Cutibacterium acnes SK137: HMPREF0675_5145
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Entry
HMPREF0675_5145 CDS
T01215
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
pak
Cutibacterium acnes SK137
Pathway
pak00280
Valine, leucine and isoleucine degradation
pak00640
Propanoate metabolism
pak00785
Lipoic acid metabolism
pak01100
Metabolic pathways
pak01110
Biosynthesis of secondary metabolites
pak01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
pak00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HMPREF0675_5145 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HMPREF0675_5145 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HMPREF0675_5145 (pdhA)
Enzymes [BR:
pak01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HMPREF0675_5145 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ADE00127
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Position
complement(2204440..2205585)
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AA seq
381 aa
AA seq
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MTETICADEGGTDPFVLPARQHPVNRPDPAMVRILDEQGRLTTHPDFPVDLVDDDLVKAL
EMMVMTRRFDVEATALQRHGELGLWPPLLGQEATQAGAWLALREGDQVFPTYREQGLAHA
MGVSLADILGAWDGTSHCGWDTVATHFSAYPVMIGSGTLHAVGYAMGVQRDVEAGGDPAA
VLDFHGDGAMSEGDTNEAYVFAASMNAPVVFVCVNNQWAISEPTTVQSPTSLFRRATGFG
IPAVQVDGNDVIAMMAVLRSALEYARSGKGPVFVEAWTYRMGAHTTTDDPTRYRTAEEES
TWGKTDPIVRLRTYLQNRGIINQVWLDGLAEREDAFGAEVRAAVHENATPVMADLMADVY
AEPTPDVLADAEEIASWEEDK
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgagaccatttgtgccgacgaaggcggcacggatccgttcgtccttccggcgcgg
caacaccccgttaatcgtcctgatcctgcaatggtgcggatcctcgacgagcagggacgc
ctcaccacacaccccgactttcctgttgacctggtcgacgacgacctcgtcaaggctctc
gagatgatggtcatgacgcgacgcttcgacgtcgaggctaccgccctgcagcgccacggc
gaattgggtttgtggccgccgctattgggacaggaggccacccaggctggcgcttggttg
gcactgagagagggagaccaggtgtttcccacctaccgcgagcagggcctggcccacgcc
atgggcgtcagtctggctgacatccttggagcttgggacgggacctctcactgcggctgg
gataccgtcgcgacccacttcagcgcatatccagtgatgatcgggtcgggaaccctgcat
gccgtcggctatgccatgggtgtccagcgtgacgtcgaggctggaggtgatccggctgcc
gtgctggatttccacggtgacggcgcgatgagcgagggggacacgaacgaggcttatgtt
tttgcggcttcgatgaacgcccccgtggtattcgtatgcgtcaataaccagtgggcgatt
tcagagccgaccacggtgcagtcgcccacgtctcttttccgccgcgccaccgggttcggc
atccctgccgtgcaagtcgacggcaacgacgtcatcgccatgatggccgtgctgcgatcg
gccctcgaatatgcccgtagcggaaaggggccggtgttcgtcgaggcgtggacctaccgg
atgggtgctcacaccaccaccgacgaccccacccgctaccgcaccgcagaagaggagtcg
acgtggggtaagaccgaccccatcgtccggctgcgcacgtatttgcagaaccgcgggatt
atcaaccaggtgtggcttgacggcctcgctgagcgtgaggacgccttcggtgctgaggtt
cgcgctgctgttcacgagaatgccacgcctgtgatggctgaccttatggcggacgtgtac
gccgagccgacccccgacgtcctggctgacgccgaggaaatcgcgtcgtgggaggaggat
aagtga
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