Phyllostomus discolor (pale spear-nosed bat): 114494312
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Entry
114494312 CDS
T07739
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00270
Cysteine and methionine metabolism
pdic00480
Glutathione metabolism
pdic01100
Metabolic pathways
pdic01240
Biosynthesis of cofactors
pdic04216
Ferroptosis
Module
pdic_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
114494312 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
114494312 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
114494312 (GCLC)
Enzymes [BR:
pdic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
114494312 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
114494312
NCBI-ProteinID:
XP_028365132
EnsemblRapid:
ENSPDIG00005007711
UniProt:
A0A6J2LBJ0
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Position
4:complement(124769378..124814218)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLNIYHAVKDRHKDVLKWGDEVEYMLVSFDH
EHEKVQLILFGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRQEATSLLKENQALCTITSFPRLGCPGFTLPEFKPNRVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIEIFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNKYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYKQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQRRDAVR
QGMFYFRKDICKGGNAVVDGCGRAQNSPELATEEYTLMSIDTIINGKEGVFPGLIPILNS
YLESMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDKMNYS
LILKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggattctccagttcctgaacatctatcacgccgtcaaggaccgg
cataaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaacatgaaaaagtccaattgatcctgtttggagaggaacttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccacccgacactttggagacctgagtatgggagttac
atgattgaagggacacccggacagccgtatggagggaccatgtccgagttcaacacagtt
gaagacaacatgagaaaacgccggcaggaggcgacttctttattaaaagaaaatcaagct
ctttgcacaataacttcatttcccagattaggctgcccggggttcacgctgcctgagttc
aaacccaatcgggtcgaaggtggagcctctaagtcgctcttctttcctgatgaagcaata
aacaagcacccccgcttcagcaccctgacaagaaatatccgacacaggaggggagaaaag
gttgtcatcaatgttccaatatttaaggataagaacacaccgtctccatttatagaaata
tttcctgaggatgatgaggcagcaaaggcctcaaagccagatcacatctacatggatgcc
atgggattcgggatgggcaattgctgtcttcaggtaaccttccaggcttgcagcatatct
gaggctagatacctatatgatcagttggccactatctgcccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtcatt
tctgcatctgtagatgatagaactcgggaggaaagaggcctggagccactgaagaacaat
aagtatcggattagtaaatcccgatatgattcaatagacagttatttatctgagtgtggc
gagaaatacaatgacattgacttgacaatagataaagaaatctacaaacagctgttacag
gaaggcattgatcatctcctggcccagcatgtcgctcatctctttattagagacccactg
actctgtttgaggagaaaatacacctggatgatgccaatgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagcctcctcctccgaactcagatatt
ggatggagagtagaattccggcccatggaggttcagttaacagacttcgagaactctgcg
tatgtggtgtttgtggtgctgctcaccagagtgatactttcgtacaaactggattttctc
attccactgtcaaaggttgatgaaaacatgaaagtagcacagagacgagatgctgttcgg
cagggaatgttctatttcaggaaagatatttgcaaaggcggcaacgctgtggtggatggc
tgtggtagggcccagaacagcccggagctggccacagaggagtacaccctgatgagcatc
gacaccatcatcaacgggaaggaaggcgtgtttcctgggctgattccgattctgaactcc
taccttgaaagcatggaagtggatgtggacacccgatgcagtattctgaactacctaaag
ctgattaagaagagagcatctggagagctaatgacagttgccaggtggatgagggagttt
atcgcaaaccatcctgactacaagcaagacagtgtaataactgataaaatgaactacagc
cttatcttaaagtgtaaccaaattgcaaatgaattatgtgagtgcccagagttacttgga
ccagcgtttaggaaagtgaaatatagcggaagtaaaactgactcttccaactag
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