Oreochromis niloticus (Nile tilapia): 100534581
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Entry
100534581 CDS
T06104
Symbol
hsd17b8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
onl
Oreochromis niloticus (Nile tilapia)
Pathway
onl00061
Fatty acid biosynthesis
onl00140
Steroid hormone biosynthesis
onl01100
Metabolic pathways
onl01212
Fatty acid metabolism
Module
onl_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
onl00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100534581 (hsd17b8)
00140 Steroid hormone biosynthesis
100534581 (hsd17b8)
Enzymes [BR:
onl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
100534581 (hsd17b8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
100534581 (hsd17b8)
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GFIT
Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
Polysacc_synt_2
3HCDH_N
3Beta_HSD
RmlD_sub_bind
GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID:
100534581
NCBI-ProteinID:
NP_001266465
Ensembl:
ENSONIG00000020036
UniProt:
Q49RA9
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Position
LG22:complement(8311962..8315951)
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AA seq
256 aa
AA seq
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MAVATRLISRLTLVTGGGSGIGRAVCQRFASEGASVVVADLSEESANETLGSLQSDLRGQ
AHTAAVVDVSSKESIKKLVTSVQTRYFQPPSVCVNAAGITQDDFLLNMEEEQLDKVIQTN
LKGSFLITQAVAQALVACGAPKGSIITVGSIVGKVGNTGQANYAASKAGVEGLTRTAAKE
LSRFGIRCNCVLPGFITTPMTDKVPEKVISKIESSVPLGRMGEPAEVADVCAFLASDDSQ
YITGASIEVTGGLFMG
NT seq
771 nt
NT seq
+upstream
nt +downstream
nt
atggcggttgccacaaggctcatctcaaggttgacgctggtcaccggtggaggcagtggg
atcgggcgggcagtgtgccagcgttttgcctctgagggcgcctccgtggtggtcgccgac
ctcagcgaggagtcggccaatgagacgctggggagtctgcagagcgacctcagagggcag
gcccacacggcggctgtagtggacgtgtcgtctaaagagagcatcaagaagctggtaacg
agcgtgcagactcggtacttccagcctccctcggtgtgcgtgaatgcagccggcatcact
caggacgacttcctgctcaacatggaggaggagcagcttgataaagtcatccagaccaac
ctgaagggttcattcttgatcactcaggcggtcgctcaggctctggtggcctgtggagcg
cccaaaggatccatcattactgtgggcagcatcgtgggaaaggtaggaaacaccggtcag
gctaactacgctgcctctaaagctggagtcgagggtttaacaaggaccgccgccaaagag
ctcagcaggtttgggattcgctgtaactgcgtgctgccggggttcattacgactccaatg
acagataaagtgccagagaaggttattagcaagatcgagtcctcggtgcctctgggaagg
atgggcgagccggcagaggtcgctgatgtctgcgccttcctcgcctcggacgactctcag
tacatcaccggagccagcatcgaagtgacaggcggacttttcatgggttaa
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