Proteus columbae: F1325_12535
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Entry
F1325_12535 CDS
T06419
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pcol
Proteus columbae
Pathway
pcol00790
Folate biosynthesis
pcol01100
Metabolic pathways
pcol01240
Biosynthesis of cofactors
Module
pcol_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pcol00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
F1325_12535 (folC)
Enzymes [BR:
pcol01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
F1325_12535 (folC)
6.3.2.17 tetrahydrofolate synthase
F1325_12535 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QHN11238
UniProt:
A0A6I7DE98
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Position
complement(2614113..2615411)
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AA seq
432 aa
AA seq
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MSNIITAPKATSPLSVWLSYLEHLHSSAIDMGLERVGKVGKILNVLRPAPKVITVSGTNG
KGTTCHMLESILIASGLKVGVYSSPHLVRYTERVRIQGKELSENAFCDVFAEIEQARGDI
SLTFFEYGTLAALKLFQQAQLDVVILEVGLGGRLDATNIVDADIAAITSIALDHTDWLGA
DREHIGHEKAGIFRANHYAVVGEPDMPHSIAQVANEKQAKLFRRGTDWSFVIEGDHWQWR
CADCEFDALPIPNIPLANAATAMGVIRCLLKSDDKVSQAITQQSIVDGMSRAQLPGRFQV
ISQHPLVIFDVAHNPHAAGYLAEKLSQLPQKSDTQVRIVVGMLGDKDIAGTLACLTPLAD
HWYVAPLNEFRGASADVLAQHLEKPMVFDSVENAWQQAMSDAAPNDIVVVCGSFHTVAHV
MELLEKESVGGK
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgtctaatatcataactgctcctaaagccacatcgcctttgtcggtgtggctttcttat
cttgaacatttacactctagcgccattgatatggggttagagcgagtcggcaaggtagga
aaaatattaaacgtgttacgtcctgcgcctaaggtaatcactgtctcaggcacaaatgga
aaaggcacaacctgtcatatgctagagtcaatcttgatagcatcaggattgaaagtcggc
gtttatagctcccctcatcttgttcgttatacagaacgcgttcgtatccaaggcaaagaa
ctctccgaaaatgctttttgtgatgtttttgcagaaattgaacaagctagaggcgatatc
tcgctcactttttttgaatatggcactctggctgcgctgaagttatttcaacaagcacaa
cttgatgttgttattcttgaagtaggattaggcggtcggttagatgctacaaatatcgtt
gatgccgatattgctgctatcacaagtattgccctcgatcatactgattggttaggcgca
gatagagagcatattggtcacgagaaagccggtattttccgagccaatcattatgctgtt
gtgggtgagccagatatgcctcattccattgcacaagttgccaatgaaaaacaagccaag
cttttccgtcgtggaacagattggtcttttgttattgaaggcgatcactggcagtggcgt
tgtgctgattgtgaatttgatgcgctgccaatccctaatattccgctagccaatgcggcg
acagcgatgggggttattcgttgcttgcttaaatctgatgacaaagtcagccaagcaata
acacagcaaagtattgtcgacggtatgtctcgtgcacaattaccaggtcgttttcaggta
atttctcaacatcctttggttatctttgatgtggcacataatcctcatgcagcaggatat
ttagcggaaaagttatcacaattaccacaaaaatctgatactcaagtgcgtattgttgtt
ggtatgctgggtgataaagatatcgcaggcactttagcgtgcttaacaccattggctgat
cattggtatgtagctccacttaatgaatttcgtggtgcttctgcggatgtgttagctcaa
catctcgagaaaccaatggtattcgatagtgttgaaaatgcatggcaacaagcaatgtcc
gatgctgctcctaacgatattgttgtggtttgtggctcatttcatacagtcgcgcatgtg
atggaacttttggaaaaggagagtgtgggtggcaagtaa
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