Phyllostomus discolor (pale spear-nosed bat): 114496437
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Entry
114496437 CDS
T07739
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00562
Inositol phosphate metabolism
pdic01100
Metabolic pathways
pdic04014
Ras signaling pathway
pdic04015
Rap1 signaling pathway
pdic04020
Calcium signaling pathway
pdic04024
cAMP signaling pathway
pdic04070
Phosphatidylinositol signaling system
pdic04919
Thyroid hormone signaling pathway
pdic04933
AGE-RAGE signaling pathway in diabetic complications
pdic05205
Proteoglycans in cancer
Module
pdic_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
114496437
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
114496437
04015 Rap1 signaling pathway
114496437
04020 Calcium signaling pathway
114496437
04070 Phosphatidylinositol signaling system
114496437
04024 cAMP signaling pathway
114496437
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
114496437
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
114496437
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
114496437
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pdic04131
]
114496437
Enzymes [BR:
pdic01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
114496437
Membrane trafficking [BR:
pdic04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
114496437
Endocytosis
Macropinocytosis
Phospholipase C
114496437
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
114496437
NCBI-ProteinID:
XP_035883411
UniProt:
A0A7E6DW62
LinkDB
All DBs
Position
5:147979658..148203636
Genome browser
AA seq
1995 aa
AA seq
DB search
MHLDNQQMYPTDSAKGLRFGTGLGFCAASEAESLRRGKQAVSWGFAGSHPALRVGWLFPL
SSVPNFTFLKDGCGCWRLKGDKIYNAVRRGEETEDTVGSLLHFFTKLPVSETAHERINIG
PCLKQCVPDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGLLNTFGGSTGRMMLKER
QPGTSVANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQNIYRRVLPVDYLCFL
TQNLGTPECQRSLPCLKASISASILNPQNGEHNALEDLVLRFNEVSSWVTWLILTAGSME
EKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFMDQSDLETMRSLKDAMA
QHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLVKLCPRYNSQEETLEF
VADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSRSLETEDEDSASEGNSSRKNS
LKDKARCQFIIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHGTELIPWYVLSIRADVHQ
FLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPASAKAKLGVLSNTSEPGK
FPLLGNAGLSGLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLSNVFLSETGVTLLYGLQ
TTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQYVSLYQEEGRYEG
PTLAHAVELFGGRRWSTRNPSPGTSAKSGEKPNMQRNNTLGISTTKKKKKILMRGESGEA
TDDEMATRKAKVHKECRSWSGSDPQDINEQEESEANAITSPPNLLPSRRAHSLTTAGSPN
LAAGTPSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMKGFQSFMVSDSNMSFVEFVE
LFKSFSVRSRKDLKDLFDLYAVPCNRLGSESAPLYTNLTIDENTSGLQPDLDLLTRNVSD
LGLFIKSKQQLSDSQRQISDAIAAASIVTNGTGVESTSLGIFGVGILQLNDFLVNCQGEH
CTFDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKNDESQENIKELQLPLSY
YYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKI
PFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVAKFLFESDFS
DDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAYNGGNANPPPANNE
EEEDEEDEYDYDYESLSDDVLTASPAPNCQEDNILEDRPENKSCNDKLQFEYSEEIPKRI
KKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASG
SSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSYEGIRQAWEESSSPLSPSTSLSA
IIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTTCQLLRTYPAATRIDSSNPNPLMFWLH
GIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNME
PAVYSLTVVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFFFR
VYFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRR
MEENSSGSTVPASLMFTTEERKCFQAHRVTVHGVPGPEPFTVFSINGGTRAKQLLQQILT
SEQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILNSWFPEEGYVGRI
VLKTQQENLEEKSIVQDDKEVILTSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQ
TLCKAKYSYSILSNPNPSDYVLLEEVVKDTANKKSSTPKSSQRVLLDQECVFQAQSKWKG
AGKFILKLKEQVQASREDKRKGISFASEFKKLTKSTKQPRGLTSPSQVLTSESVQNKEEK
PVGSLSSSDVTDYRQ
NT seq
5988 nt
NT seq
+upstream
nt +downstream
nt
atgcatcttgacaatcagcagatgtacccaacagattctgcaaagggattaagatttggc
accggacttggtttctgtgcagcctctgaggctgagagtctcaggagagggaagcaggct
gtcagctggggctttgcaggctctcatcctgccttgagggttggttggctcttccctctc
tcttcagtacccaattttaccttcttaaaggatggatgcggatgctggaggcttaaagga
gacaagatctacaatgcagtgagaaggggagaagaaacagaagatacagttggatctctt
ctccatttcttcacaaagctcccagtctctgagacagcccatgaaaggattaacatcggt
ccctgcttaaagcaatgtgtcccagataccgtatgtgagtatcgggccaccctccaaagg
acttccatatctcagtacatcaccggttctctcctagaagcaaccacatctttaggagca
agaagtggccttctcaatacttttggaggatccaccggacgaatgatgctgaaagaacgc
caaccaggcacctctgtggccaattccagtgccctcccttcaagttcagctgggatcagc
aaggaactgattgatctgcagcccctcatccagtttcctgaggaagttgccagcatcctg
atggagcaggagcagaatatttaccgaagggtcttgccggttgactatctttgcttcttg
acccagaatttgggcactccagaatgtcagaggtccctgccctgcctcaaagcatccatc
tcagcatccattcttaaccctcagaatggagagcacaatgcccttgaagatcttgtgttg
agatttaatgaggtgagctcctgggtgacgtggctgatcctcacggcgggctccatggag
gagaagcgggaggtcttctcctatttggtgcatgtggccaaatgctgctggaacatgggc
aactacaacactgtcatggagttcttggccggcctcagatcaagaaaagttttaaagatg
tggcagtttatggaccagtctgacctggagaccatgaggagcctgaaggacgccatggct
cagcatgagtcttcctgcgagtacaagaaggtggtgacacgggcgctgcacatccccggc
tgtaaggtggttccattctgcggggtgtttctgaaggagctctgtgaagtactagacgga
gcctctggcctggtgaagctctgcccaagatacaattcccaagaggaaactctagagttt
gtagctgactacagtggacaagataattttttacaacgcgtgggacaaaatggcttaaag
aattcggagaaagagtccaccgtcaacagcatctttcaggtcatccggagctgcagccgg
agtctggagacagaggacgaggacagcgccagtgaagggaacagctctaggaaaaactcc
ttgaaggataaagctcgatgccagtttataattggagatttgctggatacggaaaatgac
atctttgagcagcccaaagaatgggaccctcatggattagaagagccacagaaggccttt
gaccatgggacggagctcatcccgtggtacgtcctgtccatccgagctgatgtgcaccag
ttcctgctgcagggggccacggttatccactatgaccaggacacacacctctcggcccgc
tgcttcctccagctccagcctgacaatagcactttaacctggataaagcccaccactgcc
tccccagccagcgctaaagcaaaacttggtgtgcttagtaatacatctgaacctggcaaa
ttcccattattgggcaacgctggattaagtggcctggtggagggggtcttggatctgttt
tcagcaaaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcag
aacaaactgagtaatgtgtttctctcagagaccggtgtgacactgctctatgggcttcag
accactgacaatagattattgcactttgtggcaccaaagcacacagctaagatgctcttc
agcgggttgttggaactcactagagctgtgagaaagatgaggaagttccctgaccaaaga
caacagtggctgcggaaacagtacgtcagcctctatcaggaggaaggacggtatgaaggc
cccactttggctcatgctgtggagctgtttggtggcagacggtggagcactcgaaaccct
agccctgggacatctgcaaagagtggcgagaagcccaacatgcagaggaacaacaccttg
ggcatcagcactaccaagaaaaagaagaaaatccttatgaggggggagagcggagaggcg
accgacgacgagatggccacccgaaaggccaaagtgcacaaagagtgtcggagctggagt
ggttctgaccctcaagacattaatgaacaagaagaatcagaggcgaatgccatcacaagc
ccgcctaaccttctcccttccagaagagcccactctctgaccacggctgggtcccctaac
ttggctgctgggacgccatctcccatcaggccagtgtcctcccctgtgctgtcttcaaac
aagagcccgtccagtgcttggagcagcagcagctggcacgggcgcatcaaaggaggaatg
aaaggctttcagagcttcatggtttccgacagtaacatgagtttcgtcgaatttgttgag
ctgttcaaatccttcagtgtaaggagccgcaaagacctgaaggatctctttgacctctat
gccgtgccctgcaaccgactgggctctgagtcggccccactctacaccaacctaaccatt
gacgaaaacaccagcggtctgcagcctgacctagatttgttgaccagaaatgtctcggat
ttggggttgttcattaagagtaaacaacagctgtcagacagccagaggcagatctcggac
gccattgctgctgcaagcatcgtgacaaatggcactggggtcgagagcacatccctgggc
atatttggggttggcatacttcagctcaacgactttctagtgaattgccaaggagagcac
tgcacttttgatgaaatcctcagcatcatccagaagtttgagcctagcattagtatgtgt
caccagggcctaatgtcatttgaaggatttgcaaggtttctgatggataaagataatttt
gcatcaaaaaatgatgaatcacaggagaacattaaagaattacagctgcccctgtcctac
tattacattgaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcc
tcagtagaactctacagccaggtcctcctgcaaggctgcaggagtgtagagttggactgc
tgggacggagatgacgggatgcccatcatttatcatggacacacactgacaaccaagatc
cccttcaaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctgcca
atcatcatatcaattgagaaccattgttcattgcctcagcaacgaaaaatggcagaaatt
ttcaagactgtgtttggagaaaaactggtggctaaattcttatttgagagtgatttctca
gatgatcccatgcttccttcacctgaccaacttagaaggaaggtgcttcttaaaaataag
aagctaaaagctcatcagacgccggtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcctataatggtgggaatgccaaccccccacctgctaataacgag
gaggaggaggatgaagaggacgagtatgattatgactatgaatccctctctgatgatgtc
cttactgcttctcctgctcctaactgtcaggaagacaacattctagaagacagacctgaa
aataaatcatgtaacgacaagcttcagtttgagtatagtgaagaaattcccaagaggata
aagaaagcagataactctgcttgcaacaaaggaaaggtatatgacatggaattgggagaa
gaattttatcttcctcagaataaaaaggaaagcagacagattgcacccgagctttctgac
cttgtcatctattgccaagcagtaaaatttccaggcctgtcaactctaaatgcatctggc
tctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcaga
atgagccctggggagacagcatcatttaacaaaacatctggaaaaagttcctatgaagga
atacgacaggcctgggaggagtcttcttcccctctcagcccatccacgtccctcagcgct
atcattagaactcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaacgt
ctgtgtcgcaggtattctcagaaactgatccagcacaccacctgtcagctgctcaggacc
tacccagccgccacgcgcatcgactcatccaaccccaaccccctcatgttctggctgcat
gggatacagctcgtggcactcaactaccagacagatgatctccctttgcatttaaacgct
gccatgtttgaggccaacggtggctgtggctatgttttgaaacccccggttctgtgggac
aagaactgtcccatgtaccagaagttttcccccttggaaagagacctggacaacatggag
cccgccgtctactctttaactgtggtctctggtcagaacgtgtgcccaagtaacagcacg
ggaagcccgtgcatcgaggtcgacgtcctgggcatgccgctggacagctgccacttccgc
acgaagcccatccatcgaaacactctgaaccccatgtggaacgagcagttcttcttccgg
gtttacttcgaagaccttgtgttccttcgttttgcagtcgtggaaaacaacagctctgca
gtcactgctcagagaatcattccgctcaaggctctaaaacgaggatatcgacatctccag
ctgcgaaacctccacaatgaagtcctagaaatctctagtttattcataaacagcagaagg
atggaagaaaattcctctggcagtactgtgccagcctctttgatgtttactacagaagaa
agaaaatgtttccaggctcacagagtcacggtgcatggggtcccaggcccagaacccttt
actgttttctccataaatggaggcaccagggcaaagcagcttctccaacaaattctaacc
tctgaacaagacaccaaacctattgccacagactattttttgatggaagaaaaatatttt
atatctaaagaaaagaatgaatgcagaaaacaaccgttccagagagccattggtccagaa
gaagagatcgtgcagatcttaaacagctggtttccagaagagggatacgttggcaggatt
gtcttgaaaacccagcaggaaaacttagaagagaaaagcattgttcaagatgacaaagag
gtgatcttgacctcggaggaggagagtttctttgtccaagtgcacgacgtttccccagag
caacctcgaaccgtcatcaaagcgccccgcgtcagcacggcgcaggatgtcattcagcag
accttatgcaaagccaagtactcctatagcattctgagcaaccccaacccgagtgactac
gtacttctggaagaggtggtgaaagacacagccaacaagaagtcttccacccccaagtcc
tcccagcgggtccttttggatcaggagtgtgtgtttcaagcccaaagcaagtggaaaggt
gcagggaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagacaaaagg
aaaggcatttcttttgcaagtgaattcaagaagctcaccaagtcgacgaaacagccccga
ggactcacatcaccttctcaggtcttgacctcagaaagtgtccaaaacaaggaggagaaa
cctgtgggcagcttgtcctccagtgatgtgacagactatcgacagtga
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