Physeter catodon (sperm whale): 102983319 Help Entry 102983319         CDS       T06011                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism pcad  Physeter catodon (sperm whale) Pathway pcad00230   Purine metabolism pcad01100   Metabolic pathways pcad01522   Endocrine resistance pcad04015   Rap1 signaling pathway pcad04022   cGMP-PKG signaling pathway pcad04024   cAMP signaling pathway pcad04062   Chemokine signaling pathway pcad04072   Phospholipase D signaling pathway pcad04114   Oocyte meiosis pcad04211   Longevity regulating pathway pcad04213   Longevity regulating pathway - multiple species pcad04261   Adrenergic signaling in cardiomyocytes pcad04270   Vascular smooth muscle contraction pcad04371   Apelin signaling pathway pcad04540   Gap junction pcad04611   Platelet activation pcad04713   Circadian entrainment pcad04714   Thermogenesis pcad04723   Retrograde endocannabinoid signaling pcad04724   Glutamatergic synapse pcad04725   Cholinergic synapse pcad04726   Serotonergic synapse pcad04727   GABAergic synapse pcad04728   Dopaminergic synapse pcad04750   Inflammatory mediator regulation of TRP channels pcad04911   Insulin secretion pcad04912   GnRH signaling pathway pcad04913   Ovarian steroidogenesis pcad04914   Progesterone-mediated oocyte maturation pcad04915   Estrogen signaling pathway pcad04916   Melanogenesis pcad04918   Thyroid hormone synthesis pcad04921   Oxytocin signaling pathway pcad04923   Regulation of lipolysis in adipocytes pcad04924   Renin secretion pcad04925   Aldosterone synthesis and secretion pcad04926   Relaxin signaling pathway pcad04927   Cortisol synthesis and secretion pcad04928   Parathyroid hormone synthesis, secretion and action pcad04934   Cushing syndrome pcad04935   Growth hormone synthesis, secretion and action pcad04970   Salivary secretion pcad04971   Gastric acid secretion pcad04972   Pancreatic secretion pcad04976   Bile secretion pcad05012   Parkinson disease pcad05030   Cocaine addiction pcad05031   Amphetamine addiction pcad05032   Morphine addiction pcad05034   Alcoholism pcad05163   Human cytomegalovirus infection pcad05166   Human T-cell leukemia virus 1 infection pcad05200   Pathways in cancer pcad05207   Chemical carcinogenesis - receptor activation pcad05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pcad00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102983319 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102983319 (ADCY5)    04371 Apelin signaling pathway     102983319 (ADCY5)    04072 Phospholipase D signaling pathway     102983319 (ADCY5)    04024 cAMP signaling pathway     102983319 (ADCY5)    04022 cGMP-PKG signaling pathway     102983319 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102983319 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102983319 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102983319 (ADCY5)    04062 Chemokine signaling pathway     102983319 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102983319 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102983319 (ADCY5)    04912 GnRH signaling pathway     102983319 (ADCY5)    04913 Ovarian steroidogenesis     102983319 (ADCY5)    04915 Estrogen signaling pathway     102983319 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102983319 (ADCY5)    04921 Oxytocin signaling pathway     102983319 (ADCY5)    04926 Relaxin signaling pathway     102983319 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102983319 (ADCY5)    04918 Thyroid hormone synthesis     102983319 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102983319 (ADCY5)    04916 Melanogenesis     102983319 (ADCY5)    04924 Renin secretion     102983319 (ADCY5)    04925 Aldosterone synthesis and secretion     102983319 (ADCY5)    04927 Cortisol synthesis and secretion     102983319 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102983319 (ADCY5)    04270 Vascular smooth muscle contraction     102983319 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102983319 (ADCY5)    04971 Gastric acid secretion     102983319 (ADCY5)    04972 Pancreatic secretion     102983319 (ADCY5)    04976 Bile secretion     102983319 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102983319 (ADCY5)    04727 GABAergic synapse     102983319 (ADCY5)    04725 Cholinergic synapse     102983319 (ADCY5)    04728 Dopaminergic synapse     102983319 (ADCY5)    04726 Serotonergic synapse     102983319 (ADCY5)    04723 Retrograde endocannabinoid signaling     102983319 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102983319 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102983319 (ADCY5)    04213 Longevity regulating pathway - multiple species     102983319 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102983319 (ADCY5)    04714 Thermogenesis     102983319 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102983319 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102983319 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102983319 (ADCY5)    05163 Human cytomegalovirus infection     102983319 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102983319 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102983319 (ADCY5)    05031 Amphetamine addiction     102983319 (ADCY5)    05032 Morphine addiction     102983319 (ADCY5)    05034 Alcoholism     102983319 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102983319 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102983319 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102983319 (ADCY5) Enzymes [BR:pcad01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102983319 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  102983319 NCBI-ProteinID:  XP_007106323 Ensembl:  ENSPCTG00005006482 UniProt:  A0A2Y9EQC1 LinkDB All DBs Position 1:91317485..91474247 Genome browser AA seq 1260 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGT VTPQQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQR RGAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAADELEAGAVE EDQGSGDGGSLAGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSS LTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLTAAVGVILVMAVLCNRAAFHQDHMGLA CYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALH LAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHS QRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSL ASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMG MDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKA GRIHITKATLNYLNGDYEVEPGGGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNR QRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLG RAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQIT IVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQRLSRKIVRSKMNSTLVGVFT ITLVFLSAFVNMFTCNSKDLFGCLADEHNISASEVNACHVVESDGNYSLGDERGFCGSPW PNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLL VTANAIDFNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQ ATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFS EFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYD KVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGN TVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPPS NT seq 3783 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctcggcgtggggcgaggccgactcccgcgccaat ggctacccccacgcccccgggggttcggcccgcggctccaccaagaaacccggggggacg gtgaccccgcagcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgac gatcctccgctgagtggcgatgaccccctggctgggggcttcggcttcagtttccgttcc aagtcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcggcagcgg cggggcgcggccggcgggggcagcacccgagcgccccctgcgggcggcggcggcggctcg gcggcggcggcggccgcagctggcgggacggaggtgcgcccccgttctgtggagctgggt ctggaggagcggcggggcaagggccgcgcggccgacgagctggaggccggcgccgtcgag gaagaccagggctccggagatggcggcagcttggcaggctcgggcgcggggcctggcgcg gtgctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctcgaagaagttc ccgtcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagc ctcactatgctcatggctgtgctggtgctcgtgtgcctcgtcatgttggccttccacgcg gcacggcccccgctgcagctgccctacctggccgtgctgacggctgccgtgggtgtgatc ctcgtcatggccgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcc tgctacgcgctcatcgccgtggtgctggctgtccaggtggtgggcctgctgctgccccag ccgcgcagcgcctccgagggcatctggtggactgtgttcttcatctatactatctacacg ctgctgcccgtgcgcatgcgggccgcggtactcagcggggtgctcctgtctgccctccac ctggccatcgccctgcgcaccaacgcccaggaccagttcctgctcaagcagctcgtctcc aacgtcctcattttctcctgcaccaacatcgtgggcgtctgcacccactacccggctgag gtctcccagagacaggccttccaggagacccgggagtgcatccaggctcggctgcactcg cagcgggagaaccagcagcaggagcggcttctgctgtctgtccttccccgtcacgttgcc atggagatgaaagcagacatcaatgccaaacaggaggatatgatgttccataaaatttac atccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagcctg gcgtcccagtgcaccgcccaggagcttgtcatgaccctcaacgagctcttcgcccgcttc gacaagctggctgcagagaatcactgtttacgtattaagatcctgggagattgttattac tgcgtctcagggctgcctgaagccagggctgaccatgcccactgctgcgtggagatgggc atggacatgattgaggccatctcgctggtccgggaggtgacaggtgtcaacgtgaacatg cgtgtgggaatccacagcgggcgagtgcactgtggcgtccttggcctcaggaagtggcag ttcgacgtctggtctaacgacgtcacgctggccaaccacatggaggctggaggcaaggcg ggacgcatccacatcaccaaggccacgctcaactacctgaatggcgactacgaagtggag ccgggcggtgggggcgagcgcaacgcctacctcaaagagcacagtatcgagaccttcctc atcctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaagatgaatcgc cagagaaccaactcgatcgggcacaacccaccacactggggggccgagcgccccttctac aaccacctgggtggcaaccaggtgtccaaggagatgaaacggatgggctttgaagatccc aaggacaagaacgcccaggaaagtgcgaaccccgaggatgaagtggatgaatttctgggc cgtgccattgacgccaggagcatcgacaggctacgatctgagcatgttcgcaagttcctc ttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattc ggtgcctacgtggcatgtgcctcgctcgtcttcctcttcatctgctttgtccagatcacc attgtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctgacc ttggtggtatttgtgtccgtgatctactcctgcgtgaagctcttcccggccccgctgcag aggctatccaggaagatcgtgcggtccaagatgaacagcaccctggtgggcgtgttcacc atcaccctggtgttcctgtcagcttttgtcaacatgttcacgtgcaactccaaggacctg tttggctgcctggcggacgagcacaacatcagcgccagcgaggtcaacgcatgccacgtg gtggagtcagatggcaactacagcctgggtgacgagcggggcttctgcggcagcccctgg cccaactgcaacttccccgagtacttcacctatagcgtgctgctcagcctgctggcctgc tccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctc atctacgtgcttgtcgttgaggtgcccggtgtcacgctctttgacaatgccgacctactg gtcacagccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcacgcg accaaggtggcgctgaaggtggtgacgcccatcattatctcggtctttgtgctggccctg tacctgcacgcccagcaggtggagtccaccgcccgccttgacttcctctggaaactgcag gccactgaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcac aacatcctgcccaaggatgtagccgcacacttcctggcccgcgagcggcgcaatgatgag ctctactatcagtcgtgtgagtgcgtggctgtcatgttcgcctccatcgccaacttctcc gagttctacgtggagctggaggccaacaacgagggcgtcgagtgcctgcggctgctcaac gagatcatcgccgactttgacgagatcatcagtgaggatcggttcaggcagctggaaaag atcaagaccatcggcagcacctacatggccgcctcgggcctcaacgactccacctatgac aaggtgggcaagactcacatcaaagctctggctgacttcgccatgaagctgatggaccaa atgaagtacatcaatgagcactccttcaacaacttccagatgaagattgggctcaatatc ggccccgtagtggctggggtgattggggcccgcaaacctcagtacgacatctggggcaat acagtgaacgtggccagccgcatggacagcaccggggtgcccgaccgcatccaggtcacc acagacatgtaccaggtgctggccgccaacacgtaccagctggagtgccggggtgtggtc aaggtcaagggcaaaggcgagatgatgacatacttcctcaacggagggcccccgcccagt tag

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