KEGG   PATHWAY: ctln01210
Entry
ctln01210                   Pathway                                
Name
2-Oxocarboxylic acid metabolism - Chlamydia trachomatis L2b/Canada2
Description
2-Oxocarboxylic acids, also called 2-oxo acids and alpha-keto acids, are the most elementary set of metabolites that includes pyruvate (2-oxopropanoate), 2-oxobutanoate, oxaloacetate (2-oxosuccinate) and 2-oxoglutarate. This diagram illustrates the architecture of chain extension and modification reaction modules for 2-oxocarboxylic acids. The chain extension module RM001 is a tricarboxylic pathway where acetyl-CoA derived carbon is used to extend the chain length by one. The chain modification modules RM002 (including RM032) and RM033, together with a reductive amination step (RC00006 or RC00036), generate basic and branched-chain amino acids, respectively. The modification module RM030 is used in the biosynthesis of glucosinolates, a class of plant secondary metabolites, for conversion to oxime followed by addition of thio-glucose moiety. Furthermore, the chain extension from 2-oxoadipate to 2-oxosuberate is followed by coenzyme B biosynthesis in methonogenic archaea.
Class
Pathway map
ctln01210  2-Oxocarboxylic acid metabolism
ctln01210

Module
ctln_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:ctln01210]
ctln_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ctln01210]
Organism
Chlamydia trachomatis L2b/Canada2 [GN:ctln]
Related
pathway
ctln00020  Citrate cycle (TCA cycle)
ctln00250  Alanine, aspartate and glutamate metabolism
ctln00260  Glycine, serine and threonine metabolism
ctln00270  Cysteine and methionine metabolism
ctln00290  Valine, leucine and isoleucine biosynthesis
ctln00300  Lysine biosynthesis
ctln00310  Lysine degradation
ctln00620  Pyruvate metabolism
ctln00640  Propanoate metabolism
ctln00680  Methane metabolism
KO pathway
ko01210   
LinkDB

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