Pteropus alecto (black flying fox): 102893368
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Entry
102893368 CDS
T02993
Symbol
DOT1L
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale00310
Lysine degradation
pale01100
Metabolic pathways
pale05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
102893368 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102893368 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pale03036
]
102893368 (DOT1L)
Enzymes [BR:
pale01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
102893368 (DOT1L)
Chromosome and associated proteins [BR:
pale03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102893368 (DOT1L)
HMT complexes
Dot1-containing complex
102893368 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
102893368
NCBI-ProteinID:
XP_024898478
LinkDB
All DBs
Position
Unknown
AA seq
1673 aa
AA seq
DB search
MGHGHEVTSRLTDSDQGFGRRSHGEPPRSGRSAGPVAWLSVEDDPLLSWWLLLVFPILQT
EKQRPGSSVTQPGLWHPSCGAPGQAPAGTARGGGESRGIHSHWPLAHHLLAGKRHGRRPC
PRSACHVGGDPRWHPSATAGRGSSVGRRCSACCLWSPGPAVANLDCSVRSKPCPSVFQDK
HHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLW
KGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMID
EIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWY
GKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSS
KPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSL
KNPKLREEQEAARRRQQRENKSNTTTPTKVPESKVAVTADTPVDSGAEEEKTGTATIKKP
SPSKARKKKLNKKGRKLAGRKRGRPKKMSTANPERKPRKSPTALDLLHAQTVSQAAASPQ
DAYKSPHSPFHQLPPSVQRHPPDQLLLAPTPPALQKLLESFRIQYLQFLAYTKTPQYKAG
LQQLLDQEKEKNARLLGAAQQLFGHCQAQKEEIKRLFQQKLDELGVKALTYDDLIQAQKE
ISAHNQQLREQTEQLETDNRALRGQSLQLLKARCEELRLDWPTLSLEKLLKEKQALKSQI
SEKQRRCLELQISIVELEKSQRQQELLQLKSCVPPDEAVAMHLRGKGGLGRELEVEPSRL
HLELDCSKFSLPPFSSLSPELSVNGHAAGYELCGTLSRPPSKQNTPQDLASVLDQEVVPC
TPSHGSRPRLDKLSGLASPDYTRLSPAKLVLRRHLSQDHAAGSKAATSELHPRAEHVKEN
GLPYHSPGLANGIKLSPQEPRPSSPVALQMTGEKGSEKGLKERGHASSGEAITSLPVSIP
LSTVQPSKLPVSIPLASVVLPSRAEKVRSTPSPVPQARESSSTLEKQVGAHAHGAGSKGL
TLAPTGFSYAGSVAITGALTGSPAPLAPGAEPPAFDESSSSGSLFAPMGSRSSTPQHPPL
LAQPRNSGPASPAHQLCASPRLGATQGPLPDASKGDLPSEAGFSDPESEAKRRAVFTVSA
SAGSAKQSPSSKHSPLPAGTQNHGQDSRKRGRRKRASAGTPSLSTGVSPKRRALPSVAGL
FTQSSGSPLNLNSMVNNINQPLEITAISSPESSLKSSPIPYQDNDQPPVLKKEKPLSQTN
GAHYSPLTSDEEPGSEDEPGSARIERKIATISLESKSPPKTLENGGGLAARKPMPASEPV
NSSKWKATFSPISDLGLAKAVDSPLQAGPALSQNSLFAFRPAPEEPGPADAKLATHPRKS
FPGAVPGAGGLSPSSNPSNGFAFSGGLAADLSLHSFSDGASLPHKAPEAAGLGAPLSFPA
PRGKEGGTEPGPFVNKRQLDGLGGLKGEGGKGREAELGPPTCAPSDKASAHGKAGKGRDR
EPDFKNGHNLFISAAXXXXXXXXXTAASSAGSTAPSAQTHRPFLGTFAPGPQFSLGPMSL
QANLGPSVLQSLFNSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGN
NT seq
5022 nt
NT seq
+upstream
nt +downstream
nt
atgggccacggccacgaggtcacgagccgtctgactgacagtgaccagggcttcggaaga
agaagccatggcgagcccccacgcagtgggcgcagtgctggcccggtggcttggttgtct
gtggaggatgatcctttgctttcctggtggctgttactggtgtttcccattttacagaca
gagaaacagaggcccgggagttctgtaactcagccagggctgtggcatccgagctgcggg
gcgccaggacaggcgccagcgggcactgcgcgtgggggaggggagagtcgaggcatacac
tcccactggccccttgcccaccacctgctggcggggaagcgccacgggcgcagaccctgc
cctaggtcagcatgtcatgtgggcggggatcccagatggcaccccagtgccacagcaggg
cgtgggagctctgtgggccggcgctgcagtgcctgctgcctctggtccccgggccctgcg
gtggccaacctggactgctcggtccgctctaaaccctgtccctctgtttttcaggacaaa
caccacgatgctgctcacgaaatcatcgagaccatcagatgggtctgcgaggaaattccg
gacctcaagctcgccatggagaactacgtcctcattgactacgacaccaaaagctttgaa
agcatgcagaggctttgtgacaagtacaaccgggccatcgacagcattcaccagctgtgg
aagggcaccacgcagcccatgaagctgaacacgcggccgtcgaacggactcctgcggcac
atcctgcagcaggtgtacaaccactcggtgacggaccctgagaagctcaacaactacgag
cccttctccccggaggtgtacggggagacctcctttgacctggtcgcgcagatgatcgac
gagatcaagatgaccgaggacgacctgttcgtggacctgggcagtggagtgggccaggtc
gtgctgcaggtcgccgcggccaccaactgcaaacatcactacggcgtcgagaaagctgat
atcccagccaagtatgcggagaccatggaccgcgagttcaggaagtggatgaaatggtac
ggaaaaaagcatgcagaatacacactggaaagaggcgacttcctctcggaggagtggaga
gagcggatcgccaacacgagtgttatatttgtgaataactttgcctttggtcctgaggtg
gatcaccagctgaaggagcgatttgcaaacatgaaggaaggtggcagaatcgtgtcctcg
aagccctttgcacctctgaacttcagaataaacagtagaaacttgagtgacatcggcacc
atcatgcgcgttgtggagctctctcctctgaagggctcggtgtcatggacggggaagccg
gtgtcctactacctgcataccatcgaccgcactatacttgaaaactatttttctagtctg
aaaaatccaaaactcagggaggaacaagaggcagctcggcgccggcagcaacgagaaaac
aagagcaacacgaccacgcccacgaaagtgcctgagagcaaggtggccgtgaccgcggac
acccccgtggattctggtgctgaggaagaaaaaacagggacggctaccatcaagaagccg
tctccctccaaggcacggaaaaagaagctgaacaagaaggggcggaaactggctggccgg
aagcgcgggcgccccaagaagatgagcactgcgaaccccgagcgtaagcccaggaagagc
ccaactgcactggacctgctgcacgcccagaccgtgtcccaggccgcggcctcgccgcag
gatgcgtacaagtcacctcacagcccatttcatcagctacctcccagcgtgcagcggcac
cctcccgaccagctgctgttggcacccaccccccctgcactgcagaagctgctagagtcc
ttcaggattcagtatctgcagttcctggcatacacgaagaccccccagtacaaggccggc
ctgcagcagctgctggaccaggagaaggagaagaatgcccgcttgctgggtgccgcccag
cagctgttcggccactgccaggcccagaaggaagagatcaagaggctgttccagcagaag
ctggatgagctgggagtgaaggctctgacctacgacgacctgatccaggctcagaaggag
atctccgctcacaatcagcagctgcgggagcagacggagcagctggagacggacaaccgg
gcgctgaggggccagagcctgcagctgctgaaggctcgctgtgaggagctgaggctggac
tggcccacgctgtccctggagaagctgctgaaggagaagcaggccctgaagagccagatc
tcggagaagcagaggcgctgcctggagctgcagatcagcatcgtggagctggagaagagc
cagcggcagcaggagctcctgcagctcaagtcctgcgtgccgcctgacgaggctgtggcc
atgcacctgcgtgggaagggtggcctgggccgagagctggaggtggagcccagtcggctg
cacctggagctggactgctccaagttttcactgcccccgttcagcagcctgagccccgag
ctctccgtgaacggccatgcagccggctacgagctgtgcggcacactgagccggccacca
tccaagcagaacacgccccaggacctggcctccgtgctggaccaggaagtcgtgccctgc
acccccagccacggcagccggccccggctcgacaagctgtcgggcctggcctcgcctgac
tacactcggctctcaccagccaagctggtgctgaggcggcacctgagccaggaccatgcg
gccggcagcaaggcggccaccagtgagctgcatccacgagctgagcacgtcaaggagaac
ggccttccataccacagtccaggcctggctaacggcatcaagctgagccctcaggagcca
cggccctcgtcccccgtggccttgcagatgaccggagagaagggcagcgagaagggtctg
aaggaacgcggccacgccagcagcggggaggccatcaccagcctacccgtcagcatcccg
ctcagcactgtgcagcccagcaagctgcccgtcagcatccctctggccagcgtggtgctg
cccagccgcgccgagaaggtgagaagcacccccagccctgtgccgcaggcccgggagtcc
tcgtccaccctggagaagcaagtgggcgctcatgcccacggcgcggggagcaaaggcctc
accctggcccccacaggcttttcctacgccggctcagtggctatcactggggccctgaca
ggcagtccggctccgctcgctcctggggccgagccccctgcctttgacgagtcctccagc
tcggggagcctcttcgcacccatgggctcccgcagctcgacgccgcaacaccccccactg
ctggcccagccccggaactccggcccagcctcgcctgcccaccagctctgtgccagcccc
cggctcggcgccacccagggcccgctccccgacgccagcaaaggggacctgccctccgag
gccggcttctcggatccagagagcgaggctaaaaggagggctgtcttcaccgtgtcggcc
agtgccggcagcgccaagcagtcaccttccagcaagcacagccctttgcccgcaggcacc
cagaaccacgggcaggacagccgcaagcggggcaggaggaagcgggcgtcagcgggcacg
cccagcctgagtacgggcgtgtcccccaagcgccgggccctgccatccgttgctggcctc
ttcacgcagtcttcagggtcccctctcaacctcaactccatggtcaacaacattaaccag
cccttggaaatcacggccatctcgtcccccgagagctccctgaagagctcccccatccct
taccaggacaatgaccagccgcccgtgctcaagaaggagaagcccctgagccagaccaat
ggggcccactactcccctctgacttcagacgaggagccaggctctgaggatgagccgggc
agcgccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccaaaa
accttggaaaatggcggtggcctggcggcaaggaagcccatgcctgccagcgagccggtc
aacagcagcaagtggaaggccaccttctcgcccatctccgaccttggcctggccaaggcc
gtcgacagcccgctgcaggctggccccgccctgagccagaactccctgtttgctttccgg
cccgccccagaggagcccggcccggccgacgccaagctggccacccaccccaggaagagc
ttccccggggccgtgccgggggccggtgggctgagccccagcagcaacccctccaacggc
ttcgccttcagcggaggcctggccgctgacctcagtttacacagtttcagtgatggtgct
tctctcccccacaaggcccccgaggcggccggcctgggcgcccccttgagcttccctgcc
ccacgaggcaaggagggtggcacggaacccggcccctttgtgaacaagaggcagctggac
ggactgggcggcctgaagggcgagggcggcaagggcagggaggcggagctgggccccccc
acgtgtgcgccctcggacaaggcctcggcacacggcaaggcgggcaagggccgggaccgc
gagcctgacttcaagaacggccacaacctcttcatttccgccgcnnnnnnnnnnnnnnnn
nnnnnnnnnnnnacggcggcgtcctcggcgggcagcacggcgccctccgcccagacgcac
cggcccttcctgggcaccttcgcgcccggcccgcagttttccctgggccccatgtccctg
caagccaacctgggcccgtccgtgctgcagtccttgttcaactccgtgcccgccgccgct
ggcctggtgcacgtctcgtccgccgcgaccagactgaccaactcgcacgccatgggcagc
ttttcctccggggtggcaggcggcgcagttggaggtaactag
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integrated database retrieval system
