KEGG   PATHWAY: sce00630
Entry
sce00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Saccharomyces cerevisiae (budding yeast)
Class
Metabolism; Carbohydrate metabolism
Pathway map
sce00630  Glyoxylate and dicarboxylate metabolism
sce00630

Module
sce_M00012  Glyoxylate cycle [PATH:sce00630]
sce_M00621  Glycine cleavage system [PATH:sce00630]
Other DBs
GO: 0046487 0043648
Organism
Saccharomyces cerevisiae (budding yeast) [GN:sce]
Gene
YPR006C  ICL2; methylisocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1]
YER065C  ICL1; isocitrate lyase 1 [KO:K01637] [EC:4.1.3.1]
YAL054C  ACS1; acetate--CoA ligase 1 [KO:K01895] [EC:6.2.1.1]
YLR153C  ACS2; acetate--CoA ligase ACS2 [KO:K01895] [EC:6.2.1.1]
YIR031C  DAL7; malate synthase DAL7 [KO:K01638] [EC:2.3.3.9]
YNL117W  MLS1; malate synthase MLS1 [KO:K01638] [EC:2.3.3.9]
YKL085W  MDH1; malate dehydrogenase MDH1 [KO:K00026] [EC:1.1.1.37]
YOL126C  MDH2; malate dehydrogenase MDH2 [KO:K00026] [EC:1.1.1.37]
YDL078C  MDH3; malate dehydrogenase MDH3 [KO:K00026] [EC:1.1.1.37]
YCR005C  CIT2; citrate (Si)-synthase CIT2 [KO:K01647] [EC:2.3.3.1]
YNR001C  CIT1; citrate (Si)-synthase CIT1 [KO:K01647] [EC:2.3.3.1]
YPR001W  CIT3; citrate (Si)-synthase CIT3 [KO:K01647] [EC:2.3.3.1]
YLR304C  ACO1; aconitate hydratase ACO1 [KO:K01681] [EC:4.2.1.3]
YPL028W  ERG10; acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
YDR256C  CTA1; catalase A [KO:K03781] [EC:1.11.1.6]
YGR088W  CTT1; catalase T [KO:K03781] [EC:1.11.1.6]
YNL274C  GOR1; glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
YFL030W  AGX1; alanine--glyoxylate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
YPR035W  GLN1; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
YBR263W  SHM1; glycine hydroxymethyltransferase SHM1 [KO:K00600] [EC:2.1.2.1]
YLR058C  SHM2; glycine hydroxymethyltransferase SHM2 [KO:K00600] [EC:2.1.2.1]
YMR189W  GCV2; glycine decarboxylase subunit P [KO:K00281] [EC:1.4.4.2]
YDR019C  GCV1; glycine decarboxylase subunit T [KO:K00605] [EC:2.1.2.10]
YFL018C  LPD1; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
YAL044C  GCV3; glycine decarboxylase subunit H [KO:K02437]
YGR205W  TDA10; putative ATP-dependent kinase [KO:K15918] [EC:2.7.1.31]
YOR388C  FDH1; formate dehydrogenase (NAD+) [KO:K00122] [EC:1.17.1.9]
YDR428C  BNA7; arylformamidase [KO:K14263] [EC:3.5.1.9]
YBR222C  PCS60; Pcs60p [KO:K22133] [EC:6.2.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sce00010  Glycolysis / Gluconeogenesis
sce00020  Citrate cycle (TCA cycle)
sce00030  Pentose phosphate pathway
sce00053  Ascorbate and aldarate metabolism
sce00071  Fatty acid degradation
sce00230  Purine metabolism
sce00250  Alanine, aspartate and glutamate metabolism
sce00260  Glycine, serine and threonine metabolism
sce00620  Pyruvate metabolism
sce00750  Vitamin B6 metabolism
sce00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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