KEGG   PATHWAY: eco00330
Entry
eco00330                    Pathway                                
Name
Arginine and proline metabolism - Escherichia coli K-12 MG1655
Class
Metabolism; Amino acid metabolism
Pathway map
eco00330  Arginine and proline metabolism
eco00330

Module
eco_M00015  Proline biosynthesis, glutamate => proline [PATH:eco00330]
eco_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:eco00330]
eco_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:eco00330]
eco_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:eco00330]
eco_M00970  Proline degradation, proline => glutamate [PATH:eco00330]
Other DBs
GO: 0006525 0006560
Organism
Escherichia coli K-12 MG1655 [GN:eco]
Gene
b0337  codA; cytosine/isoguanine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
b4117  adiA; arginine decarboxylase, degradative [KO:K01584] [EC:4.1.1.19]
b2938  speA; arginine decarboxylase, biosynthetic [KO:K01585] [EC:4.1.1.19]
b2937  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
b0693  speF; inducible ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
b2965  speC; constitutive ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
b0121  speE; spermidine synthase [KO:K00797] [EC:2.5.1.16]
b0120  speD; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
b3073  patA; putrescine aminotransferase [KO:K09251] [EC:2.6.1.82]
b1444  patD; gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
b1584  speG; spermidine N-acetyltransferase [KO:K00657] [EC:2.3.1.57]
b1747  astA; arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
b1745  astB; N-succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
b1748  astC; succinylornithine transaminase [KO:K00840] [EC:2.6.1.81]
b1746  astD; aldehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
b1744  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
b1297  puuA; glutamate-putrescine ligase [KO:K09470] [EC:6.3.1.11]
b1301  puuB; gamma-glutamylputrescine oxidase [KO:K09471] [EC:1.4.3.-]
b1300  puuC; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
b1298  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
b0386  proC; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
b1014  putA; fused DNA-binding transcriptional repressor/proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase PutA [KO:K13821] [EC:1.5.5.2 1.2.1.88]
b0242  proB; glutamate 5-kinase [KO:K00931] [EC:2.7.2.11]
b0243  proA; glutamate-5-semialdehyde dehydrogenase [KO:K00147] [EC:1.2.1.41]
b0928  aspC; aspartate aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
eco00020  Citrate cycle (TCA cycle)
eco00220  Arginine biosynthesis
eco00250  Alanine, aspartate and glutamate metabolism
eco00260  Glycine, serine and threonine metabolism
eco00270  Cysteine and methionine metabolism
eco00310  Lysine degradation
eco00410  beta-Alanine metabolism
eco00470  D-Amino acid metabolism
eco00480  Glutathione metabolism
eco00630  Glyoxylate and dicarboxylate metabolism
eco00650  Butanoate metabolism
eco00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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