Orcinus orca (killer whale): 101272632
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Entry
101272632 CDS
T05247
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00061
Fatty acid biosynthesis
oor00620
Pyruvate metabolism
oor00640
Propanoate metabolism
oor01100
Metabolic pathways
oor04152
AMPK signaling pathway
oor04910
Insulin signaling pathway
oor04920
Adipocytokine signaling pathway
oor04922
Glucagon signaling pathway
oor04931
Insulin resistance
oor04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
101272632 (ACACB)
00640 Propanoate metabolism
101272632 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101272632 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
101272632 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
101272632 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101272632 (ACACB)
04922 Glucagon signaling pathway
101272632 (ACACB)
04920 Adipocytokine signaling pathway
101272632 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101272632 (ACACB)
04931 Insulin resistance
101272632 (ACACB)
Enzymes [BR:
oor01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
101272632 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
101272632 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
101272632 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
101272632
NCBI-ProteinID:
XP_004281429
LinkDB
All DBs
Position
15:71802789..71941884
Genome browser
AA seq
2456 aa
AA seq
DB search
MILLLFLSYLILSCLIFSWLKSWGKMTDSKEVTKSKLKVSFIASQEPLPASDSSREPLQE
NCSSSSLPETPDQAEPASHKGPKDTCQQRNSQPPLLQNPQGNPLSSDDPFPTRQANRTEN
EGLETPNTSGPSVLARPQGQRARTLSKEDRKRAHIKKQLMTNFILGSFDDNSSDEDSGTG
LFRESSRKGSRASLGTLSLEAAQTAGETETPVPTIRPSMSGLHLARRGREQKKPDLHRDF
TVASPAEFVVRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVLVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPE
LLHKHEIAFLGPPSEAMWAVGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSLQQGQRI
SVPEYIYNDGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKVETAEDFPILFRQVQS
EIPGSPVFLMKLAQHAHHLEVQLLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPA
VFEIMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPIARGHVIAARITSENPDEGF
KPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLTNLLETESFQNNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNV
ADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNG
CHIEIDAHRLNDGGLLLSYSGSSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRAPST
GKLIQYMVEDGDHIEAGGSYAEIEVMKMITTLNVQESGRVKYVKRPGAVLEAGCVVARLD
LDDPSKVHPAEPFTGELPSQPTLPILGEKLHQVFRSVLENLRNIMKGYCLPEPIFSIKLK
DWVQKLLMTLRHPTLPLLDLQEIMTSVSGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRKADREVFFMNTQSIVQLVQKYRSGTRGYMKAVVLDLLRRYLLVEH
HFQQAHYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDEL
TSILSELTQLSKSKHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELTSLQHRQLRDGTCVVE
FQFMLPSSHPNRMAVPISITNPELLRHSTELFMDSGFSPKSQRMGAMVAFQRFEDFTRNF
DEVISCFANVPKDVPLFSKARTSLYSEDDRKSLREEPIHILNVAIQYADYLEDEQLVPVF
RTFVQSKKNILVEYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRLRNFDITAMPCANHKMHLYLGAARVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTTDRAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGN
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWGSPDKYPKDI
LTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTLEYPEGRDVILISNDITFRIGSF
GLGEDLLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVDREDPHKGIKYL
YLTPQDYTTVSSLNSIHCKHIEEEGESRYVITDIIGKEDGLGVENLRGSGMIAGETSLDY
DEIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGAMALNKVLGREVYTSNNQLGG
VQIMHYNGVSHVTVPDDFEGVCTILEWLSYMPKDNRSPVPIITPTDPIDREIEFQPSRSP
YDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETR
TVELAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIQDFNREKLPLMIFANWRGFSG
GMKDMYDQVLKFGAYIVDGLRKYKQPVLIYIPPCAELRGGSWAVMDTSINPLCIEIYADR
ESRASVLEPEGTVEIKYRKKDLVKTMRRIDPIYQKLVEQLGMSELSDKHRKELEGQLKAR
EDLLLPIYHQVAVQFADLHDKPSRMLEKGTISDILDWKTARTFLYWRLRRLLLEDQVKQE
VLQACSDLNHVHVQSMLRRWFMEMEGAVKAYLWDNNQTAVQWLEQHWQAGEGLRSTIREN
IEYLKRDSVLKTIRGLVQENPEVAVDSVVYICQHVSPAERAQIIHLLSTMDSPAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgatcctgcttctttttctatcttatctgattttgtcctgcctgatcttttcctggtta
aaaagctgggggaaaatgacggactccaaggaagtcaccaagagtaaattgaaggtgagc
ttcatcgcaagtcaggagcctcttccagcctcagacagctccagggagccactgcaggaa
aattgcagcagcagctctctgccagagacccctgaccaggctgagccagcctcccacaaa
ggtcccaaagacacctgccagcaaagaaactcccagccacccctgctgcagaatccccaa
ggaaaccccctttcctccgatgaccccttcccaacacgccaagctaacaggacagagaac
gaaggcctggagaccccaaataccagtggcccgtccgtgctagccagaccccagggccag
cgagccagaactctctccaaagaagacaggaagcgggcgcacatcaagaagcaactgatg
accaacttcatcctgggctcttttgacgacaactcttccgatgaggactctggcactggc
ttgttcagagaatcttcccggaagggcagccgcgccagcctggggaccctgtccctggag
gctgctcagaccgcaggcgagactgagacccctgtccccactataaggcccagcatgtcc
ggactccacctggcgagaagaggccgagaacagaagaagccggacctgcacagagacttt
actgtggcttcccctgccgagttcgtcgtgcgctttgggggggatcgggtcatcgagaag
gtgctcatcgccaacaatggtatcgccgccgtgaaatgcatgcgctccatccgcaggtgg
gcctatgagatgttccgaaatgagcgggccatccggtttgtagtcttggtaacccccgag
gacctcaaagccaacgcagagtatatcaagatggcagatcagtacgtccccgtcccagga
gggcccaacaacaacaattatgccaacgtggagctgattgtggacattgccaagaggatc
cccgtgcaggcggtgtgggctggctggggccatgcttctgaaaaccccaaacttccggag
ctcctgcacaagcacgagattgctttcttaggccctcccagcgaggccatgtgggcagtg
ggagacaagatcgcctccaccatcgtggcccagacgctgcagatcccaacgctgccctgg
agcggaagcggtctgacggtggagtggacagaagatagtctgcagcaggggcaaaggatc
agcgtcccagagtacatttacaacgatggttgcgtgaaagatgtcgacgagggcttggag
gcagcagaaaaaattggttttcccttgatgatcaaagcttctgaaggcggtggagggaaa
ggcatccggaaggtggagactgctgaggacttcccaatacttttcagacaagtgcagagc
gagatccccggctccccagtctttctcatgaagctggcccagcacgcccatcacctggag
gtccagctcctcgctgaccagtatgggaacgccgtgtccttgtttgggcgcgactgttcc
atccagcggaggcatcagaagatcatagaggaggcgccggccaccattgccacgccagcc
gtgttcgagatcatggagcagtgtgccgtgcgcctggccaagaccgtgggctacgtgagt
gcggggaccgttgaatacctctacagccaggatggcagcttccacttcttggagctgaat
ccccgcctgcaggtggaacatccctgcacggaaatgatcgccgatgtcaacctgccggcc
gcccagctacagatcgccatgggcgtgcctctgcaccggctgaaggatatccggcttctc
tatggagagtccccatggggggtgacgcccatttcttttgagaccccttccaaccctccc
atcgcccgaggccacgtcattgcggccagaatcaccagcgaaaacccagatgaggggttt
aagccgagctctggaacggtccaggagttgaatttccgcagcagcaagaacgtgtggggt
tatttcagcgtggctgccactggaggcttacatgaatttgccgattcccagtttgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaag
gaactctccatccggggcgacttcaggactaccgtggaatatctcaccaacctcctggag
accgagagcttccagaacaacgacattgacaccagctggttggataatctcatcgccgag
aaagtgcaggccgagaagccggatatcatgctcggggtggtgtgcggagccttgaacgtg
gccgactcgatgttcaggacctgcatgacggatttcttacactcgctggagaggggccag
gtcctccccgcagactctctgctgaacattgtggatgtagaattgatctacggaggcgtt
aaatacatcctcaaggtggcccggcagtctccaaccatgttcgtcctcatcatgaacggc
tgtcacatcgagattgacgcccaccggctgaacgacggggggctgctgctgtcctacagt
ggcagcagctacaccacgtacctgaaggaggaggtcgacagttaccgaatcaccatcggc
aacaagacgtgtgtgtttgagaaggagaatgatcccacggtcctgagagccccttcgacg
gggaagctgatacagtacatggtggaggacggggaccacatcgaggctgggggcagctat
gctgagatagaggtgatgaagatgatcacgaccctgaatgtgcaggaaagtggccgggtg
aagtacgtcaagcgcccaggggctgtgttggaagcaggctgtgtggtggccaggctggac
ctcgatgacccttctaaagtgcacccggctgagccattcacgggagagctcccctcccaa
ccaacgctgcccatcctcggagagaaactgcaccaggtttttcgcagcgtcctggaaaat
ctgaggaacatcatgaagggctactgtctgccggagcctatttttagcatcaagctgaag
gactgggtgcagaagctcctgatgaccctgcggcacccaacgctgccactgctggatctg
caggagatcatgaccagcgtgtcgggccgcatccccgcccccgtggagaaggctgtccgc
agggtgatggcccagtacgccagcaacatcacctcggtgctgtgccagttccccagccag
cagatagccaccatcctggactgccatgcggccaccctgcagcggaaggccgatcgggag
gtcttcttcatgaacacccagagcattgtgcagctggtccagaaataccgcagtgggacc
cggggctacatgaaggcggtggtgttggatctcctgcgaagatatttactggttgagcac
catttccaacaagcccactacgacaagtgtgtgataaacctcagggagcagctgaaacca
gacatgtcccaggtgttggactgcatcttctcccatgcgcaggtggccaagaagaaccag
ctggtgatcatgttgatcgatgagctctgtggcccagacccttccctgtcagatgagctg
acctccatcctcagcgagctcactcagctgagcaaaagcaagcactgcaaagtggccctc
agagccaggcaggtcctgattgcctcccacctcccctcctatgagctgaggcacaaccag
gtggagtccattttcctgtctgccatcgacatgtatggccaccagttctgcccggaaaac
ctcaagaaattaatactctcagaaacgaccatatttgacgtcctgcccactttcttctat
catgctaacaaagtcgtctgcatggcatccttggaggtttatgtgcggaggggctacatc
gcctacgagttaaccagcctgcagcaccggcagctccgggacggcacctgcgtggtggaa
ttccagttcatgctgccctcctcccacccaaaccggatggccgtacccatcagcatcacc
aaccctgaactgctgaggcacagcacggagctcttcatggacagtggcttctcccccaag
tcccagcggatgggggccatggttgccttccagagattcgaggatttcaccaggaacttt
gatgaggtcatttcctgctttgccaacgtgcctaaggacgttcctctcttcagcaaggcc
cgtacttccctgtactccgaggatgacaggaagagcctccgagaagagccgatccacatc
ctgaacgtggccatccagtacgcagactacctggaggacgagcagctggtgcctgttttc
cggacattcgttcagtccaagaaaaacatccttgtggagtatggactccggagaattacg
ttcctgattgcccaagagaaagaatttcccaagtttttcacattcagagcaagagacgag
tttgcagaagatcgcatttaccgtcacttggagccggccctggccttccagctggagctc
agccggttgcgtaactttgacataactgccatgccctgcgccaaccacaagatgcatttg
tacctgggcgctgccagagtgaaagagggcgcagaggtcacggaccacaggttcttcatc
cgcgtcatcatcaggcattcggacctgatcaccaaggaagcctccttcgagtacctgcag
aacgaaggcgagcggctgcttctggaggccatggacgagctggaggtggcgttcaacaac
accagcgtgcgcaccgactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatg
gacccctctaagattgaggagtcagtgcggtccatggtgatgcgctacggcagccggttg
tggaaactccgcgtgctccaggctgaggtcaagatcaacatccgccagaccaccaccgac
cgcgccgttcccatccgcctgttcatcaccaacgagtcaggctactacctggacatcagc
ctctacaaagaagtgaccgaccccagatctggaaacatcatgtttcactccttcggcaac
aaacaagggccccagcacgggatgctgatcaatactccgtacgtcaccaaggatctgctc
caggctaagcgattccaggcccagtccctgggtaccacctatgtgtatgacttcccggaa
atgttcaggcaggctctttttaaaatgtggggttccccggacaagtaccccaaagacatc
ctgacatacaccgaactagtgctggacccgcagggccagctggtggagatgaaccgactt
cctggaggaaatgaggtgggcatggtggccttcaaaatgaggtttaagacccttgagtac
ccagaagggcgcgacgttatcctcatcagcaatgacatcaccttccggataggatccttt
ggccttggagaagaccttctgtacctgcgggcatccgagatggcccgggcagagggcatc
cccaaaatctacctcgctgccaacagtggggcccgtatcggccttgcggaggagatcaaa
cacatgttccaggtggcttgggtggaccgggaagacccccacaagggaattaaatacctg
tacctgactccccaagactacaccacagtcagctccctgaactccatccattgtaaacac
atcgaggaagaaggagaatccaggtatgtcatcacggatatcattgggaaggaggatggc
ctgggcgtagagaacctgaggggctcaggcatgattgctggggagacctccctggattat
gatgagattgtcaccatcagcttggtgacctgccgagcccttgggatcggtgcctacctg
gtgaggctgggccagcgagtgatccaggtggagaattcccacatcatcctgacaggggca
atggctctcaacaaggtcctgggcagagaggtttacacatccaacaaccagctgggcggc
gtgcagatcatgcattacaatggtgtctcccatgtcaccgtgccggatgacttcgagggt
gtttgtaccatcctggagtggctgtcctatatgccaaaggataatcgcagccctgtccca
atcatcacacccactgaccccattgacagagagattgaattccaaccatctcgctcaccc
tatgacccccggtggttgcttgcaggaaggcctcacccaaccctgaagggatcctggcag
agtggattcttcgaccagggcagtttcaaggaaatcatggtgccctgggcccagaccgtg
gtcacgggacgagcaaggctgggggggatccccgtcggagtgatcgctgcagagacacgg
acagtggagttggctgtgcccgcggaccctgccaacctggattccgaggccaagataatc
cagcaggccggccaggtgtggttcccagactcggcctacaagacagcgcaggccatccag
gatttcaaccgggagaagttgcccctcatgatctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccaggtgctgaagtttggagcctacattgtggatggcctc
cggaagtacaaacagcctgtcctgatctacatcccgccctgcgcggagctgcggggaggc
tcctgggcggtcatggacacctccatcaacccactgtgcatagaaatatacgcggacaga
gagagcagagcgagtgttctggagccagagggaacagtggagattaagtaccggaagaaa
gatctggtaaagaccatgagaagaatcgacccaatttaccagaagcttgtggaacagcta
ggaatgtctgagctctccgacaagcaccgcaaggagctggagggccagctgaaggcccgg
gaggacctgctgctgcccatctaccaccaggtggcggtgcagttcgccgacctccacgac
aagcccagcaggatgttggagaagggtaccatctctgacatcctggattggaagaccgcc
cgcaccttcctgtactggcgtctgcgtcgcctgctgctggaggaccaggtcaagcaggag
gtcctgcaggcctgcagcgacctcaaccacgtgcacgtccagtccatgctgcgccgctgg
ttcatggagatggagggggccgtcaaggcctacctgtgggacaacaaccagacggcagtg
cagtggctggagcagcactggcaggcgggggaggggctgcgctccaccatccgcgagaac
atagagtacttgaagcgagactctgtcctcaagaccatccgaggcctggttcaagaaaac
cccgaggtggccgtggactccgtggtgtacatatgtcagcacgtcagcccggccgagcgg
gcccagatcattcacctcctgtccaccatggacagcccggcctccacctga
DBGET
integrated database retrieval system
