KEGG   PATHWAY: wex00010
Entry
wex00010                    Pathway                                
Name
Glycolysis / Gluconeogenesis - Wolbachia endosymbiont of Ostrinia furnacalis
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
wex00010  Glycolysis / Gluconeogenesis
wex00010

Module
wex_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:wex00010]
Other DBs
GO: 0006096 0006094
Organism
Wolbachia endosymbiont of Ostrinia furnacalis [GN:wex]
Gene
M1L25_000490  glpX; class II fructose-bisphosphatase [KO:K02446] [EC:3.1.3.11]
M1L25_000258  class I fructose-bisphosphate aldolase [KO:K11645] [EC:4.1.2.13]
M1L25_000988  triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
M1L25_000626  gap; type I glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
M1L25_000007  phosphoglycerate kinase [KO:K00927] [EC:2.7.2.3]
M1L25_000967  gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [KO:K15633] [EC:5.4.2.12]
M1L25_000573  eno; phosphopyruvate hydratase [KO:K01689] [EC:4.2.1.11]
M1L25_000371  ppdK; pyruvate, phosphate dikinase [KO:K01006] [EC:2.7.9.1]
M1L25_000505  pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha [KO:K00161] [EC:1.2.4.1]
M1L25_000699  pyruvate dehydrogenase complex E1 component subunit beta [KO:K00162] [EC:1.2.4.1]
M1L25_001111  pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase [KO:K00627] [EC:2.3.1.12]
M1L25_000229  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
M1L25_000508  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
wex00020  Citrate cycle (TCA cycle)
wex00030  Pentose phosphate pathway
wex00620  Pyruvate metabolism
wex00640  Propanoate metabolism
wex00710  Carbon fixation in photosynthetic organisms
KO pathway
ko00010   
LinkDB

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