KEGG   PATHWAY: mtl00230
Entry
mtl00230                    Pathway                                
Name
Purine metabolism - Mycobacterium tuberculosis CCDC5180
Class
Metabolism; Nucleotide metabolism
Pathway map
mtl00230  Purine metabolism
mtl00230

Module
mtl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mtl00230]
mtl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mtl00230]
mtl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mtl00230]
mtl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mtl00230]
Other DBs
GO: 0006163 0042278
Organism
Mycobacterium tuberculosis CCDC5180 [GN:mtl]
Gene
CCDC5180_2789  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CCDC5180_0932  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CCDC5180_0739  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CCDC5180_0706  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CCDC5180_0873  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CCDC5180_0359  phosphoribosylglycinamide formyltransferase 2 purT [KO:K08289] [EC:6.3.1.21]
CCDC5180_0735  phosphoribosylformylglycinamidine synthase II purL [KO:K23269] [EC:6.3.5.3]
CCDC5180_0721  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
CCDC5180_0740  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
CCDC5180_2986  phosphoribosylaminoimidazole carboxylase ATPase subunit purK [KO:K01589] [EC:6.3.4.18]
CCDC5180_2985  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
CCDC5180_0714  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CCDC5180_0711  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CCDC5180_0874  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CCDC5180_2353  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CCDC5180_3016  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
CCDC5180_1960  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CCDC5180_3091  nucleoside hydrolase IunH [KO:K01239] [EC:3.2.2.1]
CCDC5180_3311  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CCDC5180_3108  inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CCDC5180_3109  inositol-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CCDC5180_2228  nucleoside diphosphate kinase ndkA [KO:K00940] [EC:2.7.4.6]
CCDC5180_1233  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CCDC5180_3095  GMP synthase [KO:K01951] [EC:6.3.5.2]
CCDC5180_1679  inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
CCDC5180_1278  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CCDC5180_2773  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CCDC5180_0527  ribonucleoside-diphosphate reductase large subunit NrdZ [KO:K00525] [EC:1.17.4.1]
CCDC5180_2770  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CCDC5180_0216  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CCDC5180_1805  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CCDC5180_2140  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
CCDC5180_2352  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CCDC5180_0459  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CCDC5180_0941  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CCDC5180_1160  Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CCDC5180_1490  adenylate cyclase, putative [KO:K01768] [EC:4.6.1.1]
CCDC5180_3330  transmembrane protein [KO:K01768] [EC:4.6.1.1]
CCDC5180_0330  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CCDC5180_2010  cbhK, carbohydrate kinase CbhK [KO:K00856] [EC:2.7.1.20]
CCDC5180_3023  adenosine deaminase add [KO:K01488] [EC:3.5.4.4]
CCDC5180_0670  adk, adenylate kinase [KO:K00939] [EC:2.7.4.3]
CCDC5180_0936  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
CCDC5180_2381  hypothetical protein [KO:K19710] [EC:2.7.7.53]
CCDC5180_1181  bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein [KO:K00955] [EC:2.7.7.4 2.7.1.25]
CCDC5180_1180  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
CCDC5180_1685  ureC, urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CCDC5180_1684  ureB, urease subunit beta [KO:K01429] [EC:3.5.1.5]
CCDC5180_1683  ureA, urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mtl00030  Pentose phosphate pathway
mtl00220  Arginine biosynthesis
mtl00250  Alanine, aspartate and glutamate metabolism
mtl00260  Glycine, serine and threonine metabolism
mtl00340  Histidine metabolism
mtl00630  Glyoxylate and dicarboxylate metabolism
mtl00730  Thiamine metabolism
mtl00740  Riboflavin metabolism
mtl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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