KEGG PATHWAY: ec00750

PATHWAY: ec00750

Entry

ec00750                     Pathway

Name

Vitamin B6 metabolism

Class

Metabolism; Metabolism of cofactors and vitamins

Pathway map

ec00750

Vitamin B6 metabolism

Module

M00124

Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:ec00750]

M00916

Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:ec00750]

Other DBs

GO:

0042816

Enzyme

1.1.1.107

1.1.1.262

1.1.1.290

1.1.1.416

1.1.1.65

1.1.3.12

1.1.99.42

1.1.99.9

1.14.13.241

1.14.13.242

1.2.1.100

1.2.1.102

1.2.1.72

1.2.3.1

1.2.3.8

1.4.3.5

2.6.1.30

2.6.1.31

2.6.1.52

2.6.1.54

2.6.99.2

2.7.1.35

3.1.1.27

3.1.3.74

3.5.1.29

3.5.1.66

4.1.1.51

4.2.3.1

4.3.3.6

Compound

C00018

Pyridoxal phosphate

C00064

L-Glutamine

C00117

D-Ribose 5-phosphate

C00118

D-Glyceraldehyde 3-phosphate

C00232

Succinate semialdehyde

C00250

Pyridoxal

C00266

Glycolaldehyde

C00279

D-Erythrose 4-phosphate

C00314

Pyridoxine

C00534

Pyridoxamine

C00627

Pyridoxine phosphate

C00647

Pyridoxamine phosphate

C00847

4-Pyridoxate

C00971

4-Pyridoxolactone

C01215

2-(Acetamidomethylene)succinate

C01270

3-Hydroxy-2-methylpyridine-5-carboxylate

C03393

4-Phospho-D-erythronate

C04106

2-(Hydroxymethyl)-4-oxobutanoate

C04604

3-Hydroxy-2-methylpyridine-4,5-dicarboxylate

C04690

2-(Hydroxymethyl)-3-(acetamidomethylene)succinate

C04773

3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate

C06050

2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate

C06051

Isopyridoxal

C06052

5-Pyridoxolactone

C06054

2-Oxo-3-hydroxy-4-phosphobutanoate

C06055

O-Phospho-4-hydroxy-L-threonine

C06056

4-Hydroxy-L-threonine

C07335

2-Amino-3-oxo-4-phosphonooxybutyrate

C11638

3-Amino-2-oxopropyl phosphate

Reference

PMID:10753941

Authors

Tazoe M, Ichikawa K, Hoshino T.

Title

Biosynthesis of vitamin B(6) in rhizobium.

Journal

J Biol Chem 275:11300-5 (2000)
DOI:10.1074/jbc.275.15.11300

Reference

PMID:9696782

Authors

Yang Y, Zhao G, Man TK, Winkler ME.

Title

Involvement of the gapA- and epd (gapB)-encoded dehydrogenases in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12.

Journal

J Bacteriol 180:4294-9 (1998)
DOI:10.1128/JB.180.16.4294-4299.1998

Reference

PMID:12269807

Authors

Yeh JI, Du S, Pohl E, Cane DE.

Title

Multistate binding in pyridoxine 5'-phosphate synthase: 1.96 A crystal structure in complex with 1-deoxy-D-xylulose phosphate.

Journal

Biochemistry 41:11649-57 (2002)
DOI:10.1021/bi026292t

Reference

PMID:10225425

Authors

Laber B, Maurer W, Scharf S, Stepusin K, Schmidt FS.

Title

Vitamin B6 biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5-phosphate by PdxA and PdxJ protein.

Journal

FEBS Lett 449:45-8 (1999)
DOI:10.1016/S0014-5793(99)00393-2

Reference

PMID:16157873

Authors

Tambasco-Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick TB.

Title

Vitamin B6 biosynthesis in higher plants.

Journal

Proc Natl Acad Sci U S A 102:13687-92 (2005)
DOI:10.1073/pnas.0506228102

Reference

PMID:22276911

Authors

Nagase T, Mugo AN, Chu HN, Yoshikane Y, Ohnishi K, Yagi T

Title

The mll6786 gene encodes a repressor protein controlling the degradation pathway for vitamin B6 in Mesorhizobium loti.

Journal

FEMS Microbiol Lett 329:116-22 (2012)
DOI:10.1111/j.1574-6968.2012.02510.x

Related
pathway

ec00010

Glycolysis / Gluconeogenesis

ec00030

Pentose phosphate pathway

ec00630

Glyoxylate and dicarboxylate metabolism

ec00650

Butanoate metabolism

ec00730

Thiamine metabolism

KO pathway

ko00750

LinkDB

DBGET integrated database retrieval system