Pteropus alecto (black flying fox): 102898998 Help Entry 102898998         CDS       T02993                                  Symbol PTK2 Name (RefSeq) focal adhesion kinase 1   KO K05725   focal adhesion kinase 1 [EC:2.7.10.2] Organism pale  Pteropus alecto (black flying fox) Pathway pale01522   Endocrine resistance pale04012   ErbB signaling pathway pale04062   Chemokine signaling pathway pale04148   Efferocytosis pale04151   PI3K-Akt signaling pathway pale04360   Axon guidance pale04370   VEGF signaling pathway pale04510   Focal adhesion pale04670   Leukocyte transendothelial migration pale04810   Regulation of actin cytoskeleton pale04935   Growth hormone synthesis, secretion and action pale05100   Bacterial invasion of epithelial cells pale05135   Yersinia infection pale05146   Amoebiasis pale05163   Human cytomegalovirus infection pale05165   Human papillomavirus infection pale05170   Human immunodeficiency virus 1 infection pale05200   Pathways in cancer pale05202   Transcriptional misregulation in cancer pale05205   Proteoglycans in cancer pale05208   Chemical carcinogenesis - reactive oxygen species pale05222   Small cell lung cancer pale05417   Lipid and atherosclerosis pale05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:pale00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102898998 (PTK2)    04370 VEGF signaling pathway     102898998 (PTK2)    04151 PI3K-Akt signaling pathway     102898998 (PTK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     102898998 (PTK2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     102898998 (PTK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102898998 (PTK2)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     102898998 (PTK2)    04062 Chemokine signaling pathway     102898998 (PTK2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     102898998 (PTK2)   09158 Development and regeneration    04360 Axon guidance     102898998 (PTK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102898998 (PTK2)    05202 Transcriptional misregulation in cancer     102898998 (PTK2)    05205 Proteoglycans in cancer     102898998 (PTK2)    05208 Chemical carcinogenesis - reactive oxygen species     102898998 (PTK2)   09162 Cancer: specific types    05222 Small cell lung cancer     102898998 (PTK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102898998 (PTK2)    05163 Human cytomegalovirus infection     102898998 (PTK2)    05165 Human papillomavirus infection     102898998 (PTK2)   09171 Infectious disease: bacterial    05135 Yersinia infection     102898998 (PTK2)    05100 Bacterial invasion of epithelial cells     102898998 (PTK2)   09174 Infectious disease: parasitic    05146 Amoebiasis     102898998 (PTK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102898998 (PTK2)    05418 Fluid shear stress and atherosclerosis     102898998 (PTK2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102898998 (PTK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pale01001]     102898998 (PTK2)    01009 Protein phosphatases and associated proteins [BR:pale01009]     102898998 (PTK2) Enzymes [BR:pale01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102898998 (PTK2) Protein kinases [BR:pale01001]  Non-receptor tyrosine kinases   FAK family    102898998 (PTK2) Protein phosphatases and associated proteins [BR:pale01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102898998 (PTK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_C_FAK1 FERM_N_2 FERM_M Kinase-like FERM_F2 Haspin_kinase GIT1_C Motif Other DBs NCBI-GeneID:  102898998 NCBI-ProteinID:  XP_024903358 LinkDB All DBs Position Unknown AA seq 1089 aa AA seqDB search MAAAYLDPNLNHTPNSSAKTHLGTGVERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEW KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMSEVADQVDQDIALKLGCLEIRRSY WEMRGNALEKKSNYEVLEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESI LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCSPTHLADFNQVQ TIQYSNSDDKDRKGMLQLKVAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFII RPQKEGERALPSIPKLANSDKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE RIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKHSLGLASLVLYAYQLGTALAYLESK RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA YDPSRRPRFTDSACWTRLLTGQTIREEFRPAGGSPEPRDMWGGRRPPAERRTILEEEKAQ QEERMRMESRRQVAVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSG YPVPHGVTAMASSIYPGQAALLDQADPWNHRPQETATWQPTAEESAALDLRGLGQVLPPH LMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGGLQGLTGNQHIYQPVGK PDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANLDRSNDR VYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPVLPASTHREI EMAQKLLNSDLGEVISKTKLAQQCVVTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARL KPRGQTRPH NT seq 3270 nt NT seq  +upstreamnt  +downstreamnt atggcagctgcttacctcgacccgaacttgaatcacacaccgaattcgagtgccaagact cacctgggtacaggtgtggaacgctcccctggagcgatggagcgcgtgctcaaggtcttt cattattttgagagcaacagcgagccaaccacctgggccagtatcatcaggcatggggac gctaccgacgtcaggggcatcattcagaagatagtggacagtcacaaagtaaagcacgtg gcctgctatggatttcgcctcagtcacctgcggtccgaggaggttcactggctccatttg gatatgggtgtctccaacgtgagggagaagtatgaacttgcacacccaccagaggagtgg aaatatgaattgagaattcgttatttgccaaaaggatttctaaaccagttcactgaagac aagccaactttgaatttcttctatcaacaggtgaagagcgattacatgtcagaggtagcc gaccaggtggatcaggacattgctctgaagctgggctgtctagaaatacggcggtcatac tgggagatgcggggcaatgcgctggagaagaagtctaactatgaagttttagaaaaggat gtcggcttgaagcgatttttccctaggagtttactggattctgtcaaggccaaaacactc agaaaactgatccaacagacgttcagacagttcgccaacctgaacagagaagaaagcatt ctgaagttcttcgagatcctgtccccagtgtacagattcgataaagaatgcttcaagtgc gccctcggttcgagctggatcatttcggtggagctggcgatcggcccggaggaaggcatc agctacctcacggacaagggctgcagccccacacacctggccgacttcaatcaagtgcag accatccagtattcaaacagcgacgacaaggacaggaaaggaatgctccagctgaaagtc gcaggcgcgcccgagcctctgacagtgacagcgccatccctaaccatcgctgagaatatg gctgacttgatagatggatactgccggctggtgaatggagccacgcagtcttttatcatc agaccccagaaagaaggcgaacgggctttgccatcgataccaaagctggccaacagtgac aagcagggcgtgcggacacatgcggtctccgtgtcagaaacagacgattatgcggagatt atagatgaagaagatacttacactatgccctcaaccagggactatgagattcaaagagag aggatagagctcggccgctgcatcggggaaggccagttcggagacgtgcaccagggcgtt tacatgagcccggagaatccagctttggcggttgcaattaaaacatgtaaaaactgtact tcggacagcgtgagagagaaattccttcaagaagccttgacgatgcgccagttcgaccac cctcacatcgtgaagctgatcggagtcatcacggagaaccccgtctggatcatcatggag ctgtgcacactcggagagctgcggtcgttcctgcaggtcaggaagcacagcctgggcctg gcgtcgctggtgctgtacgcctaccagctgggcacggccctcgcctacctggaaagcaaa cgattcgtgcacagggacattgctgctcggaatgttctggtgtcctcaaatgattgtgtg aaattaggagactttggattgtcccgctatatggaagacagtacctactacaaagcttcc aaaggaaaattgcctattaaatggatggctccagagtcaatcaattttcgacgttttacc tcagctagtgatgtgtggatgtttggcgtgtgcatgtgggagatcctgatgcacggcgtg aagcctttccagggcgtgaagaacaacgacgtgatcggccggatcgagaacggggaacgg ctgccgatgcctccaaactgccctccgacgctctacagcctcatgacgaagtgctgggcc tacgaccccagcaggcggccccggttcaccgactcggcctgctggacaaggctcctgacc gggcagacgatccgggaagaattcaggccggccggcggcagccccgagccgcgggacatg tggggcggcaggcggcccccggcggagcggcgcacgatcctggaggaggagaaggctcag caagaggagcggatgcggatggagtcccgcagacaggtcgcggtgtcctgggactccgga ggatccgacgaggcaccgcccaagcccagcagacccggttatcctagtccaaggtccagt gaaggattttatcccagcccacagcacatggtacaaaccaaccattaccaggtctctggc taccccgttccacatggggtaacagccatggccagcagcatctacccggggcaggcagct ctcttggaccaggcggacccgtggaatcacaggccgcaggagacggcgacgtggcagccc accgcggaggagtctgcagcactggacctgcggggcctcggccaggtgctgccgccacac ctgatggaggagcggctgatccggcagcagcaggagatggaggaggaccagcgctggctg gagaaggaggagcgctttctgaagcctgacgtgcggctctcacgaggcagcatcgacagg gaggacggagggctccagggcctgactggaaaccagcacatctaccagcccgtggggaag ccagatcctgcagctccgccaaagaagccaccacgccctggagcccctggccacctgggc agcctcgccagcctcagcagccctggggacagttacaacgagggcgtcaagccgtggagg cttcagccccaggaaatcagcccccctcccactgccaacctggaccgctccaacgacagg gtatacgagaacgtgacgggcctggtgaaggccgtcatcgagatgtccagcaagatccag ccagccccgccagaggagtacgtgcccatggtgaaggaggtcggcctggccctgcggacg ctgctggccacggtggatgagaccattcccgtcctgccggccagcacccaccgagagatc gagatggcccagaagctgctgaactccgacctgggggaggtcatcagcaagacgaagctg gcccagcagtgcgtcgtgaccagcctccagcaggagtacaagaagcagatgctgaccgcc gcccacgcactggccgtcgacgccaagaacctgctggacgtcatcgaccaggccaggctg aagccgcgcggacagacgaggccgcactga

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