Prionailurus bengalensis (leopard cat): 122485185
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Entry
122485185 CDS
T07574
Symbol
NOS2
Name
(RefSeq) LOW QUALITY PROTEIN: nitric oxide synthase, inducible
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00220
Arginine biosynthesis
pbg00330
Arginine and proline metabolism
pbg01100
Metabolic pathways
pbg04020
Calcium signaling pathway
pbg04066
HIF-1 signaling pathway
pbg04146
Peroxisome
pbg04371
Apelin signaling pathway
pbg04926
Relaxin signaling pathway
pbg05010
Alzheimer disease
pbg05014
Amyotrophic lateral sclerosis
pbg05022
Pathways of neurodegeneration - multiple diseases
pbg05133
Pertussis
pbg05140
Leishmaniasis
pbg05142
Chagas disease
pbg05145
Toxoplasmosis
pbg05146
Amoebiasis
pbg05152
Tuberculosis
pbg05200
Pathways in cancer
pbg05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
122485185 (NOS2)
00330 Arginine and proline metabolism
122485185 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
122485185 (NOS2)
04066 HIF-1 signaling pathway
122485185 (NOS2)
04020 Calcium signaling pathway
122485185 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
122485185 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
122485185 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122485185 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
122485185 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
122485185 (NOS2)
05152 Tuberculosis
122485185 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
122485185 (NOS2)
05145 Toxoplasmosis
122485185 (NOS2)
05140 Leishmaniasis
122485185 (NOS2)
05142 Chagas disease
122485185 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
122485185 (NOS2)
05014 Amyotrophic lateral sclerosis
122485185 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
122485185 (NOS2)
Enzymes [BR:
pbg01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
122485185 (NOS2)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
NAD_binding_6
Motif
Other DBs
NCBI-GeneID:
122485185
NCBI-ProteinID:
XP_043439551
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All DBs
Position
E1:18669353..18702650
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AA seq
1315 aa
AA seq
DB search
MREGLGAACEAARPRLCRLLRRILRPQPAFGPRRASLVTQDDPKCHSLSKHRNEPPQSLT
GTVKTVPESLGKLDMPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDLACRSKSCLGAIMN
PKSLTRGPRDKPTPPDELLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQL
TGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNIR
SAITVFPQRSDGKHDFRIWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYGR
FDVVPLVLQADGGDPELFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVANMLLEVGG
LEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEINVA
VLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEML
NYVLSPFFYYQVEAWKTHIWQDEKRRPRRRKIPFKVLVQAVLFASMLMCKTMASRVRATI
LFATETGKSETLARDLGALFSCAFNPKILCMDEYGLSNLEEEQLLLVVTSTFGNGDSPGN
GEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGDE
LSGQEEAFRSWAVQTFKAACETFDVRGKHRVQIPKLYTSNVTWDPHHYRLVRDSQPLDLN
KALGSMHAKKVFTMRLKSQRNLQSAKSSRTTLLVELSCEDSHRLSYLPGEHLGVFPGNQL
ALVKGILERVVDGPAPHQPVRLETLSESGSYWVRDKRLPPCSLSQALTYFLDITTPPTQL
LLRKLAQLATEEAERQRLEILCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLP
ILKPRYYSISSSRACAPTEVHLTVAVLTYRTRGGQGPLHHGVCSTWLSSLKPQDPVPCFV
RSAGGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDTEHKGLRGSRMTLVFGCRRPDE
DHLYREEMLEMAQKGVLHEVHTAYSRLPGQPKVYVQDILRQKLASEVLRVLHEEQGHLYV
CGDVRMARDVAQTLKHLLAAKLSLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDGA
ARQPSDPRVPAAHGTSXSRCHRTXXWSQLPIIXGHRARRDGRKSXPGASRLSSPAPSPKP
YTXPAAGXQSGPSGTSGLPXAHPSRIMESWGFLGPLKTKLLCWAHLVGDKDEPSSDCTTL
RDHQEALSRHPVFSSPCTVIYASVFKKNNLQPXGPLGPSLYXLLDGDIYMEYILF
NT seq
3951 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgaggggctgggcgccgcgtgtgaggccgcccggccccggctctgccggctcctc
cgcaggatcctgcggccgcagcccgccttcggtccccgccgagccagtctagtgacacag
gatgaccccaagtgtcacagcctcagcaaacaccggaatgagcccccccagtccctcacg
gggacagtaaagacagttccagaatccctggggaagctggatatgcccccgtcggcctgc
ccacggcacgtgaggatcaaaaactggggcagtgggatgactttccaagacacacttcac
cacaaggccaaaggggatcttgcttgcaggtctaagtcttgtctgggagccatcatgaac
cccaaaagtttgaccagaggacccagggacaagcctacccccccagacgagcttctacct
caagctatcgaatttgtcaaccagtattacagctccttcaaagaggcaaaaatagaggaa
catctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctatcagctg
acgggagatgagctcatcttcgccaccaagcaggcttggcgcaacgccccccgctgcatc
gggaggatccagtggtccaacctacaggtcttcgacgcccggagctgttccactgcccag
gaaatgttcgagcacatctgcagacatgtgcgttatgctaccaacaatggcaacatcagg
tcggccatcaccgtgttcccccagcggagtgatgggaagcatgacttccggatctggaat
gctcagctcatccggtatgctggctaccagatgcctgatggcaccatcctgggggaccct
gccagcgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtacggccgc
tttgatgtggtgcctctggtcctgcaggctgatggcggagaccctgagctctttgaaatc
ccgcctgacctcgtgctcgaggtgcccatggaacatcccaagtatgagtggttccgtgaa
ctggagctaaagtggtatgccctgcctgccgtggccaacatgctgctcgaggtgggtggc
ctggagttcccagggtgccccttcaacggctggtacatgggcacggagatcggggtccgg
gacttctgtgacgttcagcgctacaacatcctggaggaagtgggcagaaggatgggcctg
gaaacgcacaagctggcctcactctggaaggaccgggctgtcattgagatcaacgtcgcc
gtgctgcacagttttcagaagcaaaacgtgaccatcatggaccaccactcggctgcggag
tccttcatgaagtacatgcagaatgagtaccggtcccgagggggctgtcctgccgactgg
atttggctggtgcccccgatttctggcagcatcactcccgtgttccaccaggagatgtta
aactatgtcctgtcccctttcttctactaccaggtggaggcctggaaaacccacatctgg
caggatgagaagcggagaccccggagaagaaagattccgttcaaagtcttggttcaagct
gtgctcttcgcctccatgctgatgtgcaagaccatggcgtcccgagtgagagccacaatc
ctctttgcgacggagacaggaaagtcagaaacactggcccgggacctaggggccttgttc
agctgtgccttcaaccccaagattctctgcatggacgagtacgggctgagcaacctggag
gaagagcagctactactggtggtgaccagcacgtttgggaacggagactcccccggcaac
ggagagaaactgaaaaaatccctcttcatgctgaaagagcttaccaacaagttcaggtat
gccgtgttcggcctcggctccagcatgtaccctcagttctgtgcctttgctcatgacatc
gaccagaagctgtcccatctgggggcctctcagcttgccccaacaggggaaggggacgag
ctcagtggacaggaggaagccttccgcagctgggccgtgcaaaccttcaaggcagcctgt
gagacgttcgatgtgcgaggcaagcaccgcgttcagatccccaagctctacacctccaat
gtgacctgggacccgcaccactacaggctcgtgcgggactcacagcctctggacctcaac
aaagccctcggcagtatgcacgccaagaaagtgttcaccatgaggctcaaatcacagcgg
aatctccagagtgcgaaatccagccgcaccaccctcctggtggagctctcctgtgaggac
agccaccggctgagctatctgcctggagagcacctcggggttttcccaggcaaccagctg
gctctggtaaaaggcatcttggagcgagtggtggacggccctgcgccccatcaaccggtg
cgcctggagaccctcagcgagagtggaagctactgggtcagagacaagcggctgcccccg
tgctcgctcagccaggccctcacctacttcctggatatcaccacccccccaacccagctg
ctgctccgcaaattggcacagctggccacagaagaggcagagaggcagaggctggagatc
ctgtgccagccctcagagtacaacaaatggaagttcaccaatagccccacattcctggag
gtactggaggagttcccatccctgcgggtgtctgctggcttcctgctctcccagctgcct
attctgaaaccccggtactactccatcagctcctccagggcctgtgcacccacggaggtc
cacctcactgtggctgtgctcacctaccgcacccgaggtggccaaggtcccttgcaccac
ggcgtctgcagcacatggctcagcagcctgaagccccaagacccagtaccctgctttgtg
agaagtgccggcggcttccagctccctgaggacccctcccaaccttgcatcctcattggg
cctggcacaggcatcgcccccttccgcagcttctggcagcagcggctccatgacaccgag
cacaaagggctccggggcagccgcatgaccctggtgttcgggtgccgccgcccggatgag
gaccacctctatcgggaggagatgttggagatggcccagaagggggtgctgcatgaggtt
cacacagcctactctcgcctgcctggccagcccaaggtctatgttcaagacatcctgagg
cagaagctggccagcgaggtgctccgcgtgctccatgaggagcaaggccacctttatgtc
tgtggggatgtgcgtatggcccgggatgtggcccaaaccctgaagcacctgctggccgcc
aagctgagcctgagcgaggagcaggtggaggactatttcttccaacttaagagccagaag
cgctatcatgaagacatctttggtgctgtatttccctacgaggtgaaaaaggatggggca
gcaaggcagcccagcgatcccagagttccagcggcccacgggacaagttaaagtcgctgc
cacagaacttaatgatggagccaactcccgattatctgaggtcacagggcccggagagat
ggaaggaaatcatagcccggagcctcacgtcttagttccccagctccttccccaccaaac
cctatacttgacctgctgccggctagcagtctggaccgagtggaacctctggtctccctt
gagcccacccttcccggataatggagagttggggcttcctgggtcccttgaagactaaag
ctgctgtgctgggctcacctggtgggtgacaaggatgaaccttcttctgattgcaccact
ttacgtgaccaccaggaggcgctgtcgcgccaccctgtatttagctccccactgtacagt
tatttatgcctctgtatttaaaaaaaacaacctccagccttaagggccgctcgggccgtc
cctgtatgactcctggatggagatatttatatggaatacattttattttaa
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