Oncorhynchus nerka (sockeye salmon): 115144409
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Entry
115144409 CDS
T07952
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit-like isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
one
Oncorhynchus nerka (sockeye salmon)
Pathway
one00270
Cysteine and methionine metabolism
one00480
Glutathione metabolism
one01100
Metabolic pathways
one01240
Biosynthesis of cofactors
one04216
Ferroptosis
Module
one_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
one00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
115144409
09106 Metabolism of other amino acids
00480 Glutathione metabolism
115144409
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
115144409
Enzymes [BR:
one01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
115144409
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Motif
Pfam:
GCS
GCS2
HasA
DUF2811
Motif
Other DBs
NCBI-GeneID:
115144409
NCBI-ProteinID:
XP_029541297
EnsemblRapid:
ENSONEG00000040788
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Position
LG16:29643519..29651600
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AA seq
630 aa
AA seq
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MGLLSKGSPLNWEETKKYADHVRKHGIVQFLNIYNKVKERQKDVLLWGDEVEYMLIEMDE
KNGKVRLVLNGGEVLETLQDKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSVLNKNETLATITSFPRLGCPGFTQPEYKPTPVEKGVSKSLFFPDEAI
NQHPRFSTLTRNIRHRRGEKVVINVPIFKDKYTPSPFVEKFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIEEARYLYDQLATFCPIMMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTGEERGLEPLKTNKFRILKSRYDSIDSYLSSCGDRYNDIDLTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSLFEEKIYLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAFVVFIVLLTRVILSYKLDFLIPLSKVDENMKAAQKINAV
QEGMFYFRKDIYKGCNPALDSSSSAAQNGLDSEGDNEYTLMSIDTIINGKEGIFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKRRASGELMTMAKWMREFVDKHPQYKQDSVITDRI
NYDLLRKCDSITKGEERCPELIGDPVNRGK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcaaaagggtcaccgctcaactgggaagaaaccaaaaagtatgcagac
catgttcggaaacatggcatcgttcagtttctcaacatttataacaaggtgaaagaacga
cagaaagatgtcttattatggggcgatgaggtggaatacatgttgatcgaaatggatgag
aaaaatggaaaggttcgtcttgttctcaatggtggggaggttttggaaacccttcaagac
aaaggagaaaagaccaaccccaaccatcctaccctttggaggccagagtatggcagctac
atgatcgaagggactccggggcagccctacggtgggacgatgtcagagttcaacacggtg
gaggacaacatggggaagaggaggcgagaggcctcatctgtgctgaataagaatgaaacg
cttgccaccatcacgtcattcccaaggttaggctgcccaggcttcacacagccagaatac
aagccaacacctgttgaaaagggagtgtcaaaatcactgttcttcccagatgaagccata
aaccaacacccaagattcagcaccctgaccagaaacattcgtcacagaagaggagagaag
gtggtgatcaacgtacccatctttaaagacaaatacaccccatctccatttgtggagaag
tttccggaagacgatggggaggctgccagggcagctctacctgatcacatctacatggat
gccatgggatttggaatgggcaactgctgtcttcaggtgacattccaagcttgcagcatt
gaagaggcgaggtacctttatgaccaactagcaacattctgccctataatgatggccctc
agtgctgcttcgccgttctacagaggctatgtgtcagacattgattgtcgctggggagtt
atttctgcctcggtagatgacaggaccggggaagagagggggctggagcctttgaaaacc
aacaaatttcgaatcttgaaatccagatatgattcaatcgacagctacctctccagctgt
ggcgataggtacaatgacatagatctgacaatagacgaggagatcaacaaacagctgctg
gatgcagggatcgacaaactgctggcccaacacatagcccatctcttcattcgggatccg
ctctcactatttgaagagaaaatttacttggatgatgaaaacgagtctgatcactttgag
aatctgcagtcaaccaactggcagacaatgaggttcaaacctcctcctccaaactcggac
atcggatggcgagttgagttccgtcccatggaggtgcaacttaccgattttgaaaactct
gcattcgttgttttcatcgtccttctcaccagggttatactgtcctataaactggacttt
ctcatccccttgtcaaaggttgacgaaaacatgaaagctgcccagaaaataaatgcagtc
caagagggcatgttttacttccggaaggacatctataaaggctgcaaccctgccctcgat
agctcctcatcggctgcccagaatggcttggacagtgagggtgacaatgagtacacactg
atgagcattgacacaatcatcaatggaaaggaaggaatttttcaagggttgataccaatc
ctcaactgctacctagaaaacatggaggtggatgttgatacaagatgcaccatcctgaac
tacctgaagctcatcaagagacgtgcctccggtgaactgatgaccatggctaaatggatg
agggagtttgtggacaagcacccccaatacaagcaagacagtgtcataactgacagaatc
aactacgacctactccgcaagtgtgacagcatcacaaaaggagaggagcgatgcccagaa
cttattggtgacccagtcaatcggggcaaatga
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