KEGG   Pteropus giganteus (Indian flying fox): 120597692
Entry
120597692         CDS       T07511                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pgig  Pteropus giganteus (Indian flying fox)
Pathway
pgig01522  Endocrine resistance
pgig04010  MAPK signaling pathway
pgig04015  Rap1 signaling pathway
pgig04068  FoxO signaling pathway
pgig04071  Sphingolipid signaling pathway
pgig04114  Oocyte meiosis
pgig04148  Efferocytosis
pgig04218  Cellular senescence
pgig04261  Adrenergic signaling in cardiomyocytes
pgig04370  VEGF signaling pathway
pgig04380  Osteoclast differentiation
pgig04550  Signaling pathways regulating pluripotency of stem cells
pgig04611  Platelet activation
pgig04613  Neutrophil extracellular trap formation
pgig04620  Toll-like receptor signaling pathway
pgig04621  NOD-like receptor signaling pathway
pgig04622  RIG-I-like receptor signaling pathway
pgig04625  C-type lectin receptor signaling pathway
pgig04657  IL-17 signaling pathway
pgig04658  Th1 and Th2 cell differentiation
pgig04659  Th17 cell differentiation
pgig04660  T cell receptor signaling pathway
pgig04664  Fc epsilon RI signaling pathway
pgig04668  TNF signaling pathway
pgig04670  Leukocyte transendothelial migration
pgig04714  Thermogenesis
pgig04722  Neurotrophin signaling pathway
pgig04723  Retrograde endocannabinoid signaling
pgig04728  Dopaminergic synapse
pgig04750  Inflammatory mediator regulation of TRP channels
pgig04912  GnRH signaling pathway
pgig04914  Progesterone-mediated oocyte maturation
pgig04917  Prolactin signaling pathway
pgig04926  Relaxin signaling pathway
pgig04932  Non-alcoholic fatty liver disease
pgig04933  AGE-RAGE signaling pathway in diabetic complications
pgig04935  Growth hormone synthesis, secretion and action
pgig04936  Alcoholic liver disease
pgig05014  Amyotrophic lateral sclerosis
pgig05020  Prion disease
pgig05022  Pathways of neurodegeneration - multiple diseases
pgig05132  Salmonella infection
pgig05133  Pertussis
pgig05135  Yersinia infection
pgig05140  Leishmaniasis
pgig05142  Chagas disease
pgig05145  Toxoplasmosis
pgig05152  Tuberculosis
pgig05161  Hepatitis B
pgig05163  Human cytomegalovirus infection
pgig05167  Kaposi sarcoma-associated herpesvirus infection
pgig05169  Epstein-Barr virus infection
pgig05170  Human immunodeficiency virus 1 infection
pgig05171  Coronavirus disease - COVID-19
pgig05205  Proteoglycans in cancer
pgig05208  Chemical carcinogenesis - reactive oxygen species
pgig05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pgig05415  Diabetic cardiomyopathy
pgig05417  Lipid and atherosclerosis
pgig05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120597692 (MAPK14)
   04015 Rap1 signaling pathway
    120597692 (MAPK14)
   04370 VEGF signaling pathway
    120597692 (MAPK14)
   04668 TNF signaling pathway
    120597692 (MAPK14)
   04068 FoxO signaling pathway
    120597692 (MAPK14)
   04071 Sphingolipid signaling pathway
    120597692 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    120597692 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    120597692 (MAPK14)
   04218 Cellular senescence
    120597692 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    120597692 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    120597692 (MAPK14)
   04613 Neutrophil extracellular trap formation
    120597692 (MAPK14)
   04620 Toll-like receptor signaling pathway
    120597692 (MAPK14)
   04621 NOD-like receptor signaling pathway
    120597692 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    120597692 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    120597692 (MAPK14)
   04660 T cell receptor signaling pathway
    120597692 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    120597692 (MAPK14)
   04659 Th17 cell differentiation
    120597692 (MAPK14)
   04657 IL-17 signaling pathway
    120597692 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    120597692 (MAPK14)
   04670 Leukocyte transendothelial migration
    120597692 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120597692 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    120597692 (MAPK14)
   04917 Prolactin signaling pathway
    120597692 (MAPK14)
   04926 Relaxin signaling pathway
    120597692 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    120597692 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120597692 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    120597692 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    120597692 (MAPK14)
   04722 Neurotrophin signaling pathway
    120597692 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120597692 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    120597692 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    120597692 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    120597692 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    120597692 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120597692 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    120597692 (MAPK14)
   05161 Hepatitis B
    120597692 (MAPK14)
   05171 Coronavirus disease - COVID-19
    120597692 (MAPK14)
   05163 Human cytomegalovirus infection
    120597692 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120597692 (MAPK14)
   05169 Epstein-Barr virus infection
    120597692 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120597692 (MAPK14)
   05135 Yersinia infection
    120597692 (MAPK14)
   05133 Pertussis
    120597692 (MAPK14)
   05152 Tuberculosis
    120597692 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    120597692 (MAPK14)
   05140 Leishmaniasis
    120597692 (MAPK14)
   05142 Chagas disease
    120597692 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    120597692 (MAPK14)
   05020 Prion disease
    120597692 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    120597692 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120597692 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    120597692 (MAPK14)
   05415 Diabetic cardiomyopathy
    120597692 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120597692 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    120597692 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    120597692 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    120597692 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pgig01001]
    120597692 (MAPK14)
Enzymes [BR:pgig01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     120597692 (MAPK14)
Protein kinases [BR:pgig01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   120597692 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 120597692
NCBI-ProteinID: XP_039712266
LinkDB
Position
Unknown
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggaaaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
ccagagcgttaccagaacctgtctccggtgggctccggcgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctatccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctagtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctcaagtat
atacattcagccgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcctggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactatattcag
tctttgacccagatgccgaagatgaactttgcaaatgtatttattggtgccaatcccttg
gctgttgacttgctggagaagatgcttgtattggactcagataagagaatcactgcagcc
caggccctcgcacatgcctactttgctcaatatcatgatcctgatgacgaaccagtggct
gatccttacgatcaatcctttgaaagcagggacctccttatagatgaatggaaaagcctg
acctatgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggaatcc
tga

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