagcgt tcagagaacacacaccacgtctccatgatagagaactaccctgccactctggatgtattg ggggagcccatcagacagggacccttcatgatgtgggagggtgcacctggggtaaggtcc tcctccagaggccaccgtcgacacgcgttcctcttcaaaaactatgtcgtcatctgcaaa tccaagagagactccaacacagacacccagggctacgtctttaagaacatgatgaagctg aacaacatagacgtgaatgagacagtggagggtgacgaccgggcctttgagatctggcac gagcgcgaggactctgtcaggaagtacacgcttcaggctcgcaccgtcatcatcaagaac tcctggctgcgagacctcagggacctgcagcagcgctataccatgcccggctggagtatg cctgactttgatgagcttctggctgactgcacagtggagctgggacagacagtgaaactg gcctgcaaggttactggagtacccaaacctgtagtcacctggtacaaggatgggcatgcg gtggaggctgacccccaccacatcatcatcgaggaccctgacggttcctgcaccctgatc ctggacaacatgacagcggacgactctggacagtacatgtgcttcgccactagcaccgca ggcaacgccagcaccctggggaagatcactgtccaagtgcctcctcgttttgtgaacaag atgaggaatgctgtctttaccgttggtgaggatgctcagttctcctgcaccatccagagc gctcccagccccaagatcaggtggttcaaggagggcaggctgctgactgaccaggagagg tatcagacctacagtgagtcccgtagtggagtactggtcctagtcattaaaggccctacg gagagagacctgggacattacgaatgtgagttgtctaatcgactgggcagtgctaggtgt gcagctgatctgtgccttccttctgctgtgactaggagaggagagcaggcgatcaccatc gaagtcaccgagcaggagactaaaataccaaagaaaaccatcatcatagaggagaccata accacggtggtgaagaacacccgtatgaagcgtcgtggcctgtctccatctgggttcaac cgctcccaaacctccaccccagatcaccagaccacccccacgaccaggcagaggaggcag gcttccaccaacaggaagaccaccatccccaccctgtacgtcacggagcccgagggggcc gcaggggcccgggctgcggagaacaagtgggtggaggtagaggaaatcattgagtacaag gtcaacaagtcgcccaggccctccaggagaggtgtctccccagccgggtcggagcgggca cacaccccctcctccacccggccacagaggtctgcaaaccctaacgccaacaactccaac aacaaccttgtagaactgcagaaccactccgagctacagggggcacagcctctgtactgg gacgatgaggaggaggatgatgacgtggctgtggatgggtccgaggtcacccctggaatc agtagagaggcctacgaggtctcctcgcttctaattcctaacgaccatgaacacgaagag gacgaggcctggctagaagagcagcaagaggctttcatcacagaaccggatgacaacaca cccagaaagctggagcctaaaatcctgaccgagggcagtcgcgttctcaccctggaggac ctggaggactacgtccccaaggagggggagacctacggctcctccaacacccgttcatca cctcccgagaggccctgcgagatctcagtgctccagagggagattgggggctctgctgtg ggccagccggtgctgctcaacgtagggaggcctgtggggatgcctagggagaggcccagg ccgggcttcttcagccgctttagagatcacctctcaggaagcatgttctccccggccggc ccccaccacaactacaaccaccaccccagcggaggtcagtccaggagggagattcccatc caggtcagccacgccaagctagaggtcaagccgttgtactgctctgaggtgcagagagtg gagggagtgcagcagagctacaaaactaaagtctacacgtcagtgggcaagtcagtcact cttcagattagcaagaataacccatatcaaaaccaataa

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