Orcinus orca (killer whale): 101287044
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Entry
101287044 CDS
T05247
Symbol
HSD17B8
Name
(RefSeq) (3R)-3-hydroxyacyl-CoA dehydrogenase isoform X1
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00061
Fatty acid biosynthesis
oor00140
Steroid hormone biosynthesis
oor01100
Metabolic pathways
oor01212
Fatty acid metabolism
Module
oor_M00873
Fatty acid biosynthesis in mitochondria, animals
oor_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101287044 (HSD17B8)
00140 Steroid hormone biosynthesis
101287044 (HSD17B8)
Enzymes [BR:
oor01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
101287044 (HSD17B8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
101287044 (HSD17B8)
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Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
RmlD_sub_bind
Motif
Other DBs
NCBI-GeneID:
101287044
NCBI-ProteinID:
XP_004267797
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Position
10:65579344..65581618
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AA seq
259 aa
AA seq
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MASQLRLRFALALVTGAGSGIGRAVGVRLAAEGATVAACDLDGEAARETVRLLGGPGSHE
GAPRGAHAAFQADVSEAGAVRRLLDQVQACFSRPPSVVVSCAGITRDEFLLHMSEDDWDK
VIAVNLKGIFLVTQAAAQALVSSGCPGSIINISSIVGKVGNVGQTNYAASKAGVVGLTQT
AARELGRHGIRCNSVLPGFIKTPMTQKVPQKVLDKVTGMIPVGHMGDPEDVADVVAFLAS
EDSGYITGASVEVTGGLFM
NT seq
780 nt
NT seq
+upstream
nt +downstream
nt
atggcgtctcagctccggcttcgcttcgcgctggctctggtcacaggtgctggtagtggc
atcggccgagcagtgggtgtgcgcctggccgctgagggggccactgtggccgcttgcgac
ctggacggggaagcggcacgggagacggtgcggctgctgggagggccggggagccacgag
ggggcaccccgcggggcccacgcagccttccaggctgacgtgtccgaggccggggccgtc
aggcgcctgctggatcaagtgcaggcctgcttttctcgcccgccatctgtcgttgtgtcc
tgtgcgggcatcaccagggatgagtttctgctccacatgtctgaggatgactgggacaaa
gtcatagctgtcaacctcaagggcatctttctagtcactcaggctgcagcccaagccctg
gtgtccagtggctgtcctggctccatcatcaacatcagtagcatcgtagggaaggtgggg
aacgtgggacagacaaactacgcagcatccaaggctggagtggttgggctgacccagact
gcagcccgggagcttggacgacatgggatccgctgtaactctgtcctcccagggttcatt
aaaacacccatgacacagaaagtgccacagaaagtactggacaaggtgactggaatgatc
ccagtgggacatatgggggaccctgaggatgtggcagatgtggtcgcgttcttggcatct
gaagacagtggatacatcacaggggcgtcagtggaagtcactggaggtcttttcatgtaa
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