Orcinus orca (killer whale): 101276350 Help Entry 101276350         CDS       T05247                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism oor  Orcinus orca (killer whale) Pathway oor01521   EGFR tyrosine kinase inhibitor resistance oor04010   MAPK signaling pathway oor04012   ErbB signaling pathway oor04014   Ras signaling pathway oor04015   Rap1 signaling pathway oor04020   Calcium signaling pathway oor04066   HIF-1 signaling pathway oor04070   Phosphatidylinositol signaling system oor04071   Sphingolipid signaling pathway oor04072   Phospholipase D signaling pathway oor04150   mTOR signaling pathway oor04151   PI3K-Akt signaling pathway oor04261   Adrenergic signaling in cardiomyocytes oor04270   Vascular smooth muscle contraction oor04310   Wnt signaling pathway oor04360   Axon guidance oor04370   VEGF signaling pathway oor04510   Focal adhesion oor04540   Gap junction oor04613   Neutrophil extracellular trap formation oor04650   Natural killer cell mediated cytotoxicity oor04664   Fc epsilon RI signaling pathway oor04666   Fc gamma R-mediated phagocytosis oor04670   Leukocyte transendothelial migration oor04713   Circadian entrainment oor04720   Long-term potentiation oor04723   Retrograde endocannabinoid signaling oor04724   Glutamatergic synapse oor04725   Cholinergic synapse oor04726   Serotonergic synapse oor04727   GABAergic synapse oor04728   Dopaminergic synapse oor04730   Long-term depression oor04750   Inflammatory mediator regulation of TRP channels oor04911   Insulin secretion oor04912   GnRH signaling pathway oor04916   Melanogenesis oor04918   Thyroid hormone synthesis oor04919   Thyroid hormone signaling pathway oor04921   Oxytocin signaling pathway oor04925   Aldosterone synthesis and secretion oor04926   Relaxin signaling pathway oor04928   Parathyroid hormone synthesis, secretion and action oor04929   GnRH secretion oor04933   AGE-RAGE signaling pathway in diabetic complications oor04935   Growth hormone synthesis, secretion and action oor04960   Aldosterone-regulated sodium reabsorption oor04961   Endocrine and other factor-regulated calcium reabsorption oor04970   Salivary secretion oor04971   Gastric acid secretion oor04972   Pancreatic secretion oor05017   Spinocerebellar ataxia oor05022   Pathways of neurodegeneration - multiple diseases oor05031   Amphetamine addiction oor05032   Morphine addiction oor05143   African trypanosomiasis oor05146   Amoebiasis oor05161   Hepatitis B oor05163   Human cytomegalovirus infection oor05164   Influenza A oor05170   Human immunodeficiency virus 1 infection oor05171   Coronavirus disease - COVID-19 oor05200   Pathways in cancer oor05205   Proteoglycans in cancer oor05206   MicroRNAs in cancer oor05207   Chemical carcinogenesis - receptor activation oor05214   Glioma oor05223   Non-small cell lung cancer oor05225   Hepatocellular carcinoma oor05231   Choline metabolism in cancer oor05415   Diabetic cardiomyopathy oor05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oor00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101276350 (PRKCA)    04012 ErbB signaling pathway     101276350 (PRKCA)    04014 Ras signaling pathway     101276350 (PRKCA)    04015 Rap1 signaling pathway     101276350 (PRKCA)    04310 Wnt signaling pathway     101276350 (PRKCA)    04370 VEGF signaling pathway     101276350 (PRKCA)    04066 HIF-1 signaling pathway     101276350 (PRKCA)    04020 Calcium signaling pathway     101276350 (PRKCA)    04070 Phosphatidylinositol signaling system     101276350 (PRKCA)    04072 Phospholipase D signaling pathway     101276350 (PRKCA)    04071 Sphingolipid signaling pathway     101276350 (PRKCA)    04151 PI3K-Akt signaling pathway     101276350 (PRKCA)    04150 mTOR signaling pathway     101276350 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101276350 (PRKCA)    04540 Gap junction     101276350 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     101276350 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     101276350 (PRKCA)    04664 Fc epsilon RI signaling pathway     101276350 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     101276350 (PRKCA)    04670 Leukocyte transendothelial migration     101276350 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     101276350 (PRKCA)    04929 GnRH secretion     101276350 (PRKCA)    04912 GnRH signaling pathway     101276350 (PRKCA)    04921 Oxytocin signaling pathway     101276350 (PRKCA)    04926 Relaxin signaling pathway     101276350 (PRKCA)    04935 Growth hormone synthesis, secretion and action     101276350 (PRKCA)    04918 Thyroid hormone synthesis     101276350 (PRKCA)    04919 Thyroid hormone signaling pathway     101276350 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     101276350 (PRKCA)    04916 Melanogenesis     101276350 (PRKCA)    04925 Aldosterone synthesis and secretion     101276350 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101276350 (PRKCA)    04270 Vascular smooth muscle contraction     101276350 (PRKCA)   09154 Digestive system    04970 Salivary secretion     101276350 (PRKCA)    04971 Gastric acid secretion     101276350 (PRKCA)    04972 Pancreatic secretion     101276350 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101276350 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     101276350 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     101276350 (PRKCA)    04727 GABAergic synapse     101276350 (PRKCA)    04725 Cholinergic synapse     101276350 (PRKCA)    04728 Dopaminergic synapse     101276350 (PRKCA)    04726 Serotonergic synapse     101276350 (PRKCA)    04720 Long-term potentiation     101276350 (PRKCA)    04730 Long-term depression     101276350 (PRKCA)    04723 Retrograde endocannabinoid signaling     101276350 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101276350 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     101276350 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     101276350 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101276350 (PRKCA)    05206 MicroRNAs in cancer     101276350 (PRKCA)    05205 Proteoglycans in cancer     101276350 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     101276350 (PRKCA)    05231 Choline metabolism in cancer     101276350 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101276350 (PRKCA)    05214 Glioma     101276350 (PRKCA)    05223 Non-small cell lung cancer     101276350 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101276350 (PRKCA)    05161 Hepatitis B     101276350 (PRKCA)    05171 Coronavirus disease - COVID-19     101276350 (PRKCA)    05164 Influenza A     101276350 (PRKCA)    05163 Human cytomegalovirus infection     101276350 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     101276350 (PRKCA)    05143 African trypanosomiasis     101276350 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     101276350 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     101276350 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     101276350 (PRKCA)    05032 Morphine addiction     101276350 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101276350 (PRKCA)    05415 Diabetic cardiomyopathy     101276350 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     101276350 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101276350 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oor01001]     101276350 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oor04131]     101276350 (PRKCA) Enzymes [BR:oor01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      101276350 (PRKCA) Protein kinases [BR:oor01001]  Serine/threonine kinases: AGC group   PKC family [OT]    101276350 (PRKCA) Membrane trafficking [BR:oor04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     101276350 (PRKCA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2 Motif Other DBs NCBI-GeneID:  101276350 NCBI-ProteinID:  XP_004275451 LinkDB All DBs Position 19:complement(22010438..22378774) Genome browser AA seq 670 aa AA seqDB search MADVFPANDSAAPQDVANRFARKGALRQKNVHEVKDHRFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTEEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE LRQKFEKAKLGPAGYKGISPDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE ELYAIKILKKDVVIQDDDVECTLVEKRVLALPDKPPFLTQLHSCFQTVDRLYFVMEYVNG GDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADF GMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED EDELFQSIMEHNVSYPKSLSREAVSICKGLMTKHPGKRLGCGPEGERDVREHTFFRRIDW EKLENREVQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQ FVHPILQSTV NT seq 2013 nt NT seq  +upstreamnt  +downstreamnt atggctgacgtcttcccggccaacgactcggcggcgcctcaggacgtggccaaccgcttc gcccgcaaaggggcgctaagacagaagaacgtgcacgaggtgaaggaccaccgcttcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgactttatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgttactttctcttgtccgggtgcagataaaggacccgacactgatgaccccaggagc aagcacaaattcaagatccacacctatggaagccccaccttctgcgaccactgtgggtca ctgctgtacggactcatccaccaggggatgaagtgtgacacctgtgatatgaacgtgcac aagcagtgcgtgataaacgtccccagcctctgcgggatggaccacacggagaagaggggc cggatctacctgaaggccgaggtcaccgaggaaaagctccacgtcacagtacgagatgca aaaaatctcatccctatggatccaaatgggctttcagatccttatgtgaagctgaagctt attcctgaccccaagaacgaaagcaaacaaaaaaccaaaaccatccgttccacactgaac ccccagtggaatgagtcctttacgttcaaattaaaaccttcggataaagaccgacgactg tccgtagagatctgggactgggatcgaacaaccaggaacgacttcatggggtccctttcc ttcggagtctcggagctgatgaagatgccggccagtggatggtacaagctgctgaaccaa gaggagggtgagtactacaacgtgcccattccagaaggcgacgaggaaggcaacgcggag ctgaggcagaagttcgagaaagccaagctcggccctgctggctacaaaggcattagtcct gacaggagacagccttccaacaacctcgacagagtgaaactcaccgacttcaacttcctc atggtgctgggcaagggcagcttcgggaaggtgatgctggcggacaggaaggggacggag gagctgtacgccatcaagatactgaagaaggacgtggtgatccaggacgacgatgtggag tgcaccctggtggagaagcgggtgctggccctgccggacaagcccccgttcctgacgcag ctgcactcctgcttccagacggtggatcggctgtacttcgtcatggaatacgtcaacggc ggggacctcatgtaccacatccagcaagtaggaaaatttaaggaaccgcaagcagtgttc tacgcagcagagatttccattgggttgttctttcttcataaaagaggcatcatttataga gacctgaagttagataacgtcatgctggattcagaaggacacatcaagattgcggacttt gggatgtgtaaggagcacatgatggacggggtcacgaccaggaccttctgcgggacccca gattacatcgccccggagataatcgcttatcagccgtatgggaaatccgtggactggtgg gcctacggcgtcctgttatatgaaatgctggccgggcagcctccgtttgatggcgaggat gaagacgagctgtttcagtccatcatggagcacaacgtctcgtacccgaagtccttgtcc agggaggccgtctccatctgcaaagggctgatgaccaaacaccccggcaagcggctgggc tgcgggcccgagggagagcgggacgtgcgggaacacaccttcttccggaggatcgactgg gagaagctggagaacagggaggtccagccgcccttcaagcccaaagtgtgcggcaaagga gcagaaaacttcgacaagttcttcacgcgagggcagcctgtcttaacgccacccgatcag ctggtcatcgctaacatcgaccagtctgattttgaagggttctcatatgtcaacccccag ttcgtgcaccccatcctacagagcacagtatga

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