Physeter catodon (sperm whale): 102986441
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Entry
102986441 CDS
T06011
Symbol
PDHA2
Name
(RefSeq) LOW QUALITY PROTEIN: pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad00010
Glycolysis / Gluconeogenesis
pcad00020
Citrate cycle (TCA cycle)
pcad00620
Pyruvate metabolism
pcad00785
Lipoic acid metabolism
pcad01100
Metabolic pathways
pcad01200
Carbon metabolism
pcad01210
2-Oxocarboxylic acid metabolism
pcad04066
HIF-1 signaling pathway
pcad04922
Glucagon signaling pathway
pcad05230
Central carbon metabolism in cancer
pcad05415
Diabetic cardiomyopathy
Module
pcad_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102986441 (PDHA2)
00020 Citrate cycle (TCA cycle)
102986441 (PDHA2)
00620 Pyruvate metabolism
102986441 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102986441 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102986441 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102986441 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102986441 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102986441 (PDHA2)
Enzymes [BR:
pcad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102986441 (PDHA2)
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Motif
Pfam:
E1_dh
Motif
Other DBs
NCBI-GeneID:
102986441
NCBI-ProteinID:
XP_023982464
UniProt:
A0A2Y9T2Z3
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Position
7:16343006..16344579
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AA seq
393 aa
AA seq
DB search
MRKMLAAAVSSVLSVVTQKPANRVLVASCNYSNDATFEIKKSPKCDLYRLEEGPPVTAVL
TREDGLKYYRMMQTVRRMELKADQLKKQKFFRGFCHLCDGQDACCVGLEAGLNPTDHVIA
SCRAHGLCCTRGLSVPSIFAELTGRRGGCAEGEGGSMHMXADNFYGDNGIVGSQGPPGAG
IALACKYKGDNEVCXTLHGNGAANQGQISEAYNMAAVWHLPCIFICENNRYGMGTSVERA
AANTDYYKRGNFIPGLRVDGMEVLCVREATKVAADYCRSGKGPILMELLTYHYHGHSMSH
PGISYRTREEVQNLXKSHPIMLLKGKMVNNKLASIEELKEIDAEVRKEIDAAAQFAITDP
EPPLEELSRHIYSSNPPLEIRRANRWIRFKSVS
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggctgctgctgtctctagcgtgctctctgttgtcacccagaagccc
gctaacagggtgcttgtggcatcctgtaactattcaaatgatgctacatttgagattaag
aaatccccgaaatgtgatctttatcggttggaagagggtccccctgtcaccgcagtgctc
acccgggaggatgggctcaaatactacaggatgatgcagaccgttcgtcgaatggaattg
aaggcggatcagttgaaaaaacagaaattttttcgtggtttctgtcacttgtgtgatggt
caggatgcttgttgtgtgggtcttgaggctgggctaaatcccacggatcatgtcattgca
tcctgtcgggctcacggcttatgctgtactcgtggactttctgtcccatcaatttttgca
gagctgacaggtcgaagaggtggctgtgctgaaggagaaggagggtcaatgcatatgtag
gccgataacttctatggagacaatggcattgtcggctctcagggaccgccgggagctggt
attgctctggcctgtaaatataagggagacaacgaggtgtgttagactctacatgggaat
ggtgctgctaatcagggtcagatatctgaagcttataatatggcagctgtgtggcattta
ccttgtattttcatctgcgagaataaccgctatggaatgggaacatctgttgagagagca
gcagccaacactgattactacaagagaggcaatttcatccctggtctaagggtagatgga
atggaggttctatgtgttcgggaggcaactaaggttgcagctgactattgtagatctgga
aaggggcccatactgatggagctgctgacataccattatcatggacacagtatgagtcac
cctggaatcagttatcgtacacgagaagaagttcagaatttanagaagagccatcctatc
atgcttctcaaaggtaaaatggtaaacaacaaacttgccagtattgaagaattgaaggaa
attgatgctgaagtgaggaaagaaattgatgctgctgctcagtttgctataaccgatcct
gaaccacctttggaagaattaagccgtcacatctacagcagtaatccacctttggaaatt
cgtcgtgcaaatcggtggatcaggtttaagtcagtcagttaa
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