Phyllostomus discolor (pale spear-nosed bat): 114495472
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Entry
114495472 CDS
T07739
Symbol
HSD17B8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8 isoform X3
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00061
Fatty acid biosynthesis
pdic00140
Steroid hormone biosynthesis
pdic01100
Metabolic pathways
pdic01212
Fatty acid metabolism
Module
pdic_M00873
Fatty acid biosynthesis in mitochondria, animals
pdic_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
114495472 (HSD17B8)
00140 Steroid hormone biosynthesis
114495472 (HSD17B8)
Enzymes [BR:
pdic01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
114495472 (HSD17B8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
114495472 (HSD17B8)
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Gene cluster
GFIT
Motif
Pfam:
adh_short_C2
adh_short
KR
RmlD_sub_bind
Epimerase
RNA_pol_Rpb1_4
Motif
Other DBs
NCBI-GeneID:
114495472
NCBI-ProteinID:
XP_028366564
EnsemblRapid:
ENSPDIG00005002396
UniProt:
A0A6J2LHX3
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Position
4:106215458..106217678
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AA seq
255 aa
AA seq
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MAAQLRLRSAVALVTGAGSGIGRAVSVRLAQEGAAVAACDLDGAAARETVQLLGGPGSEK
RAHAAFQTDVSEAGSARRLLEQVQACFTRPPSVVVSCAGITRDEFLLHMSEDDWDKVIAV
NLKGIFLVTQAAAQALVSSGCHGSIINISSIIGKVGNMGQTNYSASKAGVIGLTQTVARE
LGRYGIRCNSVLPGFITTPMTQKVPQKVLDKITAMIPVGHLGNPEDVADVVAFLASDDSG
YITGASVEVTGGLFM
NT seq
768 nt
NT seq
+upstream
nt +downstream
nt
atggcggctcagctccggctccgctctgcagtagccctggtcacaggtgcgggtagcggc
atcggccgagcagtcagtgtgcgcctggcccaagagggggctgcagtggctgcttgcgac
ctggacggggcagcggcacgggagacggtgcagctgctgggcgggccagggagcgagaag
agggcccacgctgccttccagactgatgtgtctgaggccgggtccgccaggcgcctgctg
gaacaagtgcaggcctgctttactcgcccaccatctgtcgtcgtgtcctgtgcgggcatt
accagggatgagtttctacttcacatgtctgaggatgactgggacaaagtcatagctgtt
aacctcaagggcatctttctagtcactcaggcagcagcccaagccctggtgtccagtggt
tgtcatggctccatcatcaacatcagtagcatcatagggaaggtggggaacatgggacag
acaaactactcagcgtccaaggctggagtgattgggctgacccagactgtagctcgggag
ctcggacgatatgggatccgctgtaactctgtccttccggggttcattacaacacccatg
acacagaaagtgccacagaaagtgctggacaagataactgcaatgatcccagtgggacat
ctgggaaaccctgaggatgtggcagatgtggtcgccttcttggcatctgatgacagtgga
tacatcaccggggcctcagtggaagtcaccggaggtcttttcatgtaa
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