Phascolarctos cinereus (koala): 110210843
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Entry
110210843 CDS
T05867
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00010
Glycolysis / Gluconeogenesis
pcw00020
Citrate cycle (TCA cycle)
pcw00620
Pyruvate metabolism
pcw00785
Lipoic acid metabolism
pcw01100
Metabolic pathways
pcw01200
Carbon metabolism
pcw01210
2-Oxocarboxylic acid metabolism
pcw04066
HIF-1 signaling pathway
pcw04922
Glucagon signaling pathway
pcw05230
Central carbon metabolism in cancer
pcw05415
Diabetic cardiomyopathy
Module
pcw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110210843 (PDHA1)
00020 Citrate cycle (TCA cycle)
110210843 (PDHA1)
00620 Pyruvate metabolism
110210843 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110210843 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110210843 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110210843 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110210843 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110210843 (PDHA1)
Enzymes [BR:
pcw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110210843 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
110210843
NCBI-ProteinID:
XP_020845596
UniProt:
A0A6P5KMD5
LinkDB
All DBs
Position
Unknown
AA seq
395 aa
AA seq
DB search
MRKMLAIVSRVLTGASQKPGAASEAGRVLLAARNFANDASFDIKKCDVHRLEDEPPTTAV
LTREEGLKYYKIMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCMGLEAGINPTDHVI
TAYRAHGFTYTRGLPVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGA
GIALACKYNGKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVER
AAASTDYYKRGDFIPGIRVDGMDVLCVREATKFAAAYCRSGKGPMLMELQTYRYHGHSMS
DPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATA
DPEPPLEELGYHIYSREPPFEVRGANQWIKYKSVS
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgcggaaaatgctcgctatcgtttcccgcgtgctgactggcgcctcccagaaaccggga
gctgctagtgaggctggaagagtgctattggcagcccgaaactttgcaaatgatgcttcg
tttgatattaagaaatgtgacgttcatcggctggaggatgaacctcccaccacagcagtt
ctcactagagaggaaggactcaagtattataagatcatgcagactgtccgtcggatggaa
ttgaaagcggaccagctgtataagcaaaagatcatccgtggtttctgccacttatatgat
ggtcaggaagcttgttgtatggggcttgaagctggtataaatcctacagatcatgtgatt
acagcctatcgagctcatggctttacctatactcgtggtcttcctgttcgagaaattctg
gcagagcttacaggacgaagagggggatgtgccaaaggaaaaggaggctctatgcacatg
tatgccaagaacttctatggtggcaatggcattgttggagctcaggtgcctttgggagct
ggtattgccctagcctgtaagtacaatggaaaagatgagatctgtttaactttgtacgga
gatggtgctgctaatcagggtcagatatttgaagcttacaatatggcagctttgtggaaa
ttgccttgtattttcatttgtgagaataatcgatatggaatgggaacttctgtagaaaga
gcagcagccagcactgactattacaaaagaggagactttattccaggaataagggtagat
ggtatggatgttctttgtgtccgtgaggcaacaaaatttgcagctgcctactgtagatca
ggaaagggccccatgttgatggaactacagacatatcgttatcatggacacagcatgagt
gaccctggtgtcagttatcgtactcgggaagaaattcaggaagtgaggagtaagagtgac
cctatcatgcttctcaaagatagaatggtgaacaacaaccttgccagtgttgaagaatta
aaggaaattgatgttgaagtaaggaaagagattgaagatgccgcccagtttgctacagct
gatccagagccacctttggaagaattgggctatcacatctacagccgagagccacctttt
gaagttcgaggtgcaaatcagtggatcaagtacaaatctgtcagctaa
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