Puma concolor (puma): 112858492
Help
Entry
112858492 CDS
T08890
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00010
Glycolysis / Gluconeogenesis
pcoo00020
Citrate cycle (TCA cycle)
pcoo00620
Pyruvate metabolism
pcoo00785
Lipoic acid metabolism
pcoo01100
Metabolic pathways
pcoo01200
Carbon metabolism
pcoo01210
2-Oxocarboxylic acid metabolism
pcoo04066
HIF-1 signaling pathway
pcoo04922
Glucagon signaling pathway
pcoo05230
Central carbon metabolism in cancer
pcoo05415
Diabetic cardiomyopathy
Module
pcoo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
112858492 (PDHA2)
00020 Citrate cycle (TCA cycle)
112858492 (PDHA2)
00620 Pyruvate metabolism
112858492 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112858492 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
112858492 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112858492 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112858492 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112858492 (PDHA2)
Enzymes [BR:
pcoo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
112858492 (PDHA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Chal_sti_synt_N
Motif
Other DBs
NCBI-GeneID:
112858492
NCBI-ProteinID:
XP_025777712
UniProt:
A0A6P6HPN7
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAAVSRVLSGVTQKPASRVLVASCNYSNDAMFAIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACSVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNKEVCLALYGDGAANQGQIAEAHNMAALWKLPCVFICENNLYGMGTPVERASAS
TDYYKRGNFIPGLRVDGMDVLGVREATKFVADYCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRTREEVQNVRRESDPIMLLKDRMVNSKLATVEELKDIDVEVRKEVEDAAQFAMTDPEP
PLEELAHHIYCNTPAFEVRGANQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgccgctgtctcccgcgtgttgtccggggtcacgcagaagccc
gctagcagagtgctggtggcatcctgtaactattcaaatgatgcgatgtttgcaattaag
aaatgtgatctttatcgcttagaagagggtccccctgtcacaacagtgctcacccgggag
gatgggctcaaatactacaggatgatgcagactgttcgccgaatggagctgaaggcagat
cagctgtataaacaaaaatttatccgtggcttctgtcacttgtgcgatggtcaggaagct
tgttctgtgggcctggaggccgggataaatcccaccgaccatgtcatcacatcctatcgg
gctcatggcttgtgctatactcgtggactctctgtccgatcaattcttgcagagctgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggatcgatgcatatgtatgtcaagaat
ttctatgggggcaatggcattgttggcgcacaggggcccctgggagctggtattgctctg
gcctgtaaatacaagggaaacaaggaggtctgtttggctctttatggggatggtgctgcg
aatcagggtcagatagctgaagctcacaatatggcagctttgtggaaattaccctgtgtt
ttcatctgtgagaataacctctatggaatgggaacccctgttgagagagcatcagccagc
accgattactataagagaggaaattttatccctggactaagggtagacggaatggatgtt
ctaggtgttcgggaggcaactaagtttgtagctgactactgtagatctggaaaggggccc
atagtgatggagctgcagacctaccggtatcatggacacagtatgagtgaccctgggatc
agttatcgtacccgagaagaagttcagaatgtgagaagggagagcgatcctattatgctt
ctcaaagacagaatggtaaacagtaagcttgccactgttgaggaactaaaggatattgat
gttgaagtgaggaaagaagttgaggatgcagcccagtttgctatgactgatcctgaacca
cctttggaagaattagctcatcacatctactgcaatactccagcttttgaagttcgtggt
gcaaaccagtggatcaagttcaagtccctcagttaa
DBGET
integrated database retrieval system
