Pteropus giganteus (Indian flying fox): 120586714 Help Entry 120586714         CDS       T07511                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism pgig  Pteropus giganteus (Indian flying fox) Pathway pgig00230   Purine metabolism pgig01100   Metabolic pathways pgig01522   Endocrine resistance pgig04015   Rap1 signaling pathway pgig04022   cGMP-PKG signaling pathway pgig04024   cAMP signaling pathway pgig04062   Chemokine signaling pathway pgig04072   Phospholipase D signaling pathway pgig04114   Oocyte meiosis pgig04211   Longevity regulating pathway pgig04213   Longevity regulating pathway - multiple species pgig04261   Adrenergic signaling in cardiomyocytes pgig04270   Vascular smooth muscle contraction pgig04371   Apelin signaling pathway pgig04540   Gap junction pgig04611   Platelet activation pgig04713   Circadian entrainment pgig04714   Thermogenesis pgig04723   Retrograde endocannabinoid signaling pgig04724   Glutamatergic synapse pgig04725   Cholinergic synapse pgig04726   Serotonergic synapse pgig04727   GABAergic synapse pgig04728   Dopaminergic synapse pgig04750   Inflammatory mediator regulation of TRP channels pgig04911   Insulin secretion pgig04912   GnRH signaling pathway pgig04913   Ovarian steroidogenesis pgig04914   Progesterone-mediated oocyte maturation pgig04915   Estrogen signaling pathway pgig04916   Melanogenesis pgig04918   Thyroid hormone synthesis pgig04921   Oxytocin signaling pathway pgig04923   Regulation of lipolysis in adipocytes pgig04924   Renin secretion pgig04925   Aldosterone synthesis and secretion pgig04926   Relaxin signaling pathway pgig04927   Cortisol synthesis and secretion pgig04928   Parathyroid hormone synthesis, secretion and action pgig04934   Cushing syndrome pgig04935   Growth hormone synthesis, secretion and action pgig04970   Salivary secretion pgig04971   Gastric acid secretion pgig04972   Pancreatic secretion pgig04976   Bile secretion pgig05012   Parkinson disease pgig05030   Cocaine addiction pgig05031   Amphetamine addiction pgig05032   Morphine addiction pgig05034   Alcoholism pgig05163   Human cytomegalovirus infection pgig05166   Human T-cell leukemia virus 1 infection pgig05200   Pathways in cancer pgig05207   Chemical carcinogenesis - receptor activation pgig05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pgig00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     120586714 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     120586714 (ADCY5)    04371 Apelin signaling pathway     120586714 (ADCY5)    04072 Phospholipase D signaling pathway     120586714 (ADCY5)    04024 cAMP signaling pathway     120586714 (ADCY5)    04022 cGMP-PKG signaling pathway     120586714 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     120586714 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     120586714 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     120586714 (ADCY5)    04062 Chemokine signaling pathway     120586714 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     120586714 (ADCY5)    04923 Regulation of lipolysis in adipocytes     120586714 (ADCY5)    04912 GnRH signaling pathway     120586714 (ADCY5)    04913 Ovarian steroidogenesis     120586714 (ADCY5)    04915 Estrogen signaling pathway     120586714 (ADCY5)    04914 Progesterone-mediated oocyte maturation     120586714 (ADCY5)    04921 Oxytocin signaling pathway     120586714 (ADCY5)    04926 Relaxin signaling pathway     120586714 (ADCY5)    04935 Growth hormone synthesis, secretion and action     120586714 (ADCY5)    04918 Thyroid hormone synthesis     120586714 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     120586714 (ADCY5)    04916 Melanogenesis     120586714 (ADCY5)    04924 Renin secretion     120586714 (ADCY5)    04925 Aldosterone synthesis and secretion     120586714 (ADCY5)    04927 Cortisol synthesis and secretion     120586714 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     120586714 (ADCY5)    04270 Vascular smooth muscle contraction     120586714 (ADCY5)   09154 Digestive system    04970 Salivary secretion     120586714 (ADCY5)    04971 Gastric acid secretion     120586714 (ADCY5)    04972 Pancreatic secretion     120586714 (ADCY5)    04976 Bile secretion     120586714 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     120586714 (ADCY5)    04727 GABAergic synapse     120586714 (ADCY5)    04725 Cholinergic synapse     120586714 (ADCY5)    04728 Dopaminergic synapse     120586714 (ADCY5)    04726 Serotonergic synapse     120586714 (ADCY5)    04723 Retrograde endocannabinoid signaling     120586714 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     120586714 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     120586714 (ADCY5)    04213 Longevity regulating pathway - multiple species     120586714 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     120586714 (ADCY5)    04714 Thermogenesis     120586714 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120586714 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     120586714 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     120586714 (ADCY5)    05163 Human cytomegalovirus infection     120586714 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     120586714 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     120586714 (ADCY5)    05031 Amphetamine addiction     120586714 (ADCY5)    05032 Morphine addiction     120586714 (ADCY5)    05034 Alcoholism     120586714 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     120586714 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     120586714 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     120586714 (ADCY5) Enzymes [BR:pgig01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      120586714 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom PEN-2 TBK1_ULD HILPDA GBR2_CC Motif Other DBs NCBI-GeneID:  120586714 NCBI-ProteinID:  XP_039699146 LinkDB All DBs Position Unknown AA seq 1259 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADARANGYPHAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRGVDELEAGAVEG DGSSGDGGSLAGSGAGPGPVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLGVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI VPHSMFMLSFYLTCFVLLTLVIFVSVIYSCVKLFPAPLQTLSRKIVRSKVNSTLVGVFTI TLVFLAAFVNMFMCNSKDLFGCLADEHNISTSQVNACHVVESAFNYSLGDEQGFCGSPWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV TANAIDFNNNGTSQCPEHATKVALKVVTPIVISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagccgcggcgcca gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgatgcccgcgccaat ggctacccccacgcccccggcggttcggcccgcggctccaccaagagacccgggggggcg gtgaccccgcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgacgac cctccgctgagtggcgacgaccccttggccgggggctttggcttcagcttccgctctaag tcagcctggcaggagcgcggcggcgacgactgcggacgcggcagccgccggcagcggcgg ggcgcggctggcgggggcagcacccgggcgccccctgcgggcggcggtggcggctcggcg gccgcagcggccgcagccggcgggaccgaggtgcgcccccgctcggtggagctgggcctg gaggagcggcggggcaagggccgcggggtcgacgagctggaggccggcgccgtcgagggc gacgggagctccggcgatggcggcagcttggcgggctcgggcgcgggccccggcccggtg ctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctccaagaagttcccg tcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctg accatgctcatggccgtgctagtgctcgtgtgcctcgtcatgttggccttccacgcggcg cggcctccgctccagctgccctacctgggcgtgctggcggccgccgtgggcgtgatcctc gtcatggccgtgctctgcaaccgcgccgcctttcaccaagaccacatgggcctggcctgc tacgcgctcatcgcggtggtgctggccgtccaggtggtgggcctgctgctgccccagcca cgaagcgcctccgagggcatctggtggacggtgttcttcatctacaccatctacacactg ctacccgtgcgcatgcgggccgcagtactcagcggggtgctcctgtctgccctccacctg gccatcgccctgcgaaccaacgcccaggaccagttcctgctcaaacagctggtctccaat gtcctcattttctcctgcaccaacatcgtgggtgtctgcacccactatccggcagaggtc tcccagagacaggccttccaggagacccgggagtgtatccaggcacggctccactcacag cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcatgttgccatg gagatgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatttacatc cagaaacatgacaatgtgagcatcctgtttgctgacatcgagggcttcaccagcctggcg tcccagtgcacggcccaagagctggttatgaccctcaatgagctcttcgcccgcttcgac aagctggctgcggagaatcactgtttacgtattaagatcctgggggattgttattactgt gtctcggggctgcctgaagcgagggctgaccacgcccactgctgtgtggagatgggcatg gacatgattgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgc gtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcagttc gacgtctggtctaacgacgtcacgctggccaaccacatggaggctggaggcaaggctgga cgcatccacatcaccaaggccacactcaactacctgaatggagactacgaggtggagccg ggctgtgggggcgagcgcaatgcctacctcaaggagcacagcatcgagaccttcctcatc ctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaatcgccag agaaccaactccattgggcacaacccgccgcactggggggctgagcgccccttctacaac cacttgggcggcaaccaggtgtccaaggagatgaagcggatgggcttcgaagaccccaag gacaagaatgcccaggaaagcgcgaaccccgaggatgaagtggatgaattcctgggccga gccatcgacgccaggagtattgacaggctgcggtctgagcatgttcgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattcggt gcctatgtggcgtgtgcctcgcttgtcttcctcttcatttgctttgtccagatcaccatc gtgccccactccatgttcatgttgagtttctacctgacctgtttcgtgctgctgaccttg gtgatatttgtgtccgtcatctactcctgtgtgaagctcttccccgcccctctgcagacc ctctccaggaagatcgtgcggtccaaggtgaacagcaccctggttggggtgttcaccatc accctggtgttcctggcagcatttgtcaacatgttcatgtgcaactccaaggacctattc ggctgcctggcggatgagcacaacatcagcaccagccaggtcaacgcttgccacgtggtg gagtcggccttcaactacagcctgggtgacgagcagggattctgtggcagcccctggccc aactgcaacttccctgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcata tatgtgctcgtcgtcgaagtgcccggtgtcacactctttgacaatgcagacctgctagtc accgccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcacgcgacc aaagtggcgctgaaggtggtgacgcccattgtcatctcagtctttgtgctggccctgtac ctgcacgcccagcaggtggagtccaccgcccgcctcgacttcctctggaaactgcaggcc acggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaac atcctgcccaaggacgtggccgcccacttcctggcccgtgagcggcgcaacgacgagctc tactatcagtcgtgtgagtgcgtggccgtcatgttcgcctccatcgctaacttctccgag ttctatgtggagctggaggccaacaacgagggtgtcgagtgcttgcggctgcttaatgaa atcatcgccgatttcgacgagatcatcagcgaggatcggttcaggcagctggaaaagatc aagaccattggcagcacctacatggctgcctcaggcctcaatgattccacctatgacaag gtgggcaagacccacatcaaggctctggccgacttcgccatgaagctgatggaccagatg aagtacatcaacgagcactccttcaacaacttccagatgaagattgggctcaatattggc cccgtggtggccggggtgatcggggcccgcaagcctcagtacgacatctggggcaatacg gtgaatgtggccagccgcatggacagcacaggtgtgcctgaccgcatccaggtcaccacg gacatgtatcaggtgctggctgccaacacataccagctggagtgccggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaacggagggcccccgctcagttag

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