Physeter catodon (sperm whale): 102988053
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Entry
102988053 CDS
T06011
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad00010
Glycolysis / Gluconeogenesis
pcad00020
Citrate cycle (TCA cycle)
pcad00620
Pyruvate metabolism
pcad00785
Lipoic acid metabolism
pcad01100
Metabolic pathways
pcad01200
Carbon metabolism
pcad01210
2-Oxocarboxylic acid metabolism
pcad04066
HIF-1 signaling pathway
pcad04922
Glucagon signaling pathway
pcad05230
Central carbon metabolism in cancer
pcad05415
Diabetic cardiomyopathy
Module
pcad_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102988053 (PDHA1)
00020 Citrate cycle (TCA cycle)
102988053 (PDHA1)
00620 Pyruvate metabolism
102988053 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102988053 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102988053 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102988053 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102988053 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102988053 (PDHA1)
Enzymes [BR:
pcad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102988053 (PDHA1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
102988053
NCBI-ProteinID:
XP_007106988
Ensembl:
ENSPCTG00005011695
UniProt:
A0A2Y9ERP0
LinkDB
All DBs
Position
21:3574496..3594002
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVDVRKEIEDAAQFATADPEPP
LEELGYHIYCSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcactacggtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgttcgtcgaatggagttaaaagcagaccag
ctatataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggctggcataaaccccacagaccatctgatcacagcgtatcgggct
catggctttacgtttactcgtgggctttctgtccgagcaattctcgcagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtacgccaagaacttc
tacgggggcaatggcatcgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataacggaaaagatgaaatctgtttgactttgtatggtgatggcgctgctaat
cagggtcagatattcgaagcttataatatggcggctttgtggaaattgccttgtattttc
atttgtgagaataaccgctatgggatgggcacatctgtggagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggccacaaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagttagaagtaagagtgaccctatcatgcttctc
aaggataggatggtgaacagcaatcttgccagtgttgaagaactaaaggaaattgatgtt
gacgtgaggaaagaaattgaggatgctgcccagtttgctacagctgatcctgaaccacct
ttggaagaactcggctatcacatctactgcagcgatccgccttttgaagtccggggtgca
aaccagtggatcaagtttaagtccatcagttaa
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