Phascolarctos cinereus (koala): 110205921
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Entry
110205921 CDS
T05867
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01522
Endocrine resistance
pcw04010
MAPK signaling pathway
pcw04015
Rap1 signaling pathway
pcw04068
FoxO signaling pathway
pcw04071
Sphingolipid signaling pathway
pcw04114
Oocyte meiosis
pcw04148
Efferocytosis
pcw04218
Cellular senescence
pcw04261
Adrenergic signaling in cardiomyocytes
pcw04370
VEGF signaling pathway
pcw04380
Osteoclast differentiation
pcw04550
Signaling pathways regulating pluripotency of stem cells
pcw04611
Platelet activation
pcw04613
Neutrophil extracellular trap formation
pcw04620
Toll-like receptor signaling pathway
pcw04621
NOD-like receptor signaling pathway
pcw04622
RIG-I-like receptor signaling pathway
pcw04625
C-type lectin receptor signaling pathway
pcw04657
IL-17 signaling pathway
pcw04658
Th1 and Th2 cell differentiation
pcw04659
Th17 cell differentiation
pcw04660
T cell receptor signaling pathway
pcw04664
Fc epsilon RI signaling pathway
pcw04668
TNF signaling pathway
pcw04670
Leukocyte transendothelial migration
pcw04714
Thermogenesis
pcw04722
Neurotrophin signaling pathway
pcw04723
Retrograde endocannabinoid signaling
pcw04728
Dopaminergic synapse
pcw04750
Inflammatory mediator regulation of TRP channels
pcw04912
GnRH signaling pathway
pcw04914
Progesterone-mediated oocyte maturation
pcw04917
Prolactin signaling pathway
pcw04926
Relaxin signaling pathway
pcw04932
Non-alcoholic fatty liver disease
pcw04933
AGE-RAGE signaling pathway in diabetic complications
pcw04935
Growth hormone synthesis, secretion and action
pcw04936
Alcoholic liver disease
pcw05014
Amyotrophic lateral sclerosis
pcw05020
Prion disease
pcw05022
Pathways of neurodegeneration - multiple diseases
pcw05132
Salmonella infection
pcw05133
Pertussis
pcw05135
Yersinia infection
pcw05140
Leishmaniasis
pcw05142
Chagas disease
pcw05145
Toxoplasmosis
pcw05152
Tuberculosis
pcw05161
Hepatitis B
pcw05163
Human cytomegalovirus infection
pcw05167
Kaposi sarcoma-associated herpesvirus infection
pcw05169
Epstein-Barr virus infection
pcw05170
Human immunodeficiency virus 1 infection
pcw05171
Coronavirus disease - COVID-19
pcw05205
Proteoglycans in cancer
pcw05208
Chemical carcinogenesis - reactive oxygen species
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcw05415
Diabetic cardiomyopathy
pcw05417
Lipid and atherosclerosis
pcw05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110205921 (MAPK12)
04015 Rap1 signaling pathway
110205921 (MAPK12)
04370 VEGF signaling pathway
110205921 (MAPK12)
04668 TNF signaling pathway
110205921 (MAPK12)
04068 FoxO signaling pathway
110205921 (MAPK12)
04071 Sphingolipid signaling pathway
110205921 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
110205921 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
110205921 (MAPK12)
04218 Cellular senescence
110205921 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
110205921 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110205921 (MAPK12)
04613 Neutrophil extracellular trap formation
110205921 (MAPK12)
04620 Toll-like receptor signaling pathway
110205921 (MAPK12)
04621 NOD-like receptor signaling pathway
110205921 (MAPK12)
04622 RIG-I-like receptor signaling pathway
110205921 (MAPK12)
04625 C-type lectin receptor signaling pathway
110205921 (MAPK12)
04660 T cell receptor signaling pathway
110205921 (MAPK12)
04658 Th1 and Th2 cell differentiation
110205921 (MAPK12)
04659 Th17 cell differentiation
110205921 (MAPK12)
04657 IL-17 signaling pathway
110205921 (MAPK12)
04664 Fc epsilon RI signaling pathway
110205921 (MAPK12)
04670 Leukocyte transendothelial migration
110205921 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
110205921 (MAPK12)
04914 Progesterone-mediated oocyte maturation
110205921 (MAPK12)
04917 Prolactin signaling pathway
110205921 (MAPK12)
04926 Relaxin signaling pathway
110205921 (MAPK12)
04935 Growth hormone synthesis, secretion and action
110205921 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
110205921 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
110205921 (MAPK12)
04723 Retrograde endocannabinoid signaling
110205921 (MAPK12)
04722 Neurotrophin signaling pathway
110205921 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
110205921 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
110205921 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
110205921 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
110205921 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
110205921 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110205921 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
110205921 (MAPK12)
05161 Hepatitis B
110205921 (MAPK12)
05171 Coronavirus disease - COVID-19
110205921 (MAPK12)
05163 Human cytomegalovirus infection
110205921 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
110205921 (MAPK12)
05169 Epstein-Barr virus infection
110205921 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
110205921 (MAPK12)
05135 Yersinia infection
110205921 (MAPK12)
05133 Pertussis
110205921 (MAPK12)
05152 Tuberculosis
110205921 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110205921 (MAPK12)
05140 Leishmaniasis
110205921 (MAPK12)
05142 Chagas disease
110205921 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
110205921 (MAPK12)
05020 Prion disease
110205921 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
110205921 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110205921 (MAPK12)
05418 Fluid shear stress and atherosclerosis
110205921 (MAPK12)
05415 Diabetic cardiomyopathy
110205921 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
110205921 (MAPK12)
04932 Non-alcoholic fatty liver disease
110205921 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
110205921 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
110205921 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110205921 (MAPK12)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
110205921 (MAPK12)
Protein kinases [BR:
pcw01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
110205921 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
RIO1
APH
Kdo
Kinase-like
Haspin_kinase
FTA2
UvrD_C
Motif
Other DBs
NCBI-GeneID:
110205921
NCBI-ProteinID:
XP_020838538
UniProt:
A0A6P5K036
LinkDB
All DBs
Position
Unknown
AA seq
388 aa
AA seq
DB search
MSSPPPPRKGFYRQEVTKTEWEVRELYRDLQPVGSGAYGAVCSAIDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDDTLDDFTDFYLVMPFMGTDLSKLM
KHEKLSDDRIQFLVYQILRGLKYIHAAGIVHRDLKPGNLAVNEDCELKILDFGLARQTDS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKILFKGSDHLDQLMEIMK
VTGTPPPEFVQRLQSQDAKSYMESLPELEKKDFASVLENATPLAVNLLEKMLVLDAEKRV
TAAEALTHPYFETVHESEEEPQAQLYDDSFDDVDRTLEEWNESHTKKFSALSLLGSWIQR
RHLCDWMLRWKEGSLRFRPVGTLMVTPS
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgagctcccctccgcccccccggaagggcttttaccggcaagaggtcactaagactgag
tgggaggtgcgggaactctaccgggacctgcagcccgtgggctcgggggcttacggggcc
gtttgctcggctattgacagcaggacgggcaccaaggtggctatcaagaagctgtaccgt
cccttccagtcggagctgtttgcgaagcgcgcataccgggagctgcgtctactcaaacac
atgcggcacgagaacgtgattggcttgctggatgtcttcacccccgatgacacactggat
gacttcacggacttttacctggttatgccgttcatgggcacagacctcagcaagctgatg
aaacacgagaagcttagtgacgaccggatccaattcttggtctaccagatccttcgaggc
ctcaagtacatccatgccgctggcatcgtccacagggatctcaaacctggtaacctggcc
gtgaatgaggattgtgagctgaagattctggactttggcctggccagacagacagacagt
gagatgacgggctatgtggtgaccagatggtaccgggcacccgaggtcatccttaactgg
atgcattacactcagacagtggatatctggtctgtgggctgcatcatggcagaaatgatc
actgggaagattcttttcaaaggcagcgaccacctggaccagctgatggagatcatgaag
gtgacaggaacgcctcccccagagtttgtacagaggcttcagagtcaggatgcaaagagc
tacatggaaagtctccccgagctggagaagaaggactttgcttctgtcctggagaacgcc
acccccttggctgtgaatctgctggagaagatgttggtactggacgctgagaagcgagtg
acggccgccgaggcgctgacccacccatactttgagactgtgcatgagtccgaggaggag
ccacaggcccagctgtatgatgactcctttgatgatgtcgaccggaccctggaagagtgg
aacgagtcacatacaaagaagttctcagctttaagcctcctcggctcctggattcaaagg
agacatctctgtgactggatgctgagatggaaagaggggtccctcagattcaggccagta
gggactcttatggtgactcctagttga
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