Prionailurus bengalensis (leopard cat): 122493003
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Entry
122493003 CDS
T07574
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04010
MAPK signaling pathway
pbg04020
Calcium signaling pathway
pbg04151
PI3K-Akt signaling pathway
pbg05200
Pathways in cancer
pbg05216
Thyroid cancer
pbg05223
Non-small cell lung cancer
pbg05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122493003 (RET)
04020 Calcium signaling pathway
122493003 (RET)
04151 PI3K-Akt signaling pathway
122493003 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122493003 (RET)
05230 Central carbon metabolism in cancer
122493003 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
122493003 (RET)
05223 Non-small cell lung cancer
122493003 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122493003 (RET)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122493003 (RET)
Protein kinases [BR:
pbg01001
]
Receptor tyrosine kinases (RTK)
RET family
122493003 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
122493003
NCBI-ProteinID:
XP_043452871
LinkDB
All DBs
Position
D2:complement(49426108..49479439)
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AA seq
1117 aa
AA seq
DB search
MAKATATAGAARLRLLLLLPLLGEAPLGLYFARDAYWEKLYVDQPAGMPLLYVHALRDMP
EEVPTFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSTWDKLSIRNGGFPVL
TIYLQVFLSPTSLREGECQWPGCARVYFSFVNTSFPACGSLKPRELCFPETGVSFRIREN
RPPGTFHQFRLLPVQFLCPNISVAYRLLEGENLPFHCAPDSLEVSTRWPLDRELREKYEL
VAACTVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGIDTASAVVEFKRKEGTVVAKIRV
FDADVVPASGELLKRYTNTLLSGDAWVLQTFRIEHSPNETLAQANGSFVRATVHDYRLVL
NRSLPISENRSLQLTVLVNDSDFQGPGEGTLFLHFNVSVLPVSLHLPSTYTFTVSRRARR
FAQIGKVCVENCQEFSGIHVQYRLQLSSTNCSVLGVVTSAEDTTGNLFVNDTEALQRPDC
SQLRYTVVAAERPTRKQTQALLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLT
GRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPG
ERWGIKAGFGICNCFPEEKKCFCEPEDTQEPLCDELCRTVIAAAVLFSFVVSMLLSTFCI
HRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSMDSMENQVSVDAFKIPEDPKW
EFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFN
LLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSSSY
LDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSR
DVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLD
LAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPL
TRADGTNTVCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3354 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggcgacggccggcgccgcgaggctgcggttgctgctgctgctgccg
ctgctcggcgaagctccgctgggactctatttcgccagggatgcttactgggagaaactc
tacgtggaccagccagctggcatgcccctgctctacgtccatgccctgcgggacatgccg
gaggaggtgcccaccttccgcctgggccagcacctctacggcatcgcctaccgtgcaagg
ctgcatgagaacgactggattcgcatcgaggaggacactggccttctctaccttaaccgg
agcctggatcacagcacctgggacaagctcagcatccgcaatggcggcttccctgtgctc
accatctacctccaggtcttcctgtcacctacatccctgcgtgagggcgagtgccaatgg
cccggctgtgcccgtgtgtacttctcctttgtcaacacctccttcccggcttgtggttcc
ctcaaaccccgggagctctgctttcctgagacaggtgtctccttccgcatcagagagaat
aggcctcctggcactttccaccagttccgcctgctgcctgtgcagttcctctgccccaac
atcagcgtggcctacaggctcctagaaggtgagaacctgcccttccactgcgccccggac
agcctggaggtgagcacgcgctggcccctggatcgcgagctgcgggagaagtatgagctg
gtggctgcttgcacggtgcgcgtcggcgcgcgcaaggaggaggtggtgatggtgcccttc
cccgtgaccgtgtatgatgaggacgactctgcgcccaccttcctcgggggcatcgacacc
gccagcgctgtggtggagttcaagaggaaggagggcactgtggtggccaaaatacgtgtc
ttcgatgcagacgtggtgccagcatccggggagctcctgaagcgatacacaaacacacta
ctctctggggatgcctgggtcctccagacattccgtatcgagcactcccccaacgagacc
ttggcccaggccaacggcagctttgtgcgggcaactgtgcatgactacaggctggttctc
aaccggagcctccccatctcggagaaccgctccctgcagctgaccgtgctggtcaatgac
tcggacttccagggccccggggagggcaccctcttcctccacttcaacgtgtccgtgctg
cctgtcagcttgcacttgcccagcacctacaccttcactgtgagcaggcgggcccgccgc
tttgcccagattgggaaagtctgtgtggaaaactgccaggagttcagcggcatccacgtg
cagtacaggctgcagctctccagcaccaactgcagtgtcctgggggtggtcacctcagcc
gaggacaccacagggaacctcttcgtgaacgacacagaagccctgcagcggcccgattgc
tctcaactccggtacacggtagtggctgccgaacggccaacccgcaagcagacccaggcc
ctgctggttgtcaccgtggaggggacatatgtggctgaggagccaggctgccccctgtcc
tgtgcagtcagcaagagacgccctgaatgtgaggagtgcggcggcctgggctctctgacg
ggcaggtgcgagtggagacagggagatggcaaaggaatcaccaggaacttctccacctgc
tcccccagcatcaagacctgccccgacggccactgtgatgccgtagagagcagaaatgtc
aacatctgcccccaggactgcctccggggcggcagcatcattggtggccatgagccaggg
gagcgctgggggattaaagctggcttcggtatctgcaactgtttcccagaggagaagaag
tgcttctgcgaacctgaagacacccaggagccgctgtgtgacgagctctgccgcacggtg
atcgcggccgctgtgctcttctccttcgtcgtctccatgctgctctccaccttctgcatc
caccgctaccacaagaacgcccacaagccacccattgcctctgctgagatgaccttccgc
cggcctgcccaggccttcccggtcagctactcctcgtccggcgcccgccggccctctatg
gactccatggagaaccaggtctctgtggacgccttcaagatcccggaggatccaaagtgg
gaattccctcgaaagaacttggttcttgggaaaaccctgggagaaggcgaatttggaaaa
gtggttaaggcgacagccttccggctgaaaggcaaagcagggtacacaaccgtggccgtg
aagatgctgaaagagaacgcttccccaagtgagctgcgggacctgctgtcagagttcaac
ctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcctgcagccaggac
ggcccgctcttcctcattgtggagtatgccaagtacggttccctgcggggcttcctccga
gagagccgcaaggcggggcccggctacgtgggcagcggaggcagccgcagctccagctac
ctggacaaccccgaggagcgggccctgaccatgggcgacctcatctccttcgcctggcag
atctctcgggggatgcggtacctggctgagatgaagcttgtgcatcgggacttggcagcc
agaaatgtcctggtagctgaggggcggaagatgaagatttcggattttggcctgtcccga
gacgtttatgaagaggattcctatgtgaagaggagcaagggtcggattccagtcaaatgg
atggcaattgagtctcttttcgatcatatctataccacccaaagtgatgtgtggtccttt
ggtgtcctgctgtgggagattgtgactctggggggcaacccctaccctgggatccctccg
gagcggcttttcaacctcctgaagacaggctaccggatggagaggcccgacaactgcagt
gaggagatgtacggtctcatgctgcagtgttggaagcaggaaccagacaagaggccagtg
tttgctgacatcagcaaagacctggaaaagatgatggttaagaacagagactacttggac
ctggctgcctccaccccatccgactccctgctttatgacgacggcctctcggaggaggag
acgcccctggtggactgtaataatgctcccctccctcgagccctcccctccacgtggatt
gaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgtaccactc
acgagagctgatggcactaacactgtgtgtccaagatatgcaaatgatagtgtatatgct
aactggatggtttcaccctcagcggcacaattaatggacgcatttgatagttaa
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