KEGG   PATHWAY: ec00232
Entry
ec00232                     Pathway                                
Name
Caffeine metabolism
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
ec00232  Caffeine metabolism
ec00232

Module
M00915  Caffeine degradation, caffeine => xanthine [PATH:ec00232]
Other DBs
UMBBD: caf caf2
Enzyme
1.14.13.128   
1.14.13.178   
1.14.13.179   
1.14.13.212   
1.14.14.1   
1.17.3.2   
1.17.5.2   
1.7.3.3   
2.1.1.158   
2.1.1.159   
2.1.1.160   
2.3.1.5   
3.2.2.25   
Compound
C00048  Glyoxylate
C00385  Xanthine
C01762  Xanthosine
C07130  Theophylline
C07480  Theobromine
C07481  Caffeine
C13747  1,7-Dimethylxanthine
C16352  7-Methylxanthosine
C16353  7-Methylxanthine
C16355  7-Methyluric acid
C16356  1,7-Dimethyluric acid
C16357  3-Methylxanthine
C16358  1-Methylxanthine
C16359  1-Methyluric acid
C16360  3,7-Dimethyluric acid
C16361  1,3,7-Trimethyluric acid
C16362  3,6,8-Trimethylallantoin
C16363  N-Methylurea
C16364  N,N'-Dimethylurea
C16365  5-Acetylamino-6-formylamino-3-methyluracil
C16366  5-Acetylamino-6-amino-3-methyluracil
C21144  1,3,7-Trimethyl-5-hydroxyisourate
Reference
PMID:9705852
  Authors
Madyastha KM, Sridhar GR.
  Title
A novel pathway for the metabolism of caffeine by a mixed culture consortium.
  Journal
Biochem Biophys Res Commun 249:178-81 (1998)
DOI:10.1006/bbrc.1998.9102
Reference
PMID:14977550
  Authors
Mazzafera P.
  Title
Catabolism of caffeine in plants and microorganisms.
  Journal
Front Biosci 9:1348-59 (2004)
DOI:10.2741/1339
Reference
PMID:11393735
  Authors
Nyeki A, Biollaz J, Kesselring UW, Decosterd LA.
  Title
Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.
  Journal
J Chromatogr B Biomed Sci Appl 755:73-84 (2001)
DOI:10.1016/S0378-4347(00)00616-2
Reference
PMID:11544129
  Authors
Ashihara H, Crozier A.
  Title
Caffeine: a well known but little mentioned compound in plant science.
  Journal
Trends Plant Sci 6:407-13 (2001)
DOI:10.1016/S1360-1385(01)02055-6
Reference
PMID:16333668
  Authors
Yoneyama N, Morimoto H, Ye CX, Ashihara H, Mizuno K, Kato M.
  Title
Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme.
  Journal
Mol Genet Genomics 275:125-35 (2006)
DOI:10.1007/s00438-005-0070-z
Related
pathway
ec00230  Purine metabolism
ec00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00232   
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