Plasmodium falciparum 3D7: PF3D7_1324800
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Entry
PF3D7_1324800 CDS
T00095
Name
(RefSeq) dihydrofolate synthase/folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pfa
Plasmodium falciparum 3D7
Pathway
pfa00790
Folate biosynthesis
pfa01100
Metabolic pathways
pfa01240
Biosynthesis of cofactors
Module
pfa_M00841
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pfa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
PF3D7_1324800
Enzymes [BR:
pfa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
PF3D7_1324800
6.3.2.17 tetrahydrofolate synthase
PF3D7_1324800
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-GeneID:
814111
NCBI-ProteinID:
XP_001349988
PlasmoDB:
PF3D7_1324800
UniProt:
Q8IE69
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Position
13:complement(join(1036543..1036586,1036713..1036835,1036981..1037179,1037329..1038531))
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AA seq
522 aa
AA seq
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MEKNQNDKSNKNDIIHMNDKSGNYDKNNINNFIDKNDEHDMSDILHKINNEEKKYEEIKS
YSECLELLYKTHALKLGLDNPKKLNESFGHPCDKYKTIHIAGTNGKGSVCYKIYTCLKIK
KFKVGLFSSPHIFSLRERIIVNDEPISEKELIHLVNEVLNKAKKLYINPSFFEIITLVAF
LHFLNKKVDYAIIETGIGGRLDATNILTKPEVIVITSIGYDHLNILGDNLPIICNEKIGI
FKKDANVVIGPSVAIYKNVFDKAKELNCTIHTVVPEPRGERYNEENSRIALRTLEILNIS
IDYFLKSIIPIKPPLRIQYLATEQIQHIKKKFSPDNLEHNVQYPLAVILDVGHNETAIDR
LCTDINYFHKGQNIRICISITKPRNLSVFHPFIAQFGDTLKDIFYLPSLNERTYDFEEIV
EMLNNEEEIKNEIKELILSSSKKVGKWLAHEKQGNINEEDALKLYKRGCIPLIIKNAFLE
CCKDNSILLVCGTFFVFDEVLNVFDIHSDMQDTIFMNEPSLV
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaaaatcaaaatgataaaagtaacaaaaatgatataattcacatgaatgataaa
agtggaaattatgataaaaataatataaataattttattgataaaaatgatgagcatgat
atgagtgacatattacataaaataaataatgaggaaaaaaaatatgaagaaataaaatct
tacagtgagtgcttagaattattatataaaacacatgccctaaaattaggacttgataac
ccaaaaaaattgaacgaatcttttggtcacccttgtgataaatataaaactattcatatt
gcagggacaaatgggaaagggtctgtatgctataaaatatatacatgtcttaaaataaaa
aaattcaaggtgggtcttttttcatcacctcatatattttctttaagagaaagaattata
gtaaacgatgaaccaataagtgaaaaagagttaatacatttagtaaacgaagtattaaat
aaagccaaaaaattatatataaatccatctttttttgaaataattacattagttgcattt
ttacattttttaaataagaaggtagattatgctataatagaaacagggattggagggcgc
ttagatgcaactaatatattaaccaaaccagaagttattgtaattacttccataggatat
gatcatttaaatatattaggtgataatttgcctattatatgtaatgaaaaaattggaatt
tttaaaaaagatgctaacgttgtaataggaccatcagtagctatttataaaaatgttttt
gataaggcaaaagaattaaattgtactatacatactgtagtacctgaaccacgaggagaa
agatataatgaagaaaattcaagaatagcattgcgcactttagaaatattaaatataagt
atagattactttttaaagtccattataccaattaaaccacctttaagaattcaatattta
gctaccgagcaaatacaacatataaagaaaaaattttcaccagataatttagaacacaat
gtacaatatcctctagctgttattttagatgtaggccacaatgaaacggcaatagataga
ttgtgtaccgatattaattattttcataagggacaaaatataaggatatgtatatctata
acaaagccgagaaacttgagtgtattccatccgttcatagctcaatttggcgacacctta
aaggatatattttaccttccatcattaaatgaaaggacctacgactttgaggaaatcgtt
gagatgttaaataatgaagaagaaataaaaaatgaaataaaagagctcatattaagtagc
tctaaaaaggttggtaaatggttagctcatgagaaacaaggaaatattaatgaagaagat
gcacttaaattatacaaaagaggatgcataccattaataatcaaaaatgcatttcttgaa
tgttgcaaagacaatagtatattattagtatgtgggacgtttttcgtgtttgatgaggtt
ttaaacgtttttgatattcactctgatatgcaagataccatttttatgaatgaaccatct
cttgtttaa
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