Pseudomonas aeruginosa M18: PAM18_3259
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Entry
PAM18_3259 CDS
T01973
Symbol
acnB
Name
(GenBank) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
paf
Pseudomonas aeruginosa M18
Pathway
paf00020
Citrate cycle (TCA cycle)
paf00630
Glyoxylate and dicarboxylate metabolism
paf00640
Propanoate metabolism
paf01100
Metabolic pathways
paf01110
Biosynthesis of secondary metabolites
paf01120
Microbial metabolism in diverse environments
paf01200
Carbon metabolism
paf01210
2-Oxocarboxylic acid metabolism
paf01230
Biosynthesis of amino acids
Module
paf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
paf_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
paf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
PAM18_3259 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
PAM18_3259 (acnB)
00640 Propanoate metabolism
PAM18_3259 (acnB)
Enzymes [BR:
paf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
PAM18_3259 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
PAM18_3259 (acnB)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AEO75742
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Position
3642127..3644736
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AA seq
869 aa
AA seq
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MLEAYRKHVEERAAQGVVPQPLNAEQTAGLVELLKNPPAGEEEFLLDLITNRVPPGVDEA
AYVKAGFLSAIVKGEATSPLIDKQRAAELLGTMQGGYNIATLVELLDDAELANTAAEQLK
HTLLMFDAFHDVAERAKKGNAAAKSVLQSWADGEWFKAKPEVPEKLTLTVFKVPGETNTD
DLSPAPDAWSRPDIPLHALAMLKMARDGIEPVQPGSVGPLKQIEAVKAKGFPVAYVGDVV
GTGSSRKSATNSVLWFFGDDIPFVPNKRAGGFCFGTKIAPIFYNTMEDAGALPIEFDCTN
LAMGDVIDVYPYEGKVVRHDSGEVVTTFELKTPVLLDEVRAGGRIPLIVGRGLTEKARAE
LGLGASDLFRKPEAPADSGKGFTLAQKMVGRACGLPEGQGVRPGTYCEPKMTTVGSQDTT
GPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPIDVKTHHTLPDFIMTRGGVSLRPGDG
IIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFK
GKLQPGITLRDLVHAIPYYAIQQGLLTVEKKGKKNIFSGRILEIEGLNDLTVEQAFELSD
ASAERSAAGCTIKLPEQAIAEYLKSNITLLRWMIGEGYGDPRTLERRAQAMEAWLAKPEL
LEADKDAEYAAVIEIDLADVKEPVLCAPNDPDDARLLSSVQGRKIDEVFIGSCMTNIGHF
RAAGKLLDKVKGGIPTRLWLAPPTKMDAHQLTEEGYYGIYGKAGARMEMPGCSLCMGNQA
RVQTGSTVVSTSTRNFPNRLGDATDVFLASAELAAVSSILGKLPTVEEYMAYAKDIDSMA
ADVYRYLSFDQIAEFREAAANAKIPVVQA
NT seq
2610 nt
NT seq
+upstream
nt +downstream
nt
gtgcttgaagcctaccgcaaacacgtagaagagcgtgccgcccagggtgtcgtgccccaa
ccgctgaacgccgaacagaccgcaggcctggtcgagctgctgaagaacccgccggccggc
gaagaagaattcctccttgacctgatcaccaaccgcgtaccgccgggcgtcgacgaagcc
gcctacgtcaaggccggtttcctttccgccatcgtcaagggcgaagccacctcccccctt
atcgacaagcaacgtgccgccgagctgctgggcaccatgcagggcggctacaacatcgcc
accctggtcgagctgctggacgacgccgaactggccaacaccgccgccgaacagctgaag
cacaccctgctgatgttcgacgccttccacgacgtcgccgagcgcgccaagaagggcaat
gccgcggccaagtccgtgctgcaatcctgggccgatggcgagtggttcaaggccaagccg
gaagtcccggaaaagctgactctcaccgtattcaaggtccccggcgaaaccaacaccgac
gacctctccccggcccccgacgcctggtcgcgcccggacatcccgctgcacgccctggcc
atgctgaagatggcccgcgacggcatcgagccggtccagccgggttcggtcggtccgctg
aagcagatcgaagcggtcaaggccaagggcttcccggtcgcctacgtcggcgacgtggtc
ggcaccggttcctcgcgcaaatccgccaccaactcggtgctgtggttcttcggcgacgac
attccgttcgtgccgaacaagcgtgccggcggcttctgcttcggcaccaagatcgcaccg
atcttctacaacaccatggaagatgccggcgccctgccgatcgagttcgactgcaccaac
ctggccatgggcgacgtcatcgacgtatacccctatgaaggcaaggtcgttcgccacgac
agcggcgaagtggtcaccaccttcgagctgaagaccccggtcctgctcgacgaagtccgc
gccggcggccgtatcccgctgatcgtcggccgtggcctgaccgagaaggcccgcgccgag
ctgggcctgggcgcctccgacctgttccgcaagccggaagcaccggccgatagcggcaag
ggcttcaccctggcgcagaaaatggtcggccgcgcctgcggtctgccggaaggccagggc
gtgcgcccgggcacctactgcgaaccgaagatgaccaccgtcggttcccaggacaccacc
ggcccgatgacccgcgacgaactgaaggacctcgcctgcctcggcttctccgccgacctg
gtgatgcagtccttctgccacaccgcggcctatccgaagccgatcgacgtcaagacccac
cacaccctgcccgacttcatcatgacccgtggcggcgtgtcgctgcgtccgggcgacggc
atcatccacagttggctgaaccgcatgctgctgcccgataccgttggtaccggcggcgac
tcgcacacccgcttcccgatcggcatctcgttcccggccggctccggcctggtggccttc
gccgccgccaccggcgtgatgccgctggacatgccggagtcggtgctggtgcgcttcaag
ggcaagctgcaaccgggcatcaccctgcgtgacctggtccatgcgatcccttactacgcg
atccagcagggcctgctgaccgtcgagaagaagggcaagaagaacatcttctccggccgc
atcctcgagatcgaaggcctcaacgacctgaccgtggagcaggccttcgagctgtccgac
gcctcggccgagcgttccgccgccggctgcaccatcaagctgccggaacaggcgatcgcc
gagtacctgaagtccaacatcaccctgctgcgctggatgatcggcgaaggctacggcgac
ccgcgcaccctggagcgtcgcgcccaggcgatggaagcctggctggccaagccggagctg
ctggaagccgacaaggacgccgagtacgccgcggtgatcgagatcgacctggccgacgtc
aaggagccggtgctctgcgcgccgaacgatccggacgacgcgcgtctgctgtcgagcgta
cagggccgcaagatcgatgaagtgttcatcggctcctgcatgaccaacatcggtcacttc
cgcgccgccggcaagctgctggacaaggtcaagggcggcatcccgacccgtctgtggctg
gctccgccgaccaagatggacgcccaccagttgaccgaggaaggctactacggcatctac
ggcaaggctggcgcgcgcatggaaatgccgggctgctcgctgtgcatgggcaaccaggct
cgcgtccagaccggttccaccgtagtctccacttcgacccgtaacttcccgaaccgtctg
ggcgatgccaccgatgtgttcctggcatcggccgagctggcggcggtctcctcgatcctc
ggcaaactgccgaccgtggaggagtacatggcctacgcgaaggacatcgacagcatggct
gccgacgtctaccgctacctgagcttcgaccagatcgccgagttccgcgaagcggctgcg
aacgccaagatcccggtcgtccaggcctga
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