Puma concolor (puma): 112857865
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Entry
112857865 CDS
T08890
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00140
Steroid hormone biosynthesis
pcoo00980
Metabolism of xenobiotics by cytochrome P450
pcoo01100
Metabolic pathways
pcoo05204
Chemical carcinogenesis - DNA adducts
Module
pcoo_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
112857865 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
112857865 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
112857865 (HSD11B1)
Enzymes [BR:
pcoo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
112857865 (HSD11B1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
Shikimate_DH
DUF1776
NAD_binding_2
2-Hacid_dh_C
Helicase_RecD
ADH_zinc_N
Motif
Other DBs
NCBI-GeneID:
112857865
NCBI-ProteinID:
XP_025776980
UniProt:
A0A6P6HMC1
LinkDB
All DBs
Position
Unknown
AA seq
292 aa
AA seq
DB search
MAFMKKYLPPILGIFLAYYYYSANEEFRPEMLQGKKVIVTGASKGIGEQMAYHLAKMGAH
VVVTARSKENLKKIVSHCMELGAASAHYIAGTMENMTFAEQFVAKAGKLMGGLDMLILNH
ITNTSMNLFSGDIHIVRRSMEVNFLSYVVLSATALPMLKQSNGSIVVVSSKAGKMASPLI
APYSASKFALDGFFSSIRMEHSVAKINVSITLCILGLINTDTAMNAISGIVNMEASPKEE
CALEIIKGGALRQEEVYYDNSVWTALLLGNPGRKILELFFLRSYSLDKFIIN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcccccccattctggggatcttcttggcctactactac
tattctgcgaatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggattggagaacagatggcctatcatctggcaaagatgggagcccat
gtggtggtgacagcaaggtctaaagaaaatctaaagaagatagtatcccattgcatggag
cttggagcagcctcagcacactacattgctggcaccatggagaatatgaccttcgcagag
caatttgttgccaaagctggaaagctcatggggggactagacatgcttattctcaaccac
atcaccaacacttctatgaatctgtttagtggtgatatccacatcgtgcgcagaagcatg
gaagtcaacttcctcagttatgtggtcctgagtgctactgccttgcctatgctgaagcag
agcaatggaagcattgttgtcgtgtcctcgaaggctgggaaaatggctagtccacttatt
gcgccctattctgcaagcaagtttgccctggatgggtttttctcctccatcaggatggaa
cattcagtggccaagattaatgtatcgatcactctctgtatcctcggcctcataaacaca
gacacagccatgaatgccatttctggaatagtcaacatggaggcatctccaaaggaagaa
tgtgccctggagatcatcaaagggggagctctgcgccaagaggaagtgtactatgacaac
tcagtctggacagctctcctgctgggaaatccagggaggaagattctggaactcttcttc
ttaagaagttatagtttggacaagtttataatcaactaa
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