Orcinus orca (killer whale): 101277232
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Entry
101277232 CDS
T05247
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01524
Platinum drug resistance
oor04010
MAPK signaling pathway
oor04071
Sphingolipid signaling pathway
oor04141
Protein processing in endoplasmic reticulum
oor04210
Apoptosis
oor04530
Tight junction
oor04668
TNF signaling pathway
oor04714
Thermogenesis
oor04722
Neurotrophin signaling pathway
oor04932
Non-alcoholic fatty liver disease
oor04936
Alcoholic liver disease
oor05010
Alzheimer disease
oor05012
Parkinson disease
oor05014
Amyotrophic lateral sclerosis
oor05016
Huntington disease
oor05017
Spinocerebellar ataxia
oor05022
Pathways of neurodegeneration - multiple diseases
oor05208
Chemical carcinogenesis - reactive oxygen species
oor05417
Lipid and atherosclerosis
oor05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101277232 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101277232 (MAP3K5)
04668 TNF signaling pathway
101277232 (MAP3K5)
04071 Sphingolipid signaling pathway
101277232 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
101277232 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
101277232 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101277232 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
101277232 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101277232 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
101277232 (MAP3K5)
05012 Parkinson disease
101277232 (MAP3K5)
05014 Amyotrophic lateral sclerosis
101277232 (MAP3K5)
05016 Huntington disease
101277232 (MAP3K5)
05017 Spinocerebellar ataxia
101277232 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
101277232 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101277232 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
101277232 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101277232 (MAP3K5)
04932 Non-alcoholic fatty liver disease
101277232 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101277232 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101277232 (MAP3K5)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
101277232 (MAP3K5)
Protein kinases [BR:
oor01001
]
Serine/threonine kinases: STE group
STE11 family
101277232 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Fungus-induced
Motif
Other DBs
NCBI-GeneID:
101277232
NCBI-ProteinID:
XP_004263831
LinkDB
All DBs
Position
12:26400633..26611585
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPLAEGGSYRRGGAAAAAEGEENQLPPPPPGSFWNVESAAAPGVACP
SATPGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCLRQACETVGATLE
TLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTN
SDSLQSLKEIICQKNTMCTGNYTFIPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASCSQYFRESILNDIRKARNLYTGKELAVELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFMDSESRDHGASWFKKAFESEPT
LQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSVSKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRNTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDMSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRDCANDLLMDDFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVRGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLVASLGEFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEEQPSNQTVR
RPHVVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIDIPGLPACHLNSPGANTEDSELTEWLRENGADEDTIS
RFLAEDYSLADVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQT
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctctgtgccacccttggccgagggcggc
agctaccggaggggaggagcggcggcggccgccgagggcgaggagaaccagctgccgccg
ccgccaccgggcagcttctggaacgtggagagtgccgccgcccctggtgttgcgtgtccc
agtgccacccccgggagcagcgccacccggtgccggggcaactctggtggcggaggaggc
cgacggaccacggtggcatatgtcatcaacgaagcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagtgcctgcggcaggcgtgcgagacggtgggcgccaccctggag
accctgcatttcgggaaactggactttggggaaactgcggtgttggaccgtttttacaat
gcagatattgccgtggtggagatgagtgatgccttccggcagccgtctttattttaccac
cttggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgatactaat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacatttattccttacatgataactccacataacaaggtctactgctgtgatagc
agcttcatgaagggcttgacagagctcatgcagccgaactttgagctgctccttggaccc
atctgcttacctcttgtggatcgtttcattcaacttttgaaggtggcacaagcaagttgc
agccagtatttccgggaatctatactcaatgatatcaggaaagctcgtaacttatacact
ggtaaagaactggcagttgaattggcaagaattcgacagcgagtggataatattgaagtc
ctgacagcagatattgtcataaatctgttactttcctacagagatatccaggactatgat
tctattgtgaagctcgtagagactttagaaaagctgccaacctttgatttggcctcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaatctccctggagataga
gcaaaagctcttgacattatgattcccctggtgcaaagtgaagggcaagttgcttcagat
atgtattgcctcgttggtcgaatctacaaagatatgtttttggactctaatttcatggat
tctgaaagtagagaccatggagcttcttggttcaaaaaggcatttgaatctgagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcatctgggcaccagttcgaatct
tcctttgagctccgaaaagttggggtgaagctcagtagccttcttggtaaaaagggaaac
ttggaaaagctccagagctactgggaagttggatttttcctgggagcaagtgtcctggcc
aatgaccacttgagagtcattcaagcatctgaaaagctttttaaactgaagacacctgca
tggtacctcaagtctattgtagagacgattttgatatataagcattttgtgaaactgact
tcagaacagcccgtggccaagcaggaacttgtggacttctggatggatttcctggttgag
gccacaaagacagatgtcactgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcgtatttgtctatcaacaatgaagtggaggaaaagacaatatctatc
tggcacgtacttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtgtttctaaatttgaagaacgatgctgttttctttatgtgcttcac
aattctgatgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccattactgaagagaaggggagaaatacagaggaaggagattgtgaaggt
gactccctggagtatgactatgaatatgacgaaaatggtgacagagtcgttttaggaaaa
ggcacttatgggatagtttatgcaggtcgagatatgagcaaccaagtcagaatcgccatt
aaggaaatcccagagagagatagcagatactcccagcccctacatgaagaaatagcactg
cataagcatctgaagcacaaaaatattgttcagtatctgggctctttcagtgagaatggt
ttcattaaaatcttcatggagcaggtcccagggggaagtctttcagctctccttcgttcc
aaatggggcccactgaaagacaacgagcaaacaattggcttttataccaagcaaatactg
gaaggattaaaatacctccatgacaatcagatagttcaccgggatataaagggtgacaat
gtgttgattaatacctatagtggtgttctcaagatctctgatttcgggacatcaaagagg
cttgctggcataaatccatgtactgaaacttttactggtacccttcagtatatggcacca
gaaataatagataaaggaccaagaggctacgggaaagcagcagacatttggtctttgggc
tgcacgatcattgaaatggccactggaaaaccacccttttatgaactgggggaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagatcccagagtccatgtcg
gcagaggccaaagcgttcatattgaaatgttttgaaccagaccctgacaagagagactgt
gctaacgacttgcttatggatgatttcttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagctctttcagctggatcgaatgagtatcttaggagcatctccctgcca
gtgcctgtcctggtggaggacaccagcagtagcagtgagtacggctcagtttctccagac
acggagttaaaggtggatcccttctctttcaaaacaagagccaaatcctgcggagaaaaa
gatgtcagaggaatacggacgctctttctgggcatccctgacgaaaattttgaagaccac
agcgctccaccttctcctgaagaaaaagattccggattctttatgctgaggaaggacagt
gagagacgggccacgcttcacaggatcctgacggaagaccaagacaaagttgtgagaaac
ttaatggaatctttggctcagggggccgaagaacctaagctaaaatgggagcacatcaca
accctcgtcgcgagcctcggagaatttgtgaggtccactgaccggaagatcatagccacc
accctgtccaagctgaagctggagctggactttgacagccacggcattagtcaagttcag
gtggtgctcttcggttttcaagatgctgtcaataaagttcttcggaatcataatatcaag
ccacactggatgtttgccttagacagtatcatccgaaaggcggtgcagacagccattacc
attctggttccagaactgaggccacattttagccttgcatctgagagtgataccgccgat
caagaagacttggatgcagaagatgaccatgaagaacagccttcaaatcaaactgtccga
agacctcatgtggtccttgaagatgctgtggccacctcaggggtgagcacactcagttct
actgtatcccacgactcccagagtgctcaccgatcgctgaatgtacagcttggaaggatg
aaaatagaaacaaatagattactggaagaattggttcagaaagagaaagaactacaagca
cttcttcatcaagctattgaagaaaaagaccaagaaattaagcacctgaagcttaagtcc
caaccaatagatattcctgggttgcctgcgtgtcacctgaattctcctggtgcaaatact
gaagattccgaacttactgaatggctgagagaaaatggagccgatgaagacactataagt
cggtttttggccgaggattattcactagcagatgttctctactacgttacacgtgacgat
ttaaaatgcctgagactaaggggagggatgctgtgtacactgtggaaagccatcactgac
tttcgagacaaacagacttga
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