Prionailurus bengalensis (leopard cat): 122478409
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Entry
122478409 CDS
T07574
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00010
Glycolysis / Gluconeogenesis
pbg00020
Citrate cycle (TCA cycle)
pbg00620
Pyruvate metabolism
pbg00785
Lipoic acid metabolism
pbg01100
Metabolic pathways
pbg01200
Carbon metabolism
pbg01210
2-Oxocarboxylic acid metabolism
pbg04066
HIF-1 signaling pathway
pbg04922
Glucagon signaling pathway
pbg05230
Central carbon metabolism in cancer
pbg05415
Diabetic cardiomyopathy
Module
pbg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122478409 (PDHA2)
00020 Citrate cycle (TCA cycle)
122478409 (PDHA2)
00620 Pyruvate metabolism
122478409 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122478409 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122478409 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122478409 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122478409 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122478409 (PDHA2)
Enzymes [BR:
pbg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
122478409 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Chal_sti_synt_N
Motif
Other DBs
NCBI-GeneID:
122478409
NCBI-ProteinID:
XP_043427975
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Position
B1:complement(126076836..126078205)
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AA seq
391 aa
AA seq
DB search
MRKMLAATVSRVLSGVTQKPASRVLVASCNYSNDAMFAIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACSVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNKEVCLALYGDGAANQGQIAEAHNMAALWKLPCVFICENNLYGMGTPVERASAS
TDYYKRGNFIPGLRVDGMDVLGVREATKFVADYCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRTREEVQNVRRESDPIMLLKDRMVNSKLATVEELKDIDVEVRKEVEDAAQFAMTDPEP
PLEELAHHIYCNTPAFEVRGANQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgccactgtctcccgcgtgttgtccggggtcacgcagaagccc
gctagcagagtgctggtggcatcctgtaactattcaaatgatgcgatgtttgcaattaag
aaatgtgatctttatcgcttagaagagggtcctcctgtcacaacagtgctcacccgggag
gatgggctcaaatactacaggatgatgcagactgttcgccgaatggagctgaaggcagat
cagctgtataaacaaaaatttatccgtggcttctgtcacttgtgcgatggtcaggaagct
tgttctgtgggcctggaggccgggataaatcccaccgaccatgtcatcacatcctatcgg
gctcatggcttgtgctatactcgtggactctctgtccgatcaattcttgcagagctgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggatcgatgcatatgtatgtcaagaat
ttctatgggggcaatggcattgttggcgcacaggggcccctgggagctggcattgctctg
gcctgtaaatacaagggaaacaaggaggtctgtttggctctttatggggatggtgctgcg
aatcagggtcagatagctgaagctcacaatatggcagctttgtggaaattaccctgtgtt
ttcatctgtgagaataacctctatggaatgggaacccctgttgagagagcatcagccagc
actgattactataagagaggaaattttatccctggactgagggtagacggaatggatgtt
ctaggtgttcgggaggcaactaagtttgtagctgactactgtagatctggaaaggggccc
atagtgatggagctgcagacctaccggtatcatggacacagtatgagtgaccctgggatc
agttatcgtacccgagaagaagttcagaatgtgagaagggagagcgatcctattatgctt
ctcaaagacagaatggtaaacagtaagcttgccactgttgaggaactaaaggatattgat
gttgaagtgaggaaagaagttgaggatgcagcccagtttgctatgactgatcctgaacca
cctttggaagaattagctcatcacatctactgcaatactccagcttttgaagttcgtggt
gcaaaccagtggatcaagttcaagtccctcagttaa
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