Pteropus alecto (black flying fox): 102887497 Help Entry 102887497         CDS       T02993                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism pale  Pteropus alecto (black flying fox) Pathway pale00230   Purine metabolism pale01100   Metabolic pathways pale01522   Endocrine resistance pale04015   Rap1 signaling pathway pale04020   Calcium signaling pathway pale04022   cGMP-PKG signaling pathway pale04024   cAMP signaling pathway pale04062   Chemokine signaling pathway pale04072   Phospholipase D signaling pathway pale04114   Oocyte meiosis pale04211   Longevity regulating pathway pale04213   Longevity regulating pathway - multiple species pale04261   Adrenergic signaling in cardiomyocytes pale04270   Vascular smooth muscle contraction pale04371   Apelin signaling pathway pale04540   Gap junction pale04611   Platelet activation pale04713   Circadian entrainment pale04714   Thermogenesis pale04720   Long-term potentiation pale04723   Retrograde endocannabinoid signaling pale04724   Glutamatergic synapse pale04725   Cholinergic synapse pale04727   GABAergic synapse pale04750   Inflammatory mediator regulation of TRP channels pale04911   Insulin secretion pale04912   GnRH signaling pathway pale04913   Ovarian steroidogenesis pale04914   Progesterone-mediated oocyte maturation pale04915   Estrogen signaling pathway pale04916   Melanogenesis pale04918   Thyroid hormone synthesis pale04921   Oxytocin signaling pathway pale04923   Regulation of lipolysis in adipocytes pale04925   Aldosterone synthesis and secretion pale04926   Relaxin signaling pathway pale04927   Cortisol synthesis and secretion pale04928   Parathyroid hormone synthesis, secretion and action pale04934   Cushing syndrome pale04935   Growth hormone synthesis, secretion and action pale04970   Salivary secretion pale04971   Gastric acid secretion pale04972   Pancreatic secretion pale04976   Bile secretion pale05032   Morphine addiction pale05142   Chagas disease pale05146   Amoebiasis pale05163   Human cytomegalovirus infection pale05166   Human T-cell leukemia virus 1 infection pale05200   Pathways in cancer pale05207   Chemical carcinogenesis - receptor activation pale05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pale00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102887497 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102887497 (ADCY1)    04371 Apelin signaling pathway     102887497 (ADCY1)    04020 Calcium signaling pathway     102887497 (ADCY1)    04072 Phospholipase D signaling pathway     102887497 (ADCY1)    04024 cAMP signaling pathway     102887497 (ADCY1)    04022 cGMP-PKG signaling pathway     102887497 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102887497 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     102887497 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102887497 (ADCY1)    04062 Chemokine signaling pathway     102887497 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     102887497 (ADCY1)    04923 Regulation of lipolysis in adipocytes     102887497 (ADCY1)    04912 GnRH signaling pathway     102887497 (ADCY1)    04913 Ovarian steroidogenesis     102887497 (ADCY1)    04915 Estrogen signaling pathway     102887497 (ADCY1)    04914 Progesterone-mediated oocyte maturation     102887497 (ADCY1)    04921 Oxytocin signaling pathway     102887497 (ADCY1)    04926 Relaxin signaling pathway     102887497 (ADCY1)    04935 Growth hormone synthesis, secretion and action     102887497 (ADCY1)    04918 Thyroid hormone synthesis     102887497 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     102887497 (ADCY1)    04916 Melanogenesis     102887497 (ADCY1)    04925 Aldosterone synthesis and secretion     102887497 (ADCY1)    04927 Cortisol synthesis and secretion     102887497 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102887497 (ADCY1)    04270 Vascular smooth muscle contraction     102887497 (ADCY1)   09154 Digestive system    04970 Salivary secretion     102887497 (ADCY1)    04971 Gastric acid secretion     102887497 (ADCY1)    04972 Pancreatic secretion     102887497 (ADCY1)    04976 Bile secretion     102887497 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     102887497 (ADCY1)    04727 GABAergic synapse     102887497 (ADCY1)    04725 Cholinergic synapse     102887497 (ADCY1)    04720 Long-term potentiation     102887497 (ADCY1)    04723 Retrograde endocannabinoid signaling     102887497 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102887497 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     102887497 (ADCY1)    04213 Longevity regulating pathway - multiple species     102887497 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     102887497 (ADCY1)    04714 Thermogenesis     102887497 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102887497 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     102887497 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102887497 (ADCY1)    05163 Human cytomegalovirus infection     102887497 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     102887497 (ADCY1)    05142 Chagas disease     102887497 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     102887497 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102887497 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102887497 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102887497 (ADCY1) Enzymes [BR:pale01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102887497 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 DUF6594 Motif Other DBs NCBI-GeneID:  102887497 NCBI-ProteinID:  XP_024902251 LinkDB All DBs Position Unknown AA seq 899 aa AA seqDB search MYGVFVRVLAERSQRRAFLQARNCIEDRAVTPPVSPLQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLTCLNGDYEVEPGHGHERNSF LRTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMRFRTVCYLLVQLMHCRRVFKAEVPFS NVMTCEDDDKRRALRTASEKLRNRSSFSTNAAHAAPGTRVNRYIGRLLEARQTELEMADL HFFTLKYKQAEREHKYHQLRDEHFSSAVVLALVLAALFGLVYLLIIPQSLPVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIRIRTVLCIFIVVLIYAVAQGCVVGCLPWAWSASANG SLVVLSPGGRXXXXXXXXXXXXXHALLCGLVGTLPLTVFLRVSSLPKVILLSVLATSYIL VLELSGYTRAAGGGPVSGGSFEPVVAILLFSCTLALHARQVDIKLRLDYLWAAQAEEERD DMEQVKLDNKRILFNLLPAHVAQHFLTSNPRSMDLYYQSYSQVGVMFASIPNFNDFYIEL DGNNMGVECLRLLNEIIADFDELMEKDFYKDLEKIKTIGSTYMAAVGLVPTTGAKARKCI SAHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVN VASRMDSTGVPGRIQVTEEVHRLLRRRAYRFSCRGKVSVKGKGEMLTYFLEGRTDGNGPQ TRPLSSERRTCLYGRAGLQTGLATGCPRVGAGPGALQGSGLAPQPPGPHLPPAAAGKEA NT seq 2700 nt NT seq  +upstreamnt  +downstreamnt atgtacggcgtcttcgtgagggtcctggccgagcgctcccagcggagagcctttctgcag gcccggaactgcatcgaggaccgggctgtcacaccgcccgtctctcccctccaggagcgg ctgctcatgagtctcctgccccggaatgtcgccatggagatgaaggaagacttcctgaag cccccagagaggattttccacaagatttacatccagcggcatgacaacgtgagcatcctc ttcgcggacatcgtgggcttcacgggcctggcgtcgcagtgcacggcacaggagctggtg aagctgctcaacgagctcttcggcaagtttgacgagctggccacggagaaccactgccgc cgcatcaagatcctgggggactgctactactgcgtgtccggcctcacgcagcccaaggcc gaccacgcccactgctgcgtggagatgggcctggacatgatcgacaccatcacgtccgtg gccgaggccaccgaggtggacctgaacatgcgcgtggggctgcacaccggccgcgtcctc tgcggtgtcctgggcctgcgcaagtggcagtatgacgtgtggtccaacgacgtgactctg gccaacgtcatggaggccgccggcctgcccgggaaggttcacatcacaaagacgacgctg acctgcctgaacggtgactacgaggtggagccgggccacgggcacgagaggaacagtttc ctgaggacacacaacatcgagaccttcttcattgtgccctcgcatcggcggaagatattt ccagggctgatcctgtcggacatcaagccggccaagcggatgaggtttcggacggtgtgc tacctgctggtgcagctcatgcactgccggcgggtgttcaaggccgaggtccccttctcc aacgtcatgacctgcgaggacgacgacaagcgcagggcgttgagaacggcctcagaaaag ctcaggaaccgctcgtccttctccacgaacgccgcgcacgccgccccgggcacccgcgtc aacaggtacatcggccgcctcctggaagcccgccagacggagctggagatggcagacctg cacttcttcaccctgaagtacaagcaggccgagcgggagcacaagtaccaccagctccgg gacgagcacttcagcagcgccgtggtgctcgccctcgtcctggccgccttgttcggcctc gtctacctcctgatcatcccgcagagtctgcctgtcctgctcctgctggtgttctgcatc tgcttcttggtggcttgtgtcctctacctgcacatcacccgggtccagtgcttcccgggc tgcctgaccatccgcatccgcaccgtgctgtgcattttcatcgtggtcctgatctatgcc gtggcccagggatgcgtggtgggctgcctgccctgggcctggagcgccagtgccaacggg tccctggtggtcctgtcgcccggcggccgcgannnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnncgcacgccctgctctgcggcctggtgggcacgctcccgctcaccgtgttcctg cgcgtctcctccttgccgaaggtcatcctgctgtccgtgctcgccacgtcctacatcctg gtcctggagctcagcggctacaccagggccgcggggggcggcccggtctctgggggcagc ttcgagccggtcgtggccatcctgctgttctcgtgcacgctggccctgcacgcccggcag gtggacatcaagctgcggctggactacctgtgggctgcgcaggctgaggaggagcgtgac gacatggagcaggtgaagctggacaacaagaggattctgttcaacctgctgccggcccac gtggcccagcactttctcacgtccaatccccggagcatggacctgtactaccagtcgtac tcgcaggtgggcgtcatgttcgcctccatccccaacttcaacgacttctacatcgagctg gacggcaacaacatgggggtggagtgcctgcgcctcctcaacgagatcatcgctgacttc gacgagctcatggagaaggacttctacaaggacctggagaagatcaagaccatcgggagc acctacatggccgccgtggggctggtgcccacgactggggccaaggctaggaagtgcatc tctgcccacctcagcacgctggcggactttgccatcgagatgtttgacgtcctggacgag atcaactaccagtcgtacaatgactttgtgctccgcgtgggcatcaacgtgggccccgtg gtggccggagtgatcggggctcgccggccacagtacgacatctggggaaacacggtcaac gtggccagtcggatggacagcaccggggttccaggcagaatccaggtgacggaggaggtg caccggctgctgaggcggcgcgcctaccgcttctcgtgccgcggcaaggtcagcgtcaag ggcaagggcgagatgctgacctacttcttggaaggcaggaccgatgggaatggcccccag accaggcccctgagctcggagcggagaacgtgcctgtatgggagagccggcctccagacc ggactggccacaggctgcccccgggtcggagccgggccgggggctctgcagggctcgggg ctcgccccgcagccccccggcccacacctgcctccagcagctgccgggaaggaggcttag

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