KEGG   PATHWAY: hsa00430
Entry
hsa00430                    Pathway                                
Name
Taurine and hypotaurine metabolism - Homo sapiens (human)
Class
Metabolism; Metabolism of other amino acids
Pathway map
hsa00430  Taurine and hypotaurine metabolism
hsa00430

Drug
D02755  Acivicin (USAN/INN)
Other DBs
GO: 0019530
Organism
Homo sapiens (human) [GN:hsa]
Gene
1036  CDO1; cysteine dioxygenase type 1 [KO:K00456] [EC:1.13.11.20]
2571  GAD1; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
2572  GAD2; glutamate decarboxylase 2 [KO:K01580] [EC:4.1.1.15]
339896  GADL1; glutamate decarboxylase like 1 [KO:K18966] [EC:4.1.1.29 4.1.1.11]
51380  CSAD; cysteine sulfinic acid decarboxylase [KO:K18966] [EC:4.1.1.29 4.1.1.11]
84890  ADO; 2-aminoethanethiol dioxygenase [KO:K10712] [EC:1.13.11.19]
2326  FMO1; flavin containing dimethylaniline monoxygenase 1 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
2327  FMO2; flavin containing dimethylaniline monoxygenase 2 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
2330  FMO5; flavin containing dimethylaniline monoxygenase 5 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
2328  FMO3; flavin containing dimethylaniline monoxygenase 3 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
2329  FMO4; flavin containing dimethylaniline monoxygenase 4 [KO:K00485] [EC:1.14.13.8 1.8.1.-]
2686  GGT7; gamma-glutamyltransferase 7 [KO:K00681] [EC:2.3.2.2 3.4.19.13]
124975  GGT6; gamma-glutamyltransferase 6 [KO:K00681] [EC:2.3.2.2 3.4.19.13]
2678  GGT1; gamma-glutamyltransferase 1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
2687  GGT5; gamma-glutamyltransferase 5 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
570  BAAT; bile acid-CoA:amino acid N-acyltransferase [KO:K00659] [EC:2.3.1.65 3.1.2.2]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00033  Acetate
C00041  L-Alanine
C00084  Acetaldehyde
C00094  Sulfite
C00097  L-Cysteine
C00227  Acetyl phosphate
C00245  Taurine
C00506  L-Cysteate
C00519  Hypotaurine
C00593  Sulfoacetaldehyde
C00606  3-Sulfino-L-alanine
C01678  Cysteamine
C01959  Taurocyamine
C03149  N-Phosphotaurocyamine
C05122  Taurocholate
C05123  2-Hydroxyethanesulfonate
C05844  5-L-Glutamyl-taurine
C06735  Aminoacetaldehyde
C14179  Sulfoacetate
C19685  Sulfoacetyl-CoA
Reference
  Authors
Cook AM, Denger K.
  Title
Dissimilation of the C2 sulfonates.
  Journal
Arch Microbiol 179:1-6 (2002)
DOI:10.1007/s00203-002-0497-0
Reference
  Authors
Laue H, Cook AM.
  Title
Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia.
  Journal
Eur J Biochem 267:6841-8 (2000)
DOI:10.1046/j.1432-1033.2000.01782.x
Reference
  Authors
Ruff J, Denger K, Cook AM.
  Title
Sulphoacetaldehyde acetyltransferase yields acetyl phosphate: purification from Alcaligenes defragrans and gene clusters in taurine degradation.
  Journal
Biochem J 369:275-85 (2003)
DOI:10.1042/BJ20021455
Reference
  Authors
Bruggemann C, Denger K, Cook AM, Ruff J.
  Title
Enzymes and genes of taurine and isethionate dissimilation in Paracoccus denitrificans.
  Journal
Microbiology 150:805-16 (2004)
DOI:10.1099/mic.0.26795-0
Reference
  Authors
Denger K, Weinitschke S, Hollemeyer K, Cook AM.
  Title
Sulfoacetate generated by Rhodopseudomonas palustris from taurine.
  Journal
Arch Microbiol 182:254-8 (2004)
DOI:10.1007/s00203-004-0678-0
Reference
  Authors
Denger K, Ruff J, Schleheck D, Cook AM.
  Title
Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source.
  Journal
Microbiology 150:1859-67 (2004)
DOI:10.1099/mic.0.27077-0
Reference
  Authors
Styp von Rekowski K, Denger K, Cook AM.
  Title
Isethionate as a product from taurine during nitrogen-limited growth of Klebsiella oxytoca TauN1.
  Journal
Arch Microbiol 183:325-30 (2005)
DOI:10.1007/s00203-005-0776-7
Reference
PMID:4297098
  Authors
Jacobsen JG, Smith LH
  Title
Biochemistry and physiology of taurine and taurine derivatives.
  Journal
Physiol Rev 48:424-511 (1968)
DOI:10.1152/physrev.1968.48.2.424
Related
pathway
hsa00270  Cysteine and methionine metabolism
hsa00480  Glutathione metabolism
hsa00620  Pyruvate metabolism
hsa00920  Sulfur metabolism
KO pathway
ko00430   
LinkDB

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