Pyrobaculum aerophilum: PAE2644
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Entry
PAE2644 CDS
T00073
Name
(GenBank) pyruvate dehydrogenase E1 alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pai
Pyrobaculum aerophilum
Pathway
pai00010
Glycolysis / Gluconeogenesis
pai00020
Citrate cycle (TCA cycle)
pai00620
Pyruvate metabolism
pai00785
Lipoic acid metabolism
pai01100
Metabolic pathways
pai01110
Biosynthesis of secondary metabolites
pai01120
Microbial metabolism in diverse environments
pai01200
Carbon metabolism
pai01210
2-Oxocarboxylic acid metabolism
Module
pai_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
PAE2644
00020 Citrate cycle (TCA cycle)
PAE2644
00620 Pyruvate metabolism
PAE2644
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PAE2644
Enzymes [BR:
pai01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
PAE2644
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AAL64338
UniProt:
Q8ZUR8
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All DBs
Position
1572744..1573862
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AA seq
372 aa
AA seq
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MLEISLEIPTQFKTEVKEPQVFRVLGQDGSPLETYEVGYKPSEGELAKAYRWMVLGRVLD
RYALMYHRMGKVKSTYGPHEGHEAADAGTALALRPEDWVAPYYRNLTLLIARGVPLEVIW
AKFFAKLGDPDKGRNLTIEWGGFKQWRILSIGAPIGHQYIYAAGFAYALKYLKKKEVVAA
YIGDGGTSTNGFHTGLNFAGVFKVPAAFFIYNNQYAISVPVSIQTAVSRLSTKAAAYGLV
GVSADGMDLLAVVKTAMWAVEKARRGEPTLVEYVMYRFGPHTTADDPLTKYRDPKEVEEY
RRWDPLARLEKFLIRQGIYSEGDVKTIWEEAEREVKEAAKEAEALPDVPAEELINDVYSF
VPKSLREWLEWL
NT seq
1119 nt
NT seq
+upstream
nt +downstream
nt
atgttagaaataagtttagaaattcctacacaatttaaaacagaggttaaagagcctcaa
gtctttagagtgctgggccaagacggctctccgctggagacgtatgaagtgggctataag
cccagcgagggggagttggccaaggcgtataggtggatggtattggggagggtgttggac
agatacgccttgatgtatcacagaatgggcaaggtgaaatccacctacggcccccacgag
ggccacgaggccgcagacgcgggcactgccctggcgctgaggcctgaggactgggtggcg
ccttattacagaaatttaactctgctcatagccaggggcgtcccgttggaggttatatgg
gctaagttcttcgccaagttgggggatccggacaagggaaggaatttaacaattgagtgg
ggcgggtttaaacagtggaggattttatccatcggcgcgcccattggccaccagtatata
tacgcagctggcttcgcctacgccttaaagtatttaaagaaaaaagaggtggtggccgcc
tatataggagacggcgggacttccacaaacggcttccacacaggcttgaacttcgcagga
gtgtttaaagttcccgcggcctttttcatttacaacaaccagtacgccatatctgtccca
gtctctatacaaaccgccgtctctaggctgtccactaaagccgcggcgtacggcctggtg
ggggtttccgcagacggcatggatttgctggcggtggtgaagacggcaatgtgggcggtg
gagaaggccaggaggggggagcctacgttagtggaatacgtcatgtatagattcggcccc
cacaccacagcggatgatcccttgactaagtacagagatcccaaagaggtagaggagtac
aggaggtgggaccccctggctaggcttgagaaatttttaatccgccaggggatttacagc
gagggcgacgtgaagacaatttgggaggaggccgagagggaggttaaagaggcggcaaaa
gaggccgaggccctgcccgatgtgcccgcggaggagcttataaacgatgtatatagcttt
gtgcccaagtcgctgagggagtggctggagtggttatga
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