KEGG   Orcinus orca (killer whale): 101276033
Entry
101276033         CDS       T05247                                 
Symbol
DNMT1
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 1 isoform X1
  KO
K00558  DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00270  Cysteine and methionine metabolism
oor01100  Metabolic pathways
oor05206  MicroRNAs in cancer
Module
oor_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    101276033 (DNMT1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    101276033 (DNMT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:oor03000]
    101276033 (DNMT1)
   03032 DNA replication proteins [BR:oor03032]
    101276033 (DNMT1)
   03036 Chromosome and associated proteins [BR:oor03036]
    101276033 (DNMT1)
  09183 Protein families: signaling and cellular processes
   02048 Prokaryotic defense system [BR:oor02048]
    101276033 (DNMT1)
Enzymes [BR:oor01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     101276033 (DNMT1)
Transcription factors [BR:oor03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    101276033 (DNMT1)
DNA replication proteins [BR:oor03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    101276033 (DNMT1)
Chromosome and associated proteins [BR:oor03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    101276033 (DNMT1)
Prokaryotic defense system [BR:oor02048]
 Restriction and modification system (R-M system)
  Type II R-M system
   DNA methyltransferases
    101276033 (DNMT1)
SSDB
Motif
Pfam: BAH DNA_methylase DNMT1-RFD DMAP_binding zf-CXXC HTH_12
Other DBs
NCBI-GeneID: 101276033
NCBI-ProteinID: XP_012391296
LinkDB
Position
3:complement(6839852..6882282)
AA seq 1621 aa
MPARTAPARVPALASRAFSLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
LCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGAHAFSREVNGCLENGSQTSGEEHRV
EIAEKKKSPKPVSKLCMPRRSKSDAETKSAEVSSSPRITRQTTRQTTITSHFTRGPAKRK
PEEDAEKAKSDDSVDEEEKDQEEKRRRVTSRERVAGLLPAEEPGRVRPGTHVEEEERDDK
VKPGHLQEEKRLRSQTKELTPKQKSKEEPDRDARPGGAQAEMNEGEDKDEKRHRSQPKDL
ASKRRPEEKEPEGVKPQVSDEKDEDEKEEKRRRTTCKEPTEKKMARTKMAVVSSKTDPLK
CIECGQYLDDPELRYEQHLPDAVEEIQLLTNERLSIFDANESGFESYEDFPQHKLTCFSV
YCKRGHLCPIDTGLIEKDVELLFSGSAKPIYEDDPSPEGGVNGKNLGPINEWWIAGFDGG
EKALLGFSTSFAEYILMDPSPEYAPLFSVMQEKIYISKIVVEFLQNNPDSTYEDLINKIE
TTVPPSMLNLNRFTEDSLLRHAQFVVEQVESYDRAGDSDEQPIFLTPCMRDLIKLAGVTL
GKRRAERRQTIRHPAKEKDRGPTKATTTKLVYQIFDTFFAEQIEKDDKEDKENAFKRRRC
GVCEICQQPECGKCKACKDMVKFGGSGRSKQACQKRRCPNMAMKEADDDEEVDDNIPEMP
SPKKMHQGKKKKQNKDRIFWVGEAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKP
LYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVQ
VVYKAPSENWALEGGVDPEALMSEGDGKTYFYQLWYDQDYARFESPPKTQPMEDNKYKFC
ASCARLAEMRQKEIPRVMEQLEDLDGRVLYSLATKNGIQYRVGDGVYLPPEAFTFNIKLS
SPVKRPRKEPVDEALYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCSKKSNGRPNETD
IKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECLQ
DFSAGGPDRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKSRTKSQSSEPSELETE
IKLPKLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNSGSTVFTEDCNV
LLKLVMAGEVTNSRGQKLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLS
YCDYYRPRYFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRA
IILAAAPGEQLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSD
LPEIRNGASAQEISYNGEPQSWFQRQLRGSQYQPILRDHICKDMSALVAARMRHIPLAPG
SDWRDLPNIEVRLSDGTLARKLRYNYHDKKNGCSSAGALRGVCSCVEGKACDPAARQFNT
LIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECA
RSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKRCMMVRARESTSVKIKEETAK
D
NT seq 4866 nt   +upstreamnt  +downstreamnt
atgcctgcacgtaccgccccagcccgggtgcccgcgctggcctcccgggccttctcactg
cccgacgatgtccgcaggcggctcaaagatttggaaagagatagtttaacagaaaaggaa
tgcgtgaaggagaaattgaatctcttgcatgaatttctgcagacagaaataaagaatcaa
ttatgtgacttggaaaccaaattacataaagaagaattatcagaggagggctacctggct
aaagtcaaatcccttttaaataaagatttgtccttggagaacggagctcatgctttcagt
cgggaagtgaatggatgtctagaaaacgggagccagacaagtggtgaggagcacagagtg
gaaatagcagagaaaaagaagtcccccaaacctgtttccaaactttgcatgcccaggaga
agcaagtccgatgcagaaacaaaatcagctgaagtctcatctagccccaggattacaagg
caaactaccaggcagaccaccatcacatctcatttcacaaggggccctgccaaacggaaa
cctgaggaagacgctgaaaaagcaaaatcagatgattctgtcgatgaagaagaaaaagac
caggaggaaaagagacgtagagttacatccagagaacgagttgctggactgctccctgca
gaagaaccgggaagagtaagaccaggaacacacgtggaagaagaagaaagagatgataaa
gtaaagcctggtcacctccaggaagaaaagagactcagaagtcaaaccaaagaactaaca
cctaaacagaaatctaaggaggagccagacagagatgcaaggcccggaggagctcaggct
gaaatgaatgaaggagaagacaaagatgaaaagaggcacagaagtcaacccaaagatcta
gctagcaaacggagaccagaagaaaaagaacctgaaggagtaaaaccacaagtttctgat
gagaaagatgaggatgaaaaggaggagaagagacgcagaactacatgcaaagaaccaact
gagaagaaaatggctcgaaccaaaatggcagtagtgtcctccaagaccgatcctctgaag
tgcattgagtgcggacagtacctggatgaccccgagctaagatatgaacagcatctccct
gatgcagtggaagagatacagttgttgacaaatgagagactgtccatctttgatgccaat
gaatctggctttgagagttacgaggattttccccaacacaaactgacctgcttcagcgtg
tactgtaaacgaggtcacctgtgcccgatcgacaccggcctcattgagaaggatgtcgag
ctcctcttttctggttcagcaaagccaatatatgaggatgacccgtctcccgaaggtggt
gttaatggcaaaaatcttggtccaataaatgaatggtggattgctggctttgatggaggt
gaaaaggctctccttggctttagcacctcatttgccgaatacattttgatggatcccagc
ccagagtatgcacctctgttcagtgtgatgcaggagaagatctacataagcaagatagta
gttgagttcctgcagaacaaccctgactcaacatacgaagacctgatcaataagatcgag
accactgttcctccttctatgctcaacctgaatcgattcacagaggattctctccttcga
cacgcccagtttgtggtggaacaagtagagagttatgatcgggctggggacagtgacgag
cagcccatcttcctgaccccctgcatgagagacctgatcaagttggccggggtcaccttg
gggaaaaggcgagctgaaaggcggcagaccatccggcatcctgccaaggagaaggacaga
ggccccaccaaagccaccactacgaagctggtctaccagatctttgacactttctttgcg
gagcaaattgaaaaggatgacaaagaagacaaggagaacgcctttaaacgccggcggtgt
ggcgtctgtgagatttgtcaacagcctgagtgtggaaagtgtaaagcctgtaaggatatg
gttaaatttggtggcagcggaaggagcaaacaggcttgccaaaagaggaggtgtcccaac
atggccatgaaggaggcagatgatgatgaagaagtggatgacaatattccagagatgcca
tcacccaaaaagatgcatcaggggaagaaaaagaagcagaacaaggatcggatcttttgg
gttggagaagctgtcaagaccgatgggaagaagagttactataagaaggtatgcatcgac
tcggaaaccctggaagtgggggactgtgtttctgttattccagatgattcttcaaaacca
ctgtatttagcaagggtcacggcgctgtgggaggacagcagcaacgggcagatgtttcat
gcccactggttctgtgctgggacggacacagtcctcggggccacgtcggaccccctggag
ctgttcctggtagacgaatgtgaggacatgcagctttcatacattcacagcaaagtgcag
gtcgtctataaagccccgtcggaaaactgggccttggagggaggcgtggaccctgaggcc
ctgatgtcggagggtgacggaaagacctatttctaccagctttggtatgaccaagactac
gcaagatttgagtcccctccaaaaactcagccaatggaggacaacaagtacaagttctgt
gcaagctgtgcacgtctggctgaaatgaggcagaaggaaattcccagggtcatggagcag
ctcgaggacctggatggccgggtcctctacagcttagccaccaagaacggcatccagtat
cgagtgggcgatggcgtgtacctcccccccgaggccttcaccttcaacattaagctgtcc
agtcctgtgaaacgcccacggaaggagcctgtggatgaagctctgtatccagaacactac
cggaaatactctgactacatcaaaggcagcaacctagatgcccctgagccgtaccgtatt
ggccgcatcaaagagatcttctgcagcaagaagagcaacggcaggcccaacgagacggat
atcaagatcagagtcaacaagttttacaggccggagaacacgcacaagtccaccccggcg
agttaccacgcagacatcaacctgctttattggagcgacgaggaggctgtggtggacttc
aaggccgtgcagggccgctgcaccgtggagtacggggaggacctgcctgagtgcctccag
gacttctccgctggtggccccgaccgcttctacttccttgaggcctataatgccaagagc
aaaagctttgaagatcctccaaaccatgcccgtagccctggaaataaagggaaagggaag
ggaaaagggaaaagcaggacaaagtcgcaaagctctgagccgagcgagctggagacggaa
atcaagctgccgaagctgcggaccctggatgtgttttctggctgtgggggtttgtcggaa
gggttccaccaagcaggcatctcggaaacgctgtgggccatcgagatgtgggaccccgcg
gcccaggcgttccggctgaacaattccgggtccacggtgttcacagaggactgcaacgtc
ctgctgaaactggtcatggccggggaggtgaccaactcccgcggccagaagctgccgcag
aagggagacgtggagatgctgtgtggcgggcctccttgccaaggctttagcggcatgaac
cgcttcaactctcgaacatactctaagttcaagaactccctggtggtctccttcctcagc
tactgcgactactaccggcccaggtacttcctcctggagaatgtcaggaacttcgtctcc
ttcaagcgctccatggtcctgaagctcacgctccgctgcctggtccgcatgggctaccag
tgcaccttcggcgtgttgcaggctggtcagtacggcgtggcccagacgcggaggcgggcc
atcatcctggccgcggcccccggagagcagctccctctgttcccggagccgctgcacgtg
ttcgcgccccgggcctgccagctgagtgtcgtagtcgacgacaagaagtttgtcagcaac
atcaccaggttgagctcgggtccgttccgaaccatcaccgtgcgggacacgatgtccgac
cttcccgagattcggaacggagcttcggcgcaggagatctcgtacaacggggagcctcag
tcctggttccagaggcagctccggggctcgcagtaccagcccatcctcagggaccacatc
tgtaaggacatgagcgcgttggtggctgctcgcatgcggcacatccctctagccccgggc
tcagactggcgtgacctgccaaacatcgaggtgcggctctctgatggcaccttggccagg
aagctgcggtacaactaccacgacaagaagaacggctgcagcagcgccggggctctccgc
ggggtctgctcctgcgtggaaggcaaagcctgtgaccctgcggccagacagttcaacacc
ctcattccctggtgcctgccccacaccgggaacaggcacaaccactgggccggcctctat
ggacggctcgagtgggacggcttcttcagcacgaccgtcaccaaccccgagcccatgggc
aagcagggccgcgtgctccacccagagcagcaccgcgtcgtgagtgtgcgggagtgcgcc
cgctctcagggcttccccgacacctaccggctgttcggcaacatcctggacaagcaccgg
caggtgggtaacgctgtgccaccgccactggccaaagccatcggcttggagatcaagcgc
tgtatgatggtcagagcgcgagagagcacctcagttaaaatcaaggaggagactgctaag
gactag

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