Prionailurus bengalensis (leopard cat): 122483375
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Entry
122483375 CDS
T07574
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00230
Purine metabolism
pbg01100
Metabolic pathways
pbg04022
cGMP-PKG signaling pathway
pbg04740
Olfactory transduction
pbg04925
Aldosterone synthesis and secretion
pbg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122483375 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
122483375 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
122483375 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
122483375 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122483375 (PDE2A)
Enzymes [BR:
pbg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
122483375 (PDE2A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
122483375
NCBI-ProteinID:
XP_043436258
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Position
D1:59251110..59345425
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AA seq
942 aa
AA seq
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MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIHI
AGFQRAVKEALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKVREAVISRKRLGCN
GLGPSDLPGKPLARLMAPLAPDTQVLVMPLVDKEAGAVAAVILVHCGQLSDSEEWSLQAV
EKHALVALRRVQALQPRGPGAASAAVRNPPAGVAGDQKGGVAHTDQDQKILQLCGELYDL
DASSLQLKVLQYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLEEETSFPLTTGRLGQV
VEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDLFT
DQDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIIT
EARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIP
DAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATA
FSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSN
FASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWM
HAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALY
SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKD
LQKMAEVGYDRTNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKA
MGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVS
HKFTIRGLPSNNSLDFLDEEYEVPQLDGTGAPVNGCFSLDAE
NT seq
2829 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcggggccagcaggtcttcctcaagccggacgagccgccgccgccgccg
cagccatgcgccgacagcctgcaggatgctttgctgagcctgggctctgtcatccacatc
gcgggcttccagcgggctgtcaaggaggccctttcagctgtgctccccaaagtggagact
gtctacacttacctgctggatggggagtcccggctggtgtgtgaggaccccccccacgag
ctgccccaggaggggaaagtccgagaggctgtgatctcccggaagcggttgggctgcaat
ggactgggaccctcggacctgccggggaagccgttggccagactgatggccccactggct
cctgatacccaagtgctggtcatgccgctggtggacaaggaggctggggctgtggcagcc
gtcatcttggtgcattgtggccagctgagtgacagtgaagagtggagcctgcaagccgtg
gagaagcatgctctggtggccctgcgaagggtgcaggctctgcagccccgggggcctggc
gccgcctcggcagcagtccggaaccccccggcgggggtggcgggagaccagaagggcggt
gtggctcacaccgaccaggaccaaaagatcctgcagctgtgcggggaactctacgacctg
gatgcctcgtccctccagctcaaagtcctccaatacctgcagcaggagacccaggcatcc
cgctgctgcctcctgctggtgtccgaggataatctccagctttcctgcaaggtcatcgga
gataaagtgctggaggaagaaaccagctttccgttgacgacaggacgcctgggccaggtg
gtggaagataagaagtctatccagctgaaggatctcacctctgaggatgtgcaacagctg
caaagcatgttgggctgtgagctgcaggcgatgctctgtgttcctgtcatcagccgggcc
actgaccaggtggtggccttggcctgcgccttcaacaagctcgggggagacttgttcacg
gaccaggatgagcatgtgatccagcactgcttccactacactagcacggtgctcaccagc
accctggccttccagaaagagcaaaagctcaagtgtgagtgccaggctcttctccaagtg
gcaaagaacctctttactcacctggatgatgtctctgtcctgctccaggagatcatcaca
gaggccagaaacctcagcaatgctgagatctgctccgtgttcctgctggatcaaaatgag
ctggtggccaaggtgttcgacgggggcgtggtggatgacgagagctacgagatccgcatc
ccggctgaccagggcattgcgggccacgtggcaaccaccggccagatcctgaacatcccg
gacgcgtacgcgcatccgcttttctaccgtggcgtggacgacagcaccggcttccgcacg
cgcaacatcctctgcttccccatcaagaacgagaaccaggaggtcatcggtgtggccgag
ctggtgaacaagattaacgggccatggttcagcaagttcgacgaggacttggcaaccgcc
ttctccatctactgtggcatcagcatagcccattccctcctatacaagaaagtgaatgag
gcccagtatcgcagccacctagccaacgagatgatgatgtaccacatgaaggtctctgat
gatgaatacaccaaacttctccatgatgggatccagcctgtggctgccattgactccaac
tttgccagtttcacctatacccctcgctctctgcccgaggatgacacttccatggccatc
ctgagcatgctgcaggacatgaatttcatcaataactacaaaattgactgcccaactctg
gcccggttctgtttgatggtgaagaagggctaccgggatcccccctaccacaactggatg
catgccttttctgtctcccacttctgctacctgctctacaagaatctggagcttaccaac
tacctcgaggacatcgagatcttcgccttgtttatttcctgcatgtgtcatgacctggac
cacagaggcacaaacaattccttccaggtggcctcgaaatctgtgctggctgctctctac
agctccgagggctctgtcatggagaggcaccacttcgctcaggccatcgccatcctcaac
acccatggttgcaacatctttgaccacttctcccggaaggactatcagcgtatgctggac
ctgatgcgggacatcatcttggccaccgacctggcccaccacctccgcatcttcaaggac
ctccagaagatggccgaagtgggttatgaccgaacaaacaagcaacaccatagcctcctc
ctctgcctccttatgacctcctgtgacctctctgaccagaccaagggctggaagactacg
aggaagatcgcagagctgatctacaaagagttcttctcccagggagacttggagaaggcc
atgggcaacagaccgatggagatgatggaccgggagaaggcctacatccctgagctgcag
atcagctttatggagcatatcgcgatgcctatttacaagctgctgcaggacctgttcccc
aaggcggcagagctatatgaacgtgtggcctctaaccgtgagcactggaccaaagtgtct
cacaaattcaccatccgcggcctcccgagcaacaactcgctggacttcctggatgaggag
tacgaggtgcctcagctggatggcactggggcccctgtcaatggctgtttcagccttgat
gctgagtga
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