Cutibacterium acnes SK137: HMPREF0675_4049
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Entry
HMPREF0675_4049 CDS
T01215
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
pak
Cutibacterium acnes SK137
Pathway
pak00010
Glycolysis / Gluconeogenesis
pak00020
Citrate cycle (TCA cycle)
pak00620
Pyruvate metabolism
pak00785
Lipoic acid metabolism
pak01100
Metabolic pathways
pak01110
Biosynthesis of secondary metabolites
pak01120
Microbial metabolism in diverse environments
pak01200
Carbon metabolism
pak01210
2-Oxocarboxylic acid metabolism
Module
pak_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pak00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HMPREF0675_4049 (aceE)
00020 Citrate cycle (TCA cycle)
HMPREF0675_4049 (aceE)
00620 Pyruvate metabolism
HMPREF0675_4049 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HMPREF0675_4049 (aceE)
Enzymes [BR:
pak01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HMPREF0675_4049 (aceE)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
DUF2470
Motif
Other DBs
NCBI-ProteinID:
ADD99161
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All DBs
Position
1074281..1077034
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AA seq
917 aa
AA seq
DB search
MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHS
RLGLSALTSTDYINTIAAEDEEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHI
STYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGMYARAFLEGRLSEDDLDGFRQ
EKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMDSIYQASMNKYLTNRGVKDCADQHVW
AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGA
GWNVIKVIWGSGWDPLLQADRDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTA
KMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTVVLACTIKGYDLGTHFAGRNA
THQMKKLALDDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF
VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPD
EARTFGMDSFFPTIKIYNPHGQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAA
GSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRGFIIGATAGRTTLTGEGTQHM
DGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE
PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADV
WSVTSWNNLRRDAMEAEEQTFLHPEQGRRTPYITQCLADAPGPVVATTDYTRQVPDQIAQ
WVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQMLVERGEVPEDWPAKAAEKY
DLLNVNAGASGNAGGDA
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
gtgatcccacgcgaagaacgcggaccagtcctcaacggacttccgacaaccctgcctgac
gtcgatcccgaggagactcaggagtggatcgagtccctcgacaagatggtcgagactgat
ggtccgaatcgtgcccggatcgtgctgctcaagatgttggagcgggctcgtagccacagt
cgtctcgggctgtcagcgctcacctccaccgactacatcaacaccattgcagccgaggac
gaggaagaataccccggcgacgccgagatcgagcggaacatccgtcgtttgctgcgctgg
aattccgccattaccgtgcatcgcgcgcagcgtcccggtattggcgtcggcggtcatatc
tccacctatgcctctgccgtgaccctctacgaggtcggtcagaaccacttctggcgcggg
caggacgcccccggcggcggtgaccaagttttcttccaggggcacgccgcgcccggtatg
tacgctcgcgcgttcttggaggggcgtctcagcgaggacgatctcgatgggttccgtcag
gagaagtcgaaggccgggcatggtctaccctcttacccgcaccctcgcatgttgcccgac
ttctggcagttcccgacggtgtcgatgggtctgggcccgatggattccatttaccaggcg
tctatgaataagtacctcaccaatcgcggtgtcaaggactgcgcagatcagcacgtgtgg
gctttccttggcgacggtgagatggacgagccggagtcgcgcggattcctgcaggtcgct
gccaacgaggagctcgacaacctcaccttcgtcatcaactgcaacctgcagcgtctagac
gggccggtgcgtggcaacggcaagattgtccaggaacttgaggctgtcttccgtggtgct
ggctggaacgtcatcaaggtcatttggggatccggctgggacccgttgctgcaggcagac
cgtgacggtgccctcgttgatatcatgaacaacacccgtgatggcgactaccaaaccttt
aaggccaacgacggcgcctatgtccgcgagcacttctttggccgcgacccgcgcactgcc
aagatggtcgacaagtggactgacgaacagatttgggcgttacgccgtggcggtcacgac
taccgcaagatttacaacgcctacaaggcggctacgcagttcaagggagcgccgaccgtg
gtgcttgcctgcactattaaaggttacgatcttggtactcactttgcgggccgcaacgct
acccaccagatgaagaagctggcccttgacgacctcaagcagttccgcgatcgtctcgaa
attccgatttcggacaaggtgctggaggccgacccctaccgtgctccctacttccatccc
ggagccgatgacgagcgcatccagtacctcatggagcgtcgtcgtgctctcggcggtttc
gtgccggagcgccgtaccaggcacacgccactacccatcccggcgcagaaggccttcgat
ggtgtcaagcgtgggtcgggcaaacaggaggtcgccaccacgatggccttcgtgcgtctg
ctcaaggaccttatgcgcgacaagaatttcgctccgcacgtcgtcccgatcattcctgac
gaggcccgtacctttggcatggactcgttcttcccgacgatcaagatctacaatcctcac
ggccagaactacacccctgtcgaccacgagctcatgctcagctaccgcgaggccaagaac
gggcagatcattcacactggcatcaatgaggctggttcggcggctgctttcattgccgca
ggctcggcatactccactcagggcgtgccgatggtgccgatctacctgttctactcgatg
ttcgggttccagcgtaccggtgattctttctgggcagctggtgatcagatgacgagggga
ttcattattggcgccactgccggacgcaccacgctgaccggtgagggcacccagcacatg
gatggccattcgccggttctggctgcgacgaacccagctgtcatctcctacgatccggct
tattcttacgagatctcccacattgttcaggcaggtctggagcacatgtacggcgagaac
gccgaagacgtcatgtactacctgacggtgtacaacgagccgatcgtccagccggctgag
ccagagggcgttgacgccgagggcatcgtcaagggcatgtacctgctctcgaagggctcc
tttgagggcgtcggcgaggatgcccgccgcgttcagctgctggcctccggcgtcgccgtg
ccgtgggccattgaggctcagcagctccttaagggtgactttggcgttgttgccgacgtg
tggtcggtgacgtcgtggaacaacctacgtcgtgacgctatggaggccgaggaacagact
ttcctacaccccgaacagggcaggcgcaccccgtatatcacccaatgcctggccgacgcc
cctggtccagtcgttgcgaccaccgattacacgcgtcaggtgcccgatcagatcgcccag
tgggtgccgggggattatgcctccttaggtgctgacggattcgggttctccgacacccgt
gcggcagcgcgccgattcttccacatcgatggaccgtccatgacagtgcgtgccctccag
atgctcgtcgagcgtggtgaggttcccgaggactggcctgccaaggctgccgagaagtac
gacctcctcaacgtcaacgcgggggcgtccggtaacgctggtggcgacgcctga
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