Propithecus coquereli (Coquerel's sifaka): 105816316
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Entry
105816316 CDS
T08746
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00010
Glycolysis / Gluconeogenesis
pcoq00020
Citrate cycle (TCA cycle)
pcoq00620
Pyruvate metabolism
pcoq00785
Lipoic acid metabolism
pcoq01100
Metabolic pathways
pcoq01200
Carbon metabolism
pcoq01210
2-Oxocarboxylic acid metabolism
pcoq04066
HIF-1 signaling pathway
pcoq04922
Glucagon signaling pathway
pcoq05230
Central carbon metabolism in cancer
pcoq05415
Diabetic cardiomyopathy
Module
pcoq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105816316 (PDHA1)
00020 Citrate cycle (TCA cycle)
105816316 (PDHA1)
00620 Pyruvate metabolism
105816316 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105816316 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105816316 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105816316 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105816316 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105816316 (PDHA1)
Enzymes [BR:
pcoq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105816316 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
105816316
NCBI-ProteinID:
XP_012507155
Ensembl:
ENSPCOG00000020305
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPNGAGLALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgctgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccggctggaagagggtcctcctgtcacgacagtgctcaccagagaggac
gggctcaaatactacaggatgatgcaaactgtgcgccgaatggagttaaaggcagatcag
ctgtacaaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaggccggcataaatcccacagaccatctcatcacagcctatcgggct
cacggctttaccttcactcggggcctttctgtcagagaaattcttgcagagcttacagga
cgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgccaagaacttc
tatgggggcaacggcatcgtgggagcccaggtaccaaatggggctgggctggccttggcc
tgtaagtataatggaaaagatgaggtctgtctgactttatatggcgatggcgctgctaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccttgtattttc
atctgtgagaataatcgctatggaatgggaacgtccgtggagagagcagcagccagcact
gattactacaagagaggcgatttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgagaggcaacaaggtttgcagctgcctattgtagatctgggaaggggcctatc
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgaacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacaacaatcttgccagtgttgaagaattaaaggaaattgatgtg
gaagtgaggaaagaaattgaggatgctgcccagtttgccacggctgatcctgagccgcct
ttggaggaactaggttaccacatctacagcagcgacccgccttttgaagttcgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
DBGET
integrated database retrieval system
