Propithecus coquereli (Coquerel's sifaka): 105822702
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Entry
105822702 CDS
T08746
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00562
Inositol phosphate metabolism
pcoq01100
Metabolic pathways
pcoq01521
EGFR tyrosine kinase inhibitor resistance
pcoq04068
FoxO signaling pathway
pcoq04070
Phosphatidylinositol signaling system
pcoq04071
Sphingolipid signaling pathway
pcoq04115
p53 signaling pathway
pcoq04140
Autophagy - animal
pcoq04150
mTOR signaling pathway
pcoq04151
PI3K-Akt signaling pathway
pcoq04218
Cellular senescence
pcoq04510
Focal adhesion
pcoq04931
Insulin resistance
pcoq05165
Human papillomavirus infection
pcoq05166
Human T-cell leukemia virus 1 infection
pcoq05200
Pathways in cancer
pcoq05206
MicroRNAs in cancer
pcoq05208
Chemical carcinogenesis - reactive oxygen species
pcoq05213
Endometrial cancer
pcoq05214
Glioma
pcoq05215
Prostate cancer
pcoq05218
Melanoma
pcoq05222
Small cell lung cancer
pcoq05224
Breast cancer
pcoq05225
Hepatocellular carcinoma
pcoq05230
Central carbon metabolism in cancer
pcoq05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcoq05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105822702 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
105822702 (PTEN)
04070 Phosphatidylinositol signaling system
105822702 (PTEN)
04071 Sphingolipid signaling pathway
105822702 (PTEN)
04151 PI3K-Akt signaling pathway
105822702 (PTEN)
04150 mTOR signaling pathway
105822702 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105822702 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
105822702 (PTEN)
04218 Cellular senescence
105822702 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105822702 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105822702 (PTEN)
05206 MicroRNAs in cancer
105822702 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
105822702 (PTEN)
05230 Central carbon metabolism in cancer
105822702 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105822702 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105822702 (PTEN)
05214 Glioma
105822702 (PTEN)
05218 Melanoma
105822702 (PTEN)
05215 Prostate cancer
105822702 (PTEN)
05213 Endometrial cancer
105822702 (PTEN)
05224 Breast cancer
105822702 (PTEN)
05222 Small cell lung cancer
105822702 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105822702 (PTEN)
05165 Human papillomavirus infection
105822702 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105822702 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
105822702 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105822702 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pcoq01009
]
105822702 (PTEN)
Enzymes [BR:
pcoq01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
105822702 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
105822702 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
105822702 (PTEN)
Protein phosphatases and associated proteins [BR:
pcoq01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
105822702 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
105822702
NCBI-ProteinID:
XP_012515175
Ensembl:
ENSPCOG00000004892
UniProt:
A0A2K6EIG7
LinkDB
All DBs
Position
Unknown
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSSSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacagaaacaatatcgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgaaagacattatgacaccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ttgctaaagaatcatctggattatagaccagtggcactgttatttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccagttcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattgcctgtgtgtggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacgttcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagcatttgtagtatagagcgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaacgatcttgacaaagcaaataaagacaaggccaatcgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccatcgaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaata
acaaaagtctga
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