Orcinus orca (killer whale): 101288495
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Entry
101288495 CDS
T05247
Symbol
PDHA2
Name
(RefSeq) LOW QUALITY PROTEIN: pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00010
Glycolysis / Gluconeogenesis
oor00020
Citrate cycle (TCA cycle)
oor00620
Pyruvate metabolism
oor00785
Lipoic acid metabolism
oor01100
Metabolic pathways
oor01200
Carbon metabolism
oor01210
2-Oxocarboxylic acid metabolism
oor04066
HIF-1 signaling pathway
oor04922
Glucagon signaling pathway
oor05230
Central carbon metabolism in cancer
oor05415
Diabetic cardiomyopathy
Module
oor_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101288495 (PDHA2)
00020 Citrate cycle (TCA cycle)
101288495 (PDHA2)
00620 Pyruvate metabolism
101288495 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101288495 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101288495 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101288495 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101288495 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101288495 (PDHA2)
Enzymes [BR:
oor01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101288495 (PDHA2)
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Motif
Pfam:
E1_dh
Motif
Other DBs
NCBI-GeneID:
101288495
NCBI-ProteinID:
XP_012391091
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Position
4:16395526..16396700
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AA seq
360 aa
AA seq
DB search
MRKMLAAAVSSVLSVVIQKPANRVLVASCNYSNDATFEIKKCDLYRLEEGAPVTAVLTRE
DGLKYYRMMQNICRMELKADQLXKQKFIRGFCHLCDGQEACCVGLEAGLNPTDHVIASFQ
AHGXMCTCGLSVPSILAELTGRRGGCVEGEGGSMHMYANNFYGGNGTVGAQGLLGAAYNM
TAVWNLPCIFICENNRYGMGISVERAAANTDYYKRGSFIPGLKVDGMEVLCVWEATKVAA
DYCRSGKGPILMELLTYHYYGHSMSHPGISYRTREEVQNLSSKSHPIMLLKDKMVNNKLA
SIEELKEIDVEVRKEIDAAAQFAITDPEPPLEELSHHIYSTNPPFEIRDANQWIRFKSVS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggctgctgctgtctctagcgtgctgtctgttgtcatccagaagccc
gctaacagggtgcttgtggcatcctgtaactattcaaatgatgctacatttgagattaag
aaatgtgatctttatcggttggaagagggtgcccctgtcaccgcagtgctcacccgggag
gatggactcaaatactacaggatgatgcagaacatttgtcgaatggaattgaaggcggat
cagttgtaaaaacagaaatttattcgtggtttctgtcacttgtgtgatggtcaggaagct
tgttgtgtgggtcttgaggctgggctaaatcccacagatcatgttattgcatcctttcag
gctcacggcntcatgtgtacttgtggactttctgtcccatcaattctagcagagctgaca
ggtcgaagaggtggctgtgttgaaggagaaggagggtcaatgcatatgtatgccaataac
ttctatggaggcaatggcactgttggcgctcagggactgctgggagctgcttataatatg
acagctgtgtggaatttaccttgtattttcatctgtgagaataaccgctatggaatggga
atatctgttgagagagctgcagccaacactgattactacaagagaggcagtttcatccct
ggcctaaaggtagatggaatggaggttctgtgtgtttgggaggcaactaaggttgcagct
gactattgtagatctggaaaggggcccatactgatggagctgctgacataccattattat
ggacacagtatgagtcaccctggaatcagttatcgtacacgagaagaagttcagaattta
agcagtaagagccatcctatcatgcttctcaaagataaaatggtaaacaacaaacttgcc
agtattgaagaattgaaggaaattgatgttgaagtgaggaaagaaattgatgctgctgct
cagtttgctataaccgatcctgaaccacctttggaagaattaagccatcacatctacagc
actaatccaccttttgaaattcgtgatgcaaatcagtggatcaggtttaagtcagtcagt
taa
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